Term
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Definition
| Cells contain granules containing mediators of inflammation; surface coated with receptors that can trigger exocytosis of granules; Degranulate upon direct chemical injury |
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Term
| Mast Cell role in pathology |
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Definition
| involved in allergy, anaphylaxis and acute inflammation; causes vasodilation and chemotaxis |
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Term
| What are some of the effects of mast cells? |
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Definition
| Edema (fluid in interstitial space), Warmth of core body temp, redness, and attraction of inflammatory cells to the site. |
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Term
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Definition
| Disc-like cytoplasmic fragments of megakaryocytes; no nuclei, just ER and mitochondria |
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Term
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Definition
| Activated by endothelial injury/exposure to collagen; coagulation; plugs gaps in vessel walls; release growth factors and chemotaxins |
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Term
| Endothelial cell morphology |
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Definition
| "fried eggs"; thin cytoplasm and round nucleus |
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Term
| Function of endothelial cells |
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Definition
| line vessels and keep cells and plasma inside; disruption initiates inflammation; |
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Term
| What do damaaged endothelial cells secrete? |
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Definition
| prostaglandins (vasodilation) and adhesion molecules (extravasation) |
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Term
| Natural Killer Cell morphology |
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Definition
| round cells that look like lymphocytes with more cytoplasm |
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Term
| Function of Natural Killer Cells |
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Definition
| recognize common antigens on surface of bacteria and foreign cells; kill infected and tumor cells; |
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Term
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Definition
| Neutrophils, Basophils and Eosinophils |
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Term
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Definition
| Large (bigger than RBCs), round, multi-lobed, granulated |
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Term
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Definition
| Acute Inflammation, phagocytosis, chemotaxis |
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Term
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Definition
| inflamation in response to alleries and parasitic infections |
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Term
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Definition
| least common; inflammation in response to allergic reactions |
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Term
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Definition
| Long spinde-shaped cell in extracellular matrix |
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Term
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Definition
| produce ground substance and fibers to heal wounds |
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Term
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Definition
| small ells with basophilic cytoplasm; make up 25% of WBCs |
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Term
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Definition
| anitgen presenting and antibody secreting |
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Term
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Definition
| secretes cytokines, recruit leukocytes from the blood, and kill labeled infected cells |
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Term
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Definition
| Activate B and T cells; communiates with lymphokines; |
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