Term
| Drugs that depolymerize microfilaments |
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Definition
| latrunculin, cytochalasin |
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Term
| Drugs that depolymerize microtubules |
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Definition
| nocodazole, culchicine, colcemid |
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Term
| Drugs that stabilize microtubules |
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Definition
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Term
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Definition
| proteoglycan, collagen, fibronectin/laminin, microfilaments, integrins |
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Term
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Definition
| microtubules, microfilaments, intermediate filaments |
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Term
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Definition
| microtubule-based; sliding movement; facilitates cilia and flagella movement |
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Term
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Definition
| barrier function; holds cells together |
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Term
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Definition
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Term
| Basic signal transduction pathway |
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Definition
ligand binds to receptor
alters shape
activates kinase that uses ATP to phosphorylate tyrosine
leads to alteration in transcription |
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Term
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Definition
| microtubule-based; walk along microtubules transporting chromosomes and other cell components |
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Term
| Secondary Messengers (and basic pathway) |
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Definition
PIP2 --> IP3
IP3 opens calcium ion channel in endoplasmic reticulum
calcium ions activate proteins causing cell response |
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Term
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Definition
| actin-based motor protein; muscle contraction and force for cell division; walk along actin filaments |
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Term
| Drugs that stabilize microfilaments |
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Definition
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Term
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Definition
ECM components
receptor proteins |
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Term
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Definition
ECM components
provide structure |
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Term
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Definition
ECM component
made of protein and glycosamioglycans
space-filling |
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Term
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Definition
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Term
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Definition
ECM components
responsible for adhesion |
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Term
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Definition
| junction that provides mechanical strength between epithelial cells |
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Term
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Definition
| small molecule conduits between cells |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| bands around epithelial cells necessary for adhesion; contain cadherins |
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Term
| Cadherin depends on... (ion) |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| phosphorylated Erk, which activates TF |
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Term
| TGF-beta nuclear proteins |
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Definition
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Term
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Definition
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Term
| Hedgehog nuclear proteins |
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Definition
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Term
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Definition
| alters adaptor attached to GEF, activating RAS G-protein to RAS GFP (active form); this converts Rat to Mek, causing phosphorylation of Erk activating TF |
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Term
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Definition
| SMAD is phosphorylated then forms complex with coSMAD; enters nucleus to alter transcription |
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Term
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Definition
| Dsh inhibits destruction complex, activating catenin which activates TCF/LEF to alter gene expression |
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Term
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Definition
| Hedgehog inhibits inhibitory effects of patched and smoothened, leading to phosphorylation of Ci, which then acts on target genes |
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Term
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Definition
| depolymerizes microtubules |
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Term
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Definition
| depolymerizes microtubules |
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Term
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Definition
| depolymerizes microtubules |
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Term
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Definition
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Term
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Definition
| depolymerizes microfilaments |
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Term
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Definition
| depolymerizes microfilaments |
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Term
|
Definition
| stabilizes microfilaments |
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