Term
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Definition
| Relationship between drug concentration at the site of action and the resulting effect, including the time course and intensity of therapeutic and adverse effects |
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Term
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Definition
| Study of absorption, distribution, and elimination of drugs |
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Term
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Definition
histamine mediated reaction that can occur with vancomycin
and is dependent on the rate of infusion |
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Term
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Definition
| persistent suppression of bacterial growth after antimicrobial exposure |
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Term
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Definition
| Institutional profile of antimicrobial susceptibility results of a microbial species to a battery of antimicrobial agents |
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Term
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Definition
| The activity of an antimicrobial combination is greater than that expected from the additive activity of the individual agents |
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Term
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Definition
| Antibiotic-impregnated strips containing a continuous gradient drug; used to measure MIC |
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Term
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Definition
| in a population of bacteria in which the MIC of each isolate has been determined, the antibiotic concentration that inhibits 50% of the bacteria. |
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Term
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Definition
| in a population of bacteria in which the MIC of each isolate has been determined, the antibiotic concentration that inhibits 90% of the bacteria. |
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Term
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Definition
| Time above the MIC (pharmacodynamic parameter) |
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Term
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Definition
| Area under the curve to MIC ratio (pharmacodynamic parameter) |
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Term
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Definition
| Peak to MIC ratio (pharmacodynamic parameter) |
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