Term
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Definition
| occurs between two cell adhesions of the same type |
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Term
| Heterophilic CAM junctions |
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Definition
| occurs between two cell junctions of different types |
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Term
| Explain the origin of the name of cadherin junction |
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Definition
| Calcium dependent adhesion |
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Term
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Definition
| to the terminal sugar groups of oligosaccharide chains (glycoproteins, proteoglycans) |
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Term
| Why do they call come lectins agglutins? |
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Definition
| Lectins have multiple binding sites |
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Term
| What determines someone's blood group? |
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Definition
| carbohydrate on glycolipids and glycoproteins on the red blood cell |
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Term
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Definition
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Term
| Plasma universal recipient |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| three main FUNCTIONAL categories of cell junctions |
|
Definition
1) tight (zonula occludens) (occluding) junctions
2) adhering (zonula adheren, macula adheren) (adhesive) junctions
3) gap (communicating) junctions |
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|
Term
| Where are zonula occludens? |
|
Definition
just below the apical membrane
form the definition of apical vs. basolateral |
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Term
| two functions of zonula occludens |
|
Definition
1) keep most molecules from entering into the inter membrane space
2) define the apical membrane from the basolateral membrane |
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Term
| Name two types of adhering junctions |
|
Definition
1) zonula adherens
2) macula adherens |
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Term
| Where are the zonula adherens? |
|
Definition
| just under the tight junctions |
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Term
|
Definition
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Term
|
Definition
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Term
| What cytoskeletal element binds to the zonula adherens? |
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Definition
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|
Term
| Synonym for macula adherens |
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Definition
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Term
| Where are macula adherens |
|
Definition
| scattered all over the lateral surfaces of the cell |
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|
Term
| what cytoskeletal element interacts with the macula adherens? |
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Definition
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|
Term
| what size molecule gets through a gap junction? |
|
Definition
| up to about 1,200 Daltons |
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Term
| Name adhesive proteins found in the ECM (4) |
|
Definition
1) fibronectin
2) laminin
3) collagen
4) elastin |
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|
Term
| name two unusual amino acids in collagen |
|
Definition
1) hydroxylysine
2) hydroxylproline |
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Term
|
Definition
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Term
|
Definition
| degrade the ECM, cancer cells use them to invade other cells, inflammatory cells use them to respond to injury |
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Term
| what type of receptor binds to ECM fibers? |
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Definition
|
|
Term
| what type of cell junctions do plants have that animals don't? |
|
Definition
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|
Term
| How do plasmodesmatas differ from gap junctions? |
|
Definition
| they are much bigger. they are about 200 nm in diameter. this allows whole organelles and big molecules to go across the membrane |
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Term
| how can loss of cadherin promote cancer growth? |
|
Definition
| it can allow the cancer cells to travel to other places and transition from benign to invasive |
|
|
Term
| how can gain of cadherin promote cancer growth? |
|
Definition
| it can promote invasion and metastasis |
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|
Term
| Why does a plant need a cell membrane |
|
Definition
| to act as a selective permeability barrier |
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Term
| what is ground substance? |
|
Definition
| fibers embedded in a viscous gel made up of glycoproteins, glycosaminoglycans, and proteoglycans, form a gooey substance, give the cell time to recognize and treat harmful substances |
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|
Term
| what is the basement membrane or basal lamina? |
|
Definition
| provides anchoring matrix for cells |
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Term
|
Definition
| mostly protein with 1 or more short oligosaccharide chains made up of 6-8 sugar types |
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Term
|
Definition
| protein with one or more GAG covalently attached to it |
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Term
|
Definition
glycosaminoglycan
repeating dimers of an amino sugar and a sugar or sugar acid
sulfating makes the GAG highly negatively charged - attracts water and cations |
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Term
|
Definition
| only GAG that isn't usually attached to a protein |
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Term
| Cell-cell adhesion molecules (4) |
|
Definition
1) CAMs (cell adhesion molecules)
2) cadherins
3) selectins
4) integrins |
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Term
|
Definition
|
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Term
|
Definition
| cell surface glycoprotein the binds to terminal sugars on other cells |
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|
Term
| What are zonula occludes regulated by? |
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Definition
|
|
Term
| Desmosomes - special hair |
|
Definition
| intermediate filaments make hairpin turn in the attachment plaque on the cytoplasmic face |
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|
Term
| what is the cutoff of MW that gap junctions allow ionic communication between cells? |
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Definition
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|
Term
| t/f not all collagen is alike |
|
Definition
| true can be about 25 different types of collagen |
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Term
| Proteoglycan function (5) |
|
Definition
1) control diffusion
2) barrier to bacteria
3) lubrication
4) modulate growth factor activity
5) packaging histamine in mast cells |
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Term
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Definition
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Term
|
Definition
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Term
|
Definition
| membrane receptor that binds to ECM |
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