Term
IL-1(Beta), IL-1(beta) receptor, TNF-(alpha), & IL-10
are associated with _[outcome]_ caused by _[organism]_ |
|
Definition
Gastric carcinoma
H. pylori |
|
|
Term
| H. pylori infection decreases the likelihood of emergence of which 2 diseases? |
|
Definition
|
|
Term
| H. pylori decreases appetite by altering blood levels of ___ & ___. |
|
Definition
|
|
Term
| How does eradication of H pylori infection affect appetite? |
|
Definition
Getting better increases appetite
(weight gain) |
|
|
Term
|
Definition
|
|
Term
| Growing conditions of H pylori |
|
Definition
Microaerophilic
Acid tolerant
Non-invasive |
|
|
Term
| WW infection rate of H. pylori? |
|
Definition
|
|
Term
| What percentage of H. pylori infectees will develop gastric cancer or PED? |
|
Definition
|
|
Term
| Most common source of H. pylori infection? |
|
Definition
|
|
Term
| Principle reservoir of H. pylori? |
|
Definition
|
|
Term
| How does age affect H pylori infection rates? |
|
Definition
|
|
Term
| Risk factors for H. pylori? |
|
Definition
-Crowding
-Gastroenterology
-Familial contact |
|
|
Term
| Significance of CagA-positive strains of H pylori? |
|
Definition
Signify increased likelihood of gastric ulcers and gastric carcinoma.
(a marker) |
|
|
Term
| Significance of VacA-positive strains of H pylori? |
|
Definition
| Presence of VacA cytotoxin results in the formations of ulcers and risk of cancer |
|
|
Term
| Significance of Urease in H pylori infections? |
|
Definition
| Urease is essential for H.pylori to survive in the stomach. *Increase pH? or decrease? |
|
|
Term
| Significance of LPS in H pylori infection? |
|
Definition
Deregulates control of
1) Acid
2) Pepsinogen
It also causes autoantibodies
-Autoantibodies lead to inflammation, then cell destruction, then dysregulation of p53, then gastric atrophy, then gastric carcinoma. |
|
|
