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Cell and Molecular Biology
Chapter 12 vocab
24
Biology
Undergraduate 1
10/09/2011

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Term
Action Potential
Definition
rapid, transient, self-propagating electrical signal in the plasma membrane of a cell such as a neuron or muscle. a nerve impulse
Term
active transport
Definition
movement of a molecule across a membrane driven by ATP hydrolysis or another form of metabolic energy
Term
axon
Definition
long thin nerve cell process capable of rapidly conducting nerve impulses over long distances so as to deliver signals to other cells
Term
channel
Definition
an aqueous pore in a lipid membrane, with walls made of protein, through which selected ions or molecules can pass
Term
coupled transporter
Definition
membrane transport protein that carries out transport in which the transfer of one molecule depends on the simultaneous or sequential transfer of a second molecule
Term
electrochemical gradient
Definition
driving force that causes an ion to move across a membrane. caused by differences in ion concentration and in electrical charge on either side of the membrane
Term
ion channel
Definition
transmembrane protein or protein complex that forms a water filled channel across the lipid bilayer through which specific inorganic ions can diffuse down their electrochemical gradient.
Term
ligand-gated channel
Definition
an ion channel that opens when it binds a small molecule such as a neurotransmitter
Term
membrane potential
Definition
voltage difference across a membrane due to a slight excess of positive ions on one side and of negative ions on the other. a typical membrane potential for an animal cell plasma membrane is -60mV (inside negative), measured relative to the surrounding fluid.
Term
membrane transport protein
Definition
any protein embedded in a membrane that serves as a carrier of ions or small molecules from one side to the other
Term
Na+-K+ pump
Definition
Transmembrane carrier protein, found in the plasma membrane of most animal cells, that pumps Na+ out of and K+ into the cell, using the energy derived from ATP hydrolysis
Term
Nernst equation
Definition
quantitative expression that relates the equilibrium ratio of concentrations of an ion on either side of a permeable membrane to the voltage difference across the membrane
Term
nerve terminal
Definition
the ending of an axon from which signals are sent to adjoining cells, usually at a synapse
Term
neuron
Definition
cell with long processes specialized to receive, conduct, and transmit signals in the nervous system
Term
neurotransmitter
Definition
small signaling molecule secreted by a nerve cell at a chemical synapse to signal to the postsynaptic cell. examples include acetylcholine , glutamate, GABA, and glycine.
Term
osmosis
Definition
net movement of water molecules across a semipermeable membrane driven by a difference in concentration of solute on either side. the membrane must be permeable to water but not to the solute molecules
Term
osmotic pressure
Definition
pressure that must be exerted on the low solute concentration side of a semipermeable membrane to prevent the flow of water across the membrane as a result of osmosis
Term
passive transport
Definition
the movement of a small molecule or ion across a membrane due to a difference in concentration or electrical charge
Term
patch-clamp recording
Definition
technique in which the tip of a small glass electrode is sealed onto a patch of cell membrane, thereby making it possible to record the flow of current through individual ion channels in the patch
Term
stress-gated channel
Definition
membrane protein that allows the selective entry of specific ions into a cell and is opened by mechanical force
Term
synapse
Definition
specialized junction between a nerve cell and another cell (nerve cell, muscle cell, gland cell) across which the nerve impulse is transferred. in most synapses the signal is carried by a neurotransmitter, which is secreted by the nerve cell and diffuses to the target cell.
Term
synaptic vesicle
Definition
small membrane-enclosed sac filled with neurotransmitter that releases its contents by exocytosis at a synapse.
Term
transporter
Definition
membrane protein that transports ions or molecules across a cell membrane
Term
voltage-gated channel
Definition
membrane protein that selectively allows ions such as Na+ (carried by the voltage-gated Na+ channel) to cross a membrane and is opened by changes in membrane potential. found mainly in electrically excitable cells such as nerve and muscle.
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