Term
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Definition
Abnormal accumulation of lipids/triglycerides in cells.. most often in liver.
Due to starvation or diabetics |
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Term
| Inherited Lysosomal Storage Diseases |
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Definition
Gaucher's Disease: accumulation of cerebrosides.
Tay Sach's Disease: accumulation of gangliosides.
Hunger's Syndrome: accumulation of mucopolysacharides |
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Term
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Definition
| yellow to brown granular iron storage protein. |
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Term
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Definition
| "wear and tear" protein.. looks like golden brown graunules in terminally differentiated cells (neurons, cardiac myocytes) or cells that infrequently cycle (hepatocytes)... INCREASES WITH AGE |
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Term
| ENDOGENOUS pigments vs EXOGENOUS pigments |
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Definition
Cells accumulate pigments that cannot be digested, endogenous pigments: melanin, hemosiderin, lipofuscin
exogenous pigments: Carbon (anthracosis) |
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Term
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Definition
| abnormal deposition of calcium salts.. commonly has two forms: dystrophic calcification and metastatic calicification |
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Term
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Definition
| occurs in nonviable or dying tissues: in AREAS of NECROSIS but has normal calcium-phosphorous metabolism |
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Term
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Definition
| abnormal accumulation of calcium in normal, live tissue, except that the tissue has HYPERCALCEMIA |
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Term
| Difference between Metastatic and Dystrophic Calcification |
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Definition
| Dystrophic is in dead (usually necrotic) tissue whereas Metastatic is in living tissue that has Hypercalcemia.. abnormal caclicum phosphorous metabolism |
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