Term
|
Definition
| the chromosomes appear as long, thin, threads within the nuclues |
|
|
Term
|
Definition
| period when gene expression is active and chromosomal duplication occurs |
|
|
Term
|
Definition
| the chromosomes adopt a higly compacted/condensed appearance |
|
|
Term
|
Definition
| period when gene expression is significantly reduced |
|
|
Term
|
Definition
| is localized at the nuclear periphery and contains DNA sequence information that is transcriptionally repressed |
|
|
Term
|
Definition
| appears as a speckled mass of material throughout the nucleus and contains DNA sequences that are transcriptionally active |
|
|
Term
|
Definition
| chromosomes that contain genes that code for ribosomal RNA that localize to this region of the nucleus |
|
|
Term
|
Definition
|
|
Term
|
Definition
| DNA compacted 10,000-fold |
|
|
Term
|
Definition
| the complex of both classes of protein (histone and nonhistone) with nuclear DNA |
|
|
Term
|
Definition
| 147 paired nucleotides wound around a protein core with a ~80 paired nucleotide region |
|
|
Term
|
Definition
| the ~146 paired nucleotide proteins wound around the protein core (nucelosome minus the linker) |
|
|
Term
| 1st Level of Chromatin Packaging |
|
Definition
| "beads-on-a-string"; nucleosomes |
|
|
Term
| 2nd Level of Chromatin Packaging |
|
Definition
| Histone H1 mediated event; bind to linker 30nm fiber; Zig-zag model of assembly |
|
|
Term
| 3rd Level of Chromatin Packaging |
|
Definition
| Mechanism is unclear; formation of loops from a central axis |
|
|
Term
| 4th Level of Chromatin Packaging |
|
Definition
| Further packaging of loops |
|
|
