Shared Flashcard Set

Details

Cell Membranes and Movement of Molecules
N/A
14
Physiology
Undergraduate 2
05/05/2012

Additional Physiology Flashcards

 


 

Cards

Term
plasma membrane
Definition
"limiting membrane" that surrounds the cell

encloses intracellular fluid
Term
organelles
Definition
"little organs" within the confines of the cell

each organelle performs a specific function contributing to cell survival
Term
intracellular fluid
Definition
consists of all the fluid located within the confines of the cell membrane.

Can be further classified into cytoplasm and cytosol
Term
cytoplasm
Definition
includes the intracellular fluid that is located outside of the nucleus
Term
cytosol
Definition
intracellular fluid which includes that portion of the cytoplasm outside of the organelles
Term
membrane function
Definition
selective barrier restricting movement of molecules into and out of the cell

location of receptors which are able to detect signals from other cells

link cells to adjacent cells

anchor cells to the extracellular matrix
Term
membrane structure
Definition
comprised primarily by phospholipids

phospholipids are amphipathic (polar and nonpolar ends)

because of their amphipathic make-up, when grouped together, phospholipids naturally align into a bimolecular layer

the fact that there are no molecular bonds between these molecules results in a membrane with fluidity

cholesterol is also present in the membrane and adds to its fluidity (temperature dependent)
Term
membrane proteins
Definition
integral membrane proteins and peripheral membrane proteins

carbohydrates often bind to proteins extending off the surface of the cell. This forms a structure called a glycoprotein, which is important to cell identification and interaction.

fluid mosaic model of the cell membrane--membrane proteins float in a sea of lipids
Term
integral membrane proteins
Definition
amphipathic and integrate themselves into the membrane

many are transmembrane proteins that span the entire width of the membrane

suited to function as channels through which materials can be transported (water, ions, chemical signals, etc.)
Term
peripheral membrane proteins
Definition
polar molecules and therefore do not integrate into the membrane

polar aspect of these proteins binds to the polar portion of the membrane

most of these are on the cytosolic surface (inside) of the membrane
Term
membrane junctions
Definition
desmosomes

tight junctions

gap junctions
Term
desmosomes
Definition
localized connections between adjacent but non-touching cells

anchor cells together

common in tissue that is subject to stretching (i.e. skin, cardiac muscle)

protein fibers connect between cells, holding them firmly together keep the cells from being pulled apart

not occlusive junctions

"spot weld" or "rivet" or "anchoring junction"
Term
tight junctions
Definition
present where two plasma membranes are joined together, thereby sealing off the passageway between adjacent cells.

extends around circumference of a cell (unlike desmosomes)

restrict the uncontrolled movement of substances between cells (paracellular movement) by limiting the movement of hydrophilic substances between cells (lipophilic substances can still diffuse directly through the cell membrane and will not be limited by tight junctions)

most common in cells that line absorptive surfaces, such as are seen in the gastrointestinal tract and kidney.
Term
gap junctions
Definition
"communicating junctions"

comprised of small channels made up of subunits called connexons which connect the cytosol of adjacent cells.

allow passage of small, water-soluble particles to pass between connected cells

important in the conduction of electrical impulses between adjacent cells, as seen in smooth and cardiac muscle

allow movement of other molecules involved with activities other than electrical signaling
Supporting users have an ad free experience!