Term
| Class of enzymes known as ---- removes phosphate groups thus reversing the action of Kinases. |
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Definition
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Term
| Enzymes which add phosphate groups from ATP to proteins are known as protein ----. |
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Definition
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Term
| Membrane receptors are usually: |
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Definition
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Term
| Small molecules or ions that relay signals inside the cell, are called: --- --- |
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Definition
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Term
| Name the three subclasses of membrane receptors: |
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Definition
| Enzymatic receptors, G protein-coupled receptors, channel-linked receptors. |
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Term
| Intracellular receptors bind hydro---- Ligands, which easily cross the ----. |
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Definition
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Term
| membrane receptors bind hydro---- ligands, and cannot cross the ---- easily |
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Definition
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Term
| Order the steps of signaling via a GPCR as they occur in the cell. |
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Definition
| Receptor binds signal, Activation of G protein, Activation of effector protein, cellular response. |
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Term
| Membrane receptors are usually ---- proteins. |
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Definition
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Term
| Function of G protein - coupled receptors: |
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Definition
| Binding of a singnal to receptor causes GTP to bind a G protein; G protein, wiht attached GTP, detaches to deliver the signal inside the cell. |
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Term
| Example of a G protein -coupled receptor |
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Definition
| Peptide hormones, rod cells in the eye. |
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Term
| Example of enzymatic recepotors: |
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Definition
| Phosphorylation of protein kinases |
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Term
| Example of chemically gated ion channels: |
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Definition
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Term
| What are the 5 groups in the GPCR family? |
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Definition
| Glutamate, Frizzled/taste 2, adhesion, Rhodonsin, Secretin |
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Term
| In cell signaling, the conversion of the information conveyed by the signaling molecule into a cellular response is know as: |
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Definition
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Term
| Two compounds that act as second messengers: |
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Definition
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Term
| 2 basic mechanisms that can inactivate RTK's: |
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Definition
| Internalizaion and dephosphorylation |
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Term
| Signaling molecules exert their effects on cells through signal ---- pathways |
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Definition
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Term
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Definition
| They are agents that, when present, activate MAP-kinases and cause a cell to divide. |
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Term
| Receptor tyrosine Kinases (RTK) regoginze ---- ligands |
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Definition
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