Term
Lab
SF: crystals, high WBC, >80%PMN |
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Definition
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Term
Lab:
SF: high WBC, >90%PMN, culture |
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Definition
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Term
|
Definition
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Term
| Lab: SF: High WBC, >70% PMN |
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Definition
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Term
Lab:
SF: Moderate WBC, >50% PMN |
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Definition
| Reiter syndrome (reactive arthritis) |
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Term
Lab:
SF: Low to moderate WBC, ANA + |
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Definition
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|
Term
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Definition
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Term
| axial skeleton, pelvis, sacroiliac joints |
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Definition
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Term
| oligoarticular asymmetrical |
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Definition
| reiter syndrome (reactive arthritis) |
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Term
| symmetrical, small joints |
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Definition
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Term
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Definition
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Term
| monoarticular or oligoarticular |
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Definition
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Term
| podagra, rapid onset of attack, tophi |
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Definition
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|
Term
|
Definition
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|
Term
| rheumatoid nodules, extra-articular |
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Definition
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|
Term
| urethritis, conjunctivitis, skin and mucous membranes |
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Definition
| reiter syndrome (reactive arthritis) |
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Term
| uveitis, aortic insufficiency, enthesopathy |
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Definition
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Term
| nonerosive joint disease, autoantibodies, multiorgan disease |
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Definition
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Term
|
Definition
| septic or crystal induced |
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|
Term
| pauciarthrits or oligoarthritis (2-4) |
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Definition
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|
Term
| polyarthritis (5 or more joints) |
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Definition
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Term
|
Definition
| erosive psoriatic arthritis |
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Term
|
Definition
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Term
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Definition
calcification of outer rim of annulus fibrosis, bamboo spine;
ankylosing spondylitis |
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Term
| impaired renal function, dehydration, acidosis, low-dose aspirin, diuretics, levodopa, lead, ethanol, cyclosporine, hypothyroidism, pyrazinamide |
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Definition
| all cause decreased urate excretion |
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Term
| ethanol, myeloproliferative disease, ineffective erythropoiesis (sickle cell, thalassemia), widespred psoriasis, cytotoxic drugs, glycogen storage disease, G6PD def, HGPRTase def, increased PRPP synthetase activity |
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Definition
| increased urate production |
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Term
| most significant stimulus to uric acid overproduction |
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Definition
| alcohol--> can increase de novo synthesis thru effects on ATP metabolism |
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|
Term
| 2/3 of pts with gout are due to.... |
|
Definition
| impairment of renal clearnace of uric acid |
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Term
|
Definition
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|
Term
| drug of choice in a patient with gout and concurrent nephropathy |
|
Definition
| allopurinol (better for kidneys, but still toxic) or febuxostate (nonpurine inhibitor of xanthine oxidase) |
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