| Term 
 
        | What is a seizure and what causes one? |  | Definition 
 
        | Seizure is a disturbance of electrical activity in the brain that may affect consciousness, motor activity, and sensation? Caused by abnormal or uncontrollable neuronal discharges in the brain
 |  | 
        |  | 
        
        | Term 
 
        | What are the different kinds of seizures? |  | Definition 
 
        | Partial seizures Generalized seizures
 Clonic-tonic (grand mal
 Ataxic (drop seizures)
 |  | 
        |  | 
        
        | Term 
 
        | Describe the the different kinds of seizures? 
 Partial seizures
 Generalized seizures
 Clonic-tonic (grand mal
 Ataxic (drop seizures)
 |  | Definition 
 
        | Partial seizures- no loss of consciousness, altered motor activity to one site of the body, may have sensory symptoms Generalized seizures- Absence seizure; nonconvulsive with loss of consciousness, slight loss of muscle tone
 Clonic-tonic (grand mal)- stiffening and relaxing of the body. Loss of consciousness
 Ataxic (drop seizures)- loss of muscle tone of consciousness
 |  | 
        |  | 
        
        | Term 
 
        | What s/s would you expect from a client after a seizure? |  | Definition 
 
        | urinary incontinence, disorientation, c/o feeling tired, headache sore muscles |  | 
        |  | 
        
        | Term 
 
        | What are the actions of anticonvulsants? |  | Definition 
 
        | suppress neuronal activity just enough to prevent abnormal or repetitive firing |  | 
        |  | 
        
        | Term 
 
        | What are some common anticonvulsants? |  | Definition 
 
        | Barbiturates (Phenobarbital) Benzodiazepines (Klonopin, Ativan, Valium)
 Hydantoins and Phenytoin-like drugs (Dilantin, Tegretol, Depakote)
 Succinimides (Zarotin)
 |  | 
        |  | 
        
        | Term 
 
        | What are side effects of anticonvulsants? |  | Definition 
 
        | Sedation, Lethargy, drowsiness, fatigue, Dizziness, postural hypotension, Nausea, vomiting, wt loss, abdominal pain, Depletion of vitamins; folic acid, Vit D, Vit C, Gingival hypertrophy |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions of the side effects of anticonvulsants? |  | Definition 
 
        | Sedation, Lethargy, drowsiness, fatigue Safety Issues
 Avoid Alcohol
 Dizziness, postural hypotension
 Position changes slowly
 Safety issues
 Nausea, vomiting, wt loss, abdominal pain
 Take medication c food
 Depletion of vitamins; folic acid, Vit D, Vit C
 Assess for bleeding of the mucous membranes and unusual bleeding
 Gingival hypertrophy
 Frequent oral care including flossing
 |  | 
        |  | 
        
        | Term 
 
        | What are additional nursing actions for anticonvulsants? |  | Definition 
 
        | Seizure precautions Educate not to stop medication abruptly
 Immediately report changes in mood, mental depression or suicidal urges
 Monitor liver and renal functions
 |  | 
        |  | 
        
        | Term 
 
        | What are interactions for anticonvulsants? |  | Definition 
 
        | Interactions phenobarb/benzodiszepines with alcohol/CNS depressants
 Increase metabolism of other drugs with phenobarb
 Valium and Zarontin increase phenytoin levels (toxicity)
 Oral contraceptive decrease effectiveness
 Phenyotoin triggers seizures with tricyclic antidepressants
 Kava, valerian, chamomile increase effect
 |  | 
        |  | 
        
        | Term 
 
        | What are s/s sometimes associated with anxiety? |  | Definition 
 
        | Insomnia or sleeplessness |  | 
        |  | 
        
        | Term 
 
        | What are some CNS depressants? |  | Definition 
 
        | Antidepressants Benzodiazepines
 Barbiturates
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of hypnotics? |  | Definition 
 
        | attach to GABA-BZ receptors; GABA is inhibitory and calms te brain; cause sedation, reduce anxiety, skeletal muscle relaxation, anticonvulsant effects |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of hypnotics? |  | Definition 
 
        | Drowsiness, daytime sedation, amnesia, dizziness NVD
 Dependence
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of hypnotics? |  | Definition 
 
        | Drowsiness, daytime sedation, amnesia, dizziness Safety needs
 Assess dosage and time medication is given in relation to sedation during the day
 Avoid alcohol with hypnotics
 NVD
 Take with food
 Dependence
 Assess frequency of requests for Rx
 Reporting less effects from the drug
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for hypnotics? |  | Definition 
 
        | Concurrent use of CNS depressants potentiates sedation effects and increases the risk for respiratory depression Sedation-producing herbs may have an additive effect
 Stimulant herbs may reduce the effectiveness of the drug
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of anti-parkinsons? |  | Definition 
 
        | restore the balance of neurotransmitters, dopamine and acetylcholine to the brain |  | 
        |  | 
        
        | Term 
 
        | What does the loss of dopamine cause with parkinson's disease? |  | Definition 
 
        | Tremors, muscle rigidity, bradykinesia, postural instability |  | 
        |  | 
        
        | Term 
 
        | What are side effects of anti-parkinsons? |  | Definition 
 
        | Uncontrolled, purposeless movements Loss of appetite, NV
 Dry mouth
 Blurred vision
 Tachycardia
 Urine retention/constipation
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects for anti-parkinsons? |  | Definition 
 
        | Uncontrolled, purposeless movements Client safety
 Assess LOC
 Do not stop abruptly
 Loss of appetite, NV
 Frequent small meals
 Give with meals
 Dry mouth
 Frequent oral care
 Hard candy of not a safety issue
 Blurred vision
 Client safety
 Tachycardia
 Monitor VS
 Urine retention/constipation
 Monitor I&O
 Monitor bowel status
 Increase fiber and fluids
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for anti-parkinsons? |  | Definition 
 
        | Levadopa interacts with many drugs that cause decrease effects of the drug (tricyclic antidepressants, haloperidol, anticonvulsants, B6) to hypertensive crisis (MAO) or hypotension (antihypertensives) Kava worsens s/s
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of anti-alzheimer's? |  | Definition 
 
        | Intensify the effects of acetylcholine at the receptor sides ( acethycholinesterase inhibitor- Aricept, donepezil) Reduce high levels of glutamate (glutamate causes Ca+ to enter and excite neurons causing cell death-Namenda, memantine)
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of anti-alzheimer's? |  | Definition 
 
        | Parasympathetic actions; NVD Darkened urine, incontinence
 CNS effects; insomnia, syncope, depression, irritability, headache, hot flashes, increased libido
 MS effects, muscle cramps, arthritis, fractures
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions of the side effects of anti-alzheimer's? |  | Definition 
 
        | Parasympathetic actions; NVD Monitor bowel function
 Provide fluids
 Take with food
 Darkened urine, incontinence
 Monitor urine output
 Bladder training program
 CNS effects; insomnia, syncope, depression, irritability, headache, hot flashes, increased libido
 Monitor LOC
 6-months use to identify maximum benefits	MS effects, muscle cramps, arthritis, fractures
 Assess gait
 Safety issues
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for anti- alzheimer's? |  | Definition 
 
        | Cholinergic will have synergistic effects, do not administer 2 parasympathomimetics. Elimination increased with phenobarb, phenytoin, dexamethasone, rifampin
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of skeletal muscle relaxants? What are they used for?
 |  | Definition 
 
        | Cause CNS depression effects Used to treat local muscle spasms resulting from injury
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of skeletal muscle relaxants? |  | Definition 
 
        | Drowsiness, dizziness, blurred vision Dry mouth
 Rash
 Tachycardia
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of skeletal muscle relaxants? |  | Definition 
 
        | Drowsiness, dizziness, blurred vision Safety needs
 Educate to postural changes
 Dry mouth
 Offer fluids
 Hard candy
 Rash
 Monitor skin, daily assessment
 Tachycardia
 Monitor VS and report elevations of pulse
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for skeletal muscle relaxants? |  | Definition 
 
        | Do not use with other CNS depressants as will cause additive sedation Should not use within 2 weeks of a MAO
 May take up to 2-3 weeks before reach full effects
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of antispasmodics? |  | Definition 
 
        | Interferes with the release of Ca+ ions in the skeletal muscle (Dantrium, dantrolene) Or
 Blocks the release of acetylcholine (botulinum toxin)
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of antispasmodics? |  | Definition 
 
        | Muscle weakness, headache, dizziness Pain at injection site with botulinum
 Diarrhea
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of antispasmodics? |  | Definition 
 
        | Muscle weakness, headache, dizziness Safety issues
 Adjunct therapy for muscle for muscle spasms
 Ice or heat, massage, ROM
 Pain at injection site with botulinum
 Use of local anesthetic
 Assess skin at area of skin trauma
 Diarrhea
 Monitor bowel status
 Encourage fluids
 |  | 
        |  | 
        
        | Term 
 
        | What are interactions for antispasmodics? |  | Definition 
 
        | Do not take with CNS depressants, cough preparations and antihistamines Ca+ channel blocker increase risk V-fib
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions for CNS stimulants for ADHD? |  | Definition 
 
        | Causes heightened alertness the area of the brain that is associated with focus and attention Partially achieved by release of norepinephrine, dopamine serotonin
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effect of CNS Stimulants for ADHD? |  | Definition 
 
        | HTN, irregular heart beat Hepatotoxicity
 Wt loss
 Drug dependency (Schedule II)
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effect of CNS Stimulants for ADHD? |  | Definition 
 
        | HTN, irregular heart beat Periodic monitoring of VS
 Hepatotoxicity
 Monitor liver function studies
 Wt loss
 High-calorie nutritious meals
 Weigh weekly
 Drug dependency (Schedule II)
 Periodic drug-free holidays
 Assess behavior during these periods
 Keep medication in a secure location
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for CNS stimulants for ADHD? |  | Definition 
 
        | Decreases effectiveness of anticonvulsants and anticoagulants MAO may produce HTN crisis
 Other CN stimulants could increase vasoconstrictive actions
 |  | 
        |  | 
        
        | Term 
 
        | What are the three endocrine hormones that use pharmacotherapy? |  | Definition 
 
        | Growth Hormone or somatotropin ADH
 Oxytocin
 |  | 
        |  | 
        
        | Term 
 
        | What does the growth hormone (somatotropin) do? |  | Definition 
 
        | stimulates growth and metabolism in every cell. Deficiency seen in children= dwarfism |  | 
        |  | 
        
        | Term 
 
        | What does ADH (vasopressin) do in the endocrine systeem? |  | Definition 
 
        | conserves water in the body= raises B/P |  | 
        |  | 
        
        | Term 
 
        | What is oxytocin used for? |  | Definition 
 
        | induce labor; strengthen contractions |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of the growth hormones in the pituitary? |  | Definition 
 
        | Edema at injection site Allergic reactions
 Hypercalciuria
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of the growth hormones in the pituitary? |  | Definition 
 
        | Edema at injection site Application of ice at site
 Allergic reactions
 Assess for skin rash, dyspnea
 Hypercalciuria
 Encourage fluids during therapy
 |  | 
        |  | 
        
        | Term 
 
        | what are the side effects of the Vasopressin's in the pituitary? |  | Definition 
 
        | HTN Angina and MI
 Fluid retent
 |  | 
        |  | 
        
        | Term 
 
        | What are nursing actions for the side effects of the Vasopressin's in the pituitary? |  | Definition 
 
        | HTN Monitor VS especially B/P
 Assess for headaches, changes in mental status
 Compliance with lab draws
 Angina and MI
 Assess for chest pain
 Refer to HCP immediately with symptoms
 Fluid retention
 Weigh twice weekly and report significant increases or decreases
 Monitor I&O
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions (primarily with vasopressin's)  in the pituitary? |  | Definition 
 
        | Decrease effects with concurrent use of alcohol, heparin, lithium, andphenytoin Educate to contact HCP before taking any OTC or herbs
 |  | 
        |  | 
        
        | Term 
 
        | What are the pharmacotherapy's of the thyroid in the pituitary? |  | Definition 
 
        | Hypothyroidism- replace the thyroid hormone The thyroid gland controls your BMR, either up or down in function
 |  | 
        |  | 
        
        | Term 
 
        | what are the side effects of the of pharmacotherapy's in the thyroid? |  | Definition 
 
        | Replacement= s/s hyperthyroidism Palpitations, dysrrythmias, anxiety, insomnia, weight loss, heat intolerance
 Anti-thyroid= s/s hypotension, fatigue, depression, sensitivity to cold, hair loss, dry skin
 Rash and leucopenia
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of the pharmacotherapy's in the thyroid? |  | Definition 
 
        | Replacement= s/s hyperthyroidism Palpitations, dysrrythmias, anxiety, insomnia, weight loss, heat intolerance
 Monitor VS
 Take medication in the morning before eating
 Weigh weekly
 Follow up for blood work
 Monitor BS with diabetics
 Educate to compliance of drug
 Anti-thyroid= s/s hypotension, fatigue, depression, sensitivity to cold, hair loss, dry skin
 
 Rash and leucopenia
 Monitor VS
 Take medication in the morning before eating
 Weigh weekly
 Follow up for blood work
 Monitor BS with diabetics
 Educate to compliance of drug
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for the pharmacotherapy's in the thyroid? |  | Definition 
 
        | Levothyroxin Do not take within 4 hrs of other medication or vitamins
 Bile acid agent decrease absorption
 Use with warfarin causes potentiation
 Propythiouracil
 Reverses the effects of aminophyline, heparin, digoxin
 Drugs or iodine diminishes effects
 |  | 
        |  | 
        
        | Term 
 
        | What do the adrenals do in the endocrine system? |  | Definition 
 
        | Secrete steroid hormones Gonadocorticoids, androgens, estrogen post menopause
 Mineralocorticoids, aldostrerone (Na reabsorption and K+ excretion)
 |  | 
        |  | 
        
        | Term 
 
        | What will the primary pharmacotherapy be in the adrenal? |  | Definition 
 
        | Replacement with adrenal insufficiency Decrease inflammatory and immune responses
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of the primary pharmacotherapy's in the adrenal? |  | Definition 
 
        | Low doses for replacement or topical/intranasal are rare High doses and prolonged use = Cushing’s s/s
 Moon face, buffalo hump, obesity with limb wasting
 CNS effects- insomnia, anxiety, confusion, depression, increased appetite
 CV- HTN, tachycardia, edema
 Gastric upset
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of the primary pharmacotherapy's in the adrenal? |  | Definition 
 
        | Cushing’s s/s- moon face, buffalo hump, obesity with limb wasting Weigh daily
 Physical activity, weight bearing
 CNS effectors, insomnia, anxiety, confusion, depression, increased appetite
 Avoid dosing at HS
 Educate to mood changes
 Report changes to HPC
 CV-HTN, tachycardia, edema
 Monitor VS
 Assess for peripheral edema
 Follow up for lab work (lytes)
 Gastric upset
 Take with food
 Report any tarry stools or abdominal pain
 Monitor for infection
 Suppression for immune system
 Monitor lab work
 Monitor wound healing
 Impaired healing
 Monitor glucose levels
 Increased gluconeogenesis
 Report s/s hyperglycemia
 Adjust insulin doses with diabetics
 Monitor compliance of the drug
 Do not stop abruptly, taper
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for the primary pharmacotherapy's in the adrenal? |  | Definition 
 
        | Increase metabolism with barbiturates, phenytoin, rifampin Potentiation with estrogens
 NSAIDS increase gastric distress
 Increase K+ loss with diuretics
 Decrease immune response with biologicals
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | caused by genetic and environmental factors that impair the cellular utilization of glucose |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | is to assist in glucose transport into the cells, without insulin glucose cannot enter the cell; develop increase blood sugar (hopoglycemia) |  | 
        |  | 
        
        | Term 
 
        | What do the islets of langerhans secrete in the pancreas? |  | Definition 
 
        | secrete both insulin and glucose |  | 
        |  | 
        
        | Term 
 
        | How does glucagon work with insulin? |  | Definition 
 
        | Glucagon antagonist to insulin; when glucose levels are low (hypoglycemia) secrete glucose |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | autoimmune destruction of pancreatic beta cells, lack insulin secretion |  | 
        |  | 
        
        | Term 
 
        | What is type II Diabetes? |  | Definition 
 
        | insulin receptors in the target tissues have become insulin resistant. Produce insulin but at deficient amounts |  | 
        |  | 
        
        | Term 
 
        | What is the onset, peak, durations for raid-actings insulins and what are some common drugs? |  | Definition 
 
        | Onset 10-30” Peak 0.5-3 hrs
 Duration 3-6 hrs
 Common drugs: NovoLog, Humalog, Apidra
 |  | 
        |  | 
        
        | Term 
 
        | What is the onset, peak, durations for short-actings insulins and what are some common drugs? |  | Definition 
 
        | Onset 30-60” Peak 1-5 hrs
 Duration 6-10 hrs
 Common drugs: Insulin Regular
 |  | 
        |  | 
        
        | Term 
 
        | What is the onset, peak, durations for intermediate-actings insulins and what are some common drugs? |  | Definition 
 
        | Onset 1-2 hrs Peak 6-14
 Duration 16-24 hrs
 Common drugs: NPH, Humalin N)
 |  | 
        |  | 
        
        | Term 
 
        | What is the onset, peak, durations for long-actings insulins and what are some common drugs? |  | Definition 
 
        | Onset 1-2 hrs Non PEAK
 Duration 24 hrs
 Common drugs: Levemir, Lantus
 |  | 
        |  | 
        
        | Term 
 
        | What are the types of oral hypoglycemics? |  | Definition 
 
        | Sulfonylureas Biguanides
 Alpha-glucosidase inhibitors
 Thiazolidinediones
 Meglitinides
 Newer agents
 |  | 
        |  | 
        
        | Term 
 
        | How do sulfonylureas's work? |  | Definition 
 
        | Sulfonylureas- stimulate pancreatic cells increase insulin sensitivity |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Biguanides- decreases hepatic glucose and reduces insulin resistance |  | 
        |  | 
        
        | Term 
 
        | How do Alpha-Glucosidase inhibitors work? |  | Definition 
 
        | Alpha-glucosidase inhibitors- block enzymes in sm intestine responsible for breaking down complex CHO |  | 
        |  | 
        
        | Term 
 
        | How do Thiazolidinediones work |  | Definition 
 
        | Thiazolidinediones- decreases insulin resistance and inhibit hepatic glucose |  | 
        |  | 
        
        | Term 
 
        | How do Meglitinides work? |  | Definition 
 
        | Meglitinides- stimulate insulin from islet cells |  | 
        |  | 
        
        | Term 
 
        | How do Newer Agents work? |  | Definition 
 
        | Newer agents- incretin-glucose mechanism; incretins (intestines) signal insulin release and liver stop producing glucagon |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of oral hypoglycemics? |  | Definition 
 
        | Hypoglycemia NVD, anorexia, flatulence, abdominal distension
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of oral hypoglycemics? |  | Definition 
 
        | Hypoglycemia Monitor BS
 Monitor VS
 Provide meal, do not skip meals
 Simple sugar at first sign of hypoglycemia
 NVD, anorexia, flatulence, abdominal distension
 Take with food
 Monitor weight weekly
 Changes in weight leads to med changes
 Monitor activity level
 Increase activity= lower BS
 Monitor for s/s illness or infection
 May cause increase glucose levels
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for oral hypoglycemics? |  | Definition 
 
        | Drops BS with insulin and alcohol, salicylates, MAO, anabolic steroids Increase BS with Corticosteroids, thyroid, epinephrine, furosemide or thiazide diuretics both insulin and orals
 Garlic, bilberry and ginseng increase hypoglycemia
 |  | 
        |  | 
        
        | Term 
 
        | What is an ulcer and what is the primary cause? |  | Definition 
 
        | An ulcer is an erosion or the mucosa layer of the GI tract, associated with acute inflammation Primary cause H. pulori bacterium
 |  | 
        |  | 
        
        | Term 
 
        | What is GERD (gastroesophageal reflux disease)? |  | Definition 
 
        | utilizes the same meds as with peptic ulcers |  | 
        |  | 
        
        | Term 
 
        | What are the actions of ant-ulcers? |  | Definition 
 
        | relieve symptoms, promote healing, and prevent future occurrence with; HZ receptor antagonists
 Proton pump inhibitors
 Antacids
 Antibiotics
 |  | 
        |  | 
        
        | Term 
 
        | How do H2 receptor antagonists work? |  | Definition 
 
        | block H2 receptors to suppress the volume and acidity of the parietal cells secretions |  | 
        |  | 
        
        | Term 
 
        | How do Proton pump Inhibitors works? |  | Definition 
 
        | binds irreversibly to the enzyme H+ K+ ATPase to reduce stomach acid secretion |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of anti-ulcers? |  | Definition 
 
        | H2 receptors CNS effects; dizziness, drowsiness, confusion, headache primarily with elderly
 Rare Hepatotoxicity
 Vit B12 deficiency
 Proton Pump
 Headache
 Nausea, diarrhea, abdominal pain
 Rash
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of anti-ulcers? |  | Definition 
 
        | CNS effects; dizziness, drowsiness, confusion, headache primarily with elderly Safety issues
 Rare Hepatotoxicity
 Iron supplements
 Monitor CBC for anemia
 Vit B12 deficiency
 Monitor liver profile
 Nausea, diarrhea, abdominal pain
 Give 30” before meals
 Can be given at same time with antacid
 Probiotics
 Smoking and alcohol cessation will cause increase aid production
 Rash
 Assess skin observe for other s/s allergies
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for anti-ulcers? |  | Definition 
 
        | H2antagonists- decrease absorption of cefpodoxime, ketoconazole, itraconazole Smoking decreases effects
 Proton Pump- increase blood levels of diazepam, phenytoin, CNS depressants and warfarin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | neutralize the stomach acid. Decrease Ph |  | 
        |  | 
        
        | Term 
 
        | what are the side effects of antacids? |  | Definition 
 
        | Magnesium and aluminum based products may cause diarrhea Calcium based products may cause constipation
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of antacids? |  | Definition 
 
        | Monitor bowel status Medications make the stools white, educate
 Thoroughly chew tablets before swallowing
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for antacids? |  | Definition 
 
        | Do not take antacids with other meds due to the binding potential with meds Avoid preparations with sodium for clients on low sodium diet
 Do not take magnesium products when in kidney failure
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Laxatives promote the evacuation of the bowels |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of laxatives? |  | Definition 
 
        | Nausea, abdominal distention, diarrhea |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of laxatives? |  | Definition 
 
        | Assess bowel patterns Encourage fluids 2-3 L per day if not contraindicated
 Educate to follow instructions, more does not mean better
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for antacids? |  | Definition 
 
        | Bulk forming preparations can decrease absorption of drugs Osmotic preparations can alter electrolytes if overused
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of anti-diarrheals? |  | Definition 
 
        | return elimination patterns to normal, slow peristalisis Identify cause of diarrhea and treat underlying cause
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of anti-diarrheals? |  | Definition 
 
        | Dizziness, drowsiness Development of constipation
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of anti-diarrheals? |  | Definition 
 
        | Dizziness, drowsiness Safety issues
 Change position slowly
 Assess for dehydration as contributing factor
 Development of constipation
 Monitor stool patterns
 Avoid anti-diarrheals with viral infections as slowing the peristalsis keeps the virus in the body longer
 Discontinue meds once diarrhea or liquid stool stop
 Fluids
 BRAT (Bananas, rice, applesauce, tea/toast
 Electrolyte fluids for replacement
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for anti-diarrheals? |  | Definition 
 
        | Additive effects with CNS depressants St Johns Wort decreases Zofran concentration
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of anorexiants? |  | Definition 
 
        | induce weight loss by suppressing appetite and hunger Short term control of obesity, BMI 30 or greater
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of anorexiants? |  | Definition 
 
        | HTN, tachycardia, dysrhythmias Potential for dependence
 Insomnia
 Dry mouth
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of anorexiants? |  | Definition 
 
        | HTN, tachycardia, dysrhythmias Investigate history prior to stating
 Monitor VS, report sustained increases
 Potential for dependence
 Use for 12 months only
 Lifestyle modifications
 Insomnia
 Take in the morning
 Take prescribed amount
 Dry mouth
 Fluids
 Hard candy
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for anorexiants? |  | Definition 
 
        | Cough and cold medications can cause increased HTN Do not use Meridia (sibutramine) with other SSRI
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of pancreatic enzymes? |  | Definition 
 
        | replaces pancreatic enzymes when the enzymes are absent or deficient |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of pancreatic enzymes? |  | Definition 
 
        | rare Nausea, cramping, diarrhea with excess dosage
 |  | 
        |  | 
        
        | Term 
 
        | what are the nursing actions for the side effects of pancreatic enzymes? |  | Definition 
 
        | Take with meals or snacks Do not chew table but may use capsules by opening over applesauce, mashed fruit
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for pancreatic enzymes? |  | Definition 
 
        | Antacids may decrease effects Enzymes may decrease absorption of iron
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of hematoligic meds? |  | Definition 
 
        | growth factors that stimulate blood cell production Red Blood Cells with erythropoietin, epoetin alfa (Epogen) IV or subq
 White Blood Cells with colony stimulating factors for neurtophils with filgrastim (Neupogen) IV or subq
 Platelet enhancers with oprelvekin (Neumega) subq
 |  | 
        |  | 
        
        | Term 
 
        | What are the hematopoietic agents? |  | Definition 
 
        | Anti-anemic Blood products
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of hematoligic meds? |  | Definition 
 
        | Epogen- HTN, risk for thrombis, headache, fever, nausea, diarrhea, edema Neupogen- bone pain
 Neumega- NVD, fluid retention, fever, headache, dizziness
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of hematoligic meds? |  | Definition 
 
        | Begin treatments at least 24 hrs after chemotherapy Monitor VS especially temp and B/P
 Monitor lab work, CBC
 Monitor bowel status, assess for NVD
 Alternative measure for discomforts
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for hematoligic meds? |  | Definition 
 
        | Administering within 24 hrs of cemo reduces med effectiveness Enhance blood clotting, need for increase anticoagulant doses
 Increase loss of K+ with Neumega and diuretics
 |  | 
        |  | 
        
        | Term 
 
        | What are anti-anemic meds and what are their actions? |  | Definition 
 
        | vitamins or minerals given to enhance the production of the oxygen-caring capacity of the blood. RBC/Hgb |  | 
        |  | 
        
        | Term 
 
        | What are some anti-anemic meds? |  | Definition 
 
        | Cyanocobalamin (B12) B12 needs intrinsic factor form stomach to the absorbed in the intestine, absent in disease of stomach, removal of stomach
 Folic acid
 Deficiency due to insufficient dietary intake
 Ferrous sulfate
 Primary cause of iron deficiency blood loss and dietary deficiency
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of anti-anemics? |  | Definition 
 
        | Cyanocobalamin- rare, sm % rash and itchy Folic acid- uncommon
 Iron- GI upset, dark stools, constipation
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of anti-anemics? |  | Definition 
 
        | Assess injection site for rash or itching Give iron with food to decrease GI upset, with straw if liquid
 Keep iron preparation out of reach of children
 Educate to dark stools
 Encourage increase in fluids and fiver to combat constipation
 Monitor physical response to supplements
 Increase energy and less fatigue
 Improved skin color
 In children improvement in growth with growth chart
 |  | 
        |  | 
        
        | Term 
 
        | What are interactions for anti-anemics? |  | Definition 
 
        | Iron is absorbed better with orange juice Iron absorption reduced with antacids, proton-pump inhibitors or calcium supplements, also dairy
 Iron decreases absorption of antibiotics, take at least 1 hr before or after
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | A blood product is any component of the blood which is collected from a donor for use in a blood transfusion Most blood products consist of specific processed components such as red blood cells, while blood cells, blood plasma, platelets, cryoprecipitate, immune globulins
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of blood products? |  | Definition 
 
        | Incompatibility- transfusion reaction Allergic reactions
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of blood products? |  | Definition 
 
        | Meticulously check and document identification of blood component to infuse (two nurses) Give pre-infusion antihistamine
 Pre0infusion VS and q15” VS during infusion
 Most infusions given within 2 hrs
 Monitor output
 Monitor for s/s reaction
 Low lack pain
 Chills
 Dizziness
 Flushing, itching or hives
 Dyspnea
 Tachycardia
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for blood products? |  | Definition 
 
        | Second IV line for all mess Flush main IV with NS prior to infusion
 Blood warmer for central lines
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of vaccines? |  | Definition 
 
        | administration of modified, harmless microorganism or toxoid so that an immune response occurs. If future exposure quick reaction and response to produce large amounts of antibodies
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of vaccines? |  | Definition 
 
        | Redness and discomfort at the injection site Fever, malaise, headache
 Anaphylaxsis
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of vaccines? |  | Definition 
 
        | Educate to schedule and importance of compliance Reliable contraception with MMR, vericella
 Redness and discomfort at the injection site
 Encourage warm pack or soak in the tub
 Fever, malaise, headache
 Acetamenipnen prior to injection and the alternate with ibuprofen every 4 hrs for 24 hrs
 Anaphylaxsis
 Emergency epinephrine on hand
 Immediate referral to ER/HCP
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for vaccines? |  | Definition 
 
        | Do not give if client is currently sick, or weakened immune system (immune system is already compromised) Previous known allergy to vaccine or components
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of allergy shots? |  | Definition 
 
        | help the body build immunity to specific allergens decrease the risk of developing asthma by 50% and reduce the chance of developing new allergens
 contains a purified form of the allergens that are causing problems
 The dosage of the allergen in gradually increased over the first 4 to 5 months to a monthly maintenance dose, which is usually given for up to 3 yrs
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of allergy shots? |  | Definition 
 
        | Shortness of air, wheezing, anaphylaxis Redness at injection
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of allergy shots? |  | Definition 
 
        | Nursing actions Shortness of air, wheezing, anaphylaxis
 *After giving injection, have the client remain in the waiting room up to 30” or dependent upon policy
 Epinephrine on hand when administering
 Redness at injection
 Monitor
 Ice or cool pack
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for allergy shots? |  | Definition 
 
        | Steroids will decrease the immune response Allergic reaction to serum
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of immunosuppressants? |  | Definition 
 
        | dampen or suppress the immune response, suppress T-cell function Primarily utilized with organ transplants to avoid rejection, also use with autoimmune diseases
 Some of the drugs are very selective in their action and other are non-selective with more side effects
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of immunosuppressants? |  | Definition 
 
        | Hirsutism (hair between breasts), gingival hyperplasia, gynecomastia (man boobs) Hyperkalemia, leucopenia
 Nephrotoxicity
 Hepatotoxicity
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of immunosuppressants? |  | Definition 
 
        | Hirsutism, gingival hyperplasia, gynecomastia See dentist regularly
 Identify self image issues
 Wax
 Hyperkalemia, leucopenia
 *Monitor CBC and electrolytes
 Educate to follow up labs
 Nephrotoxicity
 Monitor output
 Monitor renal labs
 Hepatotoxicity
 Monitor liver function studies (creatinine)
 Assess sclera and skin color (jaundice)
 Educate to importance of lab follow up
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for immunosuppressants? |  | Definition 
 
        | Multiple drug interactions with calcineurin inhibitors Increase risk for infection
 Increase risk with side effects with vaccines and low immune response
 Do not take Echinacea as this boosts immune system
 |  | 
        |  | 
        
        | Term 
 
        | What are 4 types of immunosupressants? |  | Definition 
 
        | Antibodies- Humira (adalimumab), remicade (infliximab) Antimetabolite- Imuran (azahioprine), Enbral (eranercept)
 Calcineurin- Sandimmune (cuclosporine)
 Glucocorticoids
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions for immunostimulants? |  | Definition 
 
        | boost specific functions of the immune system Use with cancer, chronic viral infections
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of immunostimulants? |  | Definition 
 
        | Flu like s/s in 50% of clients. Headache malaise, NV, anorexia Hepatotoxicity
 Nephrotoxicity
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of immunostimulants? |  | Definition 
 
        | Flu like s/s in 50% of clients. Headache malaise, NV, anorexia Palative support care during therapy
 Hepatotoxicity
 Monitor liver function studies
 Educate to importance of lab follow-up
 Nephrotoxicity
 Monitor output
 Monitor renal studies
 Educate to importance of lab follow-up
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for immunostimulants? |  | Definition 
 
        | Bone marrow suppression with antineoplactics Antivirals may increase hematologic toxicity
 Echinacea may cause additive immune boosting properties
 |  | 
        |  | 
        
        | Term 
 
        | What do interferons (interleukins) do? |  | Definition 
 
        | Stimulates immune system to remove antigens Suppress the growth of cancer cells
 |  | 
        |  | 
        
        | Term 
 
        | What is cancer (carcinoma) characterized by? |  | Definition 
 
        | abnormal, uncontrolled cell division Primary site
 Metastasis
 Neoplasm
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of antineoplactics? |  | Definition 
 
        | kill cancer cells by interfering in their replication ability. Purpose of the drug therapy to cure, palliation or prophylaxsis |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of antineoplactics? |  | Definition 
 
        | Antineoplatics attack the fast growing cancer cells and any other cells in the body that replicate quickly Hair
 Skin of the mucous membranes, mouth and GI tract (sores in mouth and food taste funny meat taste like iron)
 Bone marrow (low RBC WBC= pale)
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of antineoplactics? |  | Definition 
 
        | Alopecia-prepare for hair loss Refer to wigs
 Open communication discussing body image
 Stomatitis , GI distress
 Antiemetics before during treatments (prevent vomiting)
 Palatable foods (whatever tastes good)
 Weigh weekly
 Viscous xylocaine for mouth sore
 Bone marrow suppression
 Weekly CBC, monitor results
 Protect from infection (*If your sick, stay away)
 Fatigue, educate to balance of work and rest
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for antineoplactics? |  | Definition 
 
        | Toxic drugs with multiple drug interactions Always check resource for interactions to prescription, OTC and herbs
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of Antirheumatics? |  | Definition 
 
        | Treatment for Rheumatoid Arthritis is a combination of drugs. Initially analgesics and anti-inflammatory Disease modifying antirheumatic work to decrease the autoimmune response in the body by suppressing formation of the antigens for the immune reaction in the body
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of Antirheumatics? |  | Definition 
 
        | GI- anorexia, NV Headache, personality changes
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of Antirheumatics? |  | Definition 
 
        | Full Effects of the drug may not be evident for 6 months Compliance with dosing (be patient)
 GI- anorexia, NV
 Give with food
 Headache, personality changes
 Assess changes and refer for significant changes to HCP
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for Antirheumatics? |  | Definition 
 
        | Antacids with aluminum and magnesium will alter absorption Increase digoxin level if concurrent use
 Increase over toxicity with other hepatotoxic drugs
 No Alcohol= dizziness and blurred vision
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Gout is a form of acute or chronic arthritis due to an accumulation of uric acid crystals. Primary gout the client cannot metabolize uric acid |  | 
        |  | 
        
        | Term 
 
        | What are the actions of antigouts? |  | Definition 
 
        | block the accumulation of uric acid in the blood |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of antigouts? |  | Definition 
 
        | GI upset, NVD Bone marrow toxicity with colchicine
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of antigouts? |  | Definition 
 
        | GI upset, NVD Take on an empty stomach
 Avoid concurrent with NSAIDS
 Must drink 3-4L of fluids daily
 Bone marrow toxicity with colchicine
 Monitor blood values (CBC)
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for antigouts? |  | Definition 
 
        | Allopurinol will increase warfarin effects (increased bleeding) Thiazide diuretics less effective with allopurinol
 -Mycin drugs with cochicine can become toxic
 Limit foods that become more alkaline (dairy) leading to kidney stones
 ASA and Vit C can enhance kidney stone formation
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of antiacne agents? |  | Definition 
 
        | of OTC and prescription drugs is to decrease the sebum production along with a cleansing program |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of antiacne agents? |  | Definition 
 
        | Drying of the mucous membranes, eyes, mouth/lips, nose Elevation of triglycerides
 Photosensitivity
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of antiacne agents? |  | Definition 
 
        | Drying of the mucous membranes, eyes, mouth/lips, nose Eye lubricant drops
 Hard candy
 Lip balm
 Elevation of triglycerides
 Monitor liver function
 Monitor lipids
 Photosensitivity
 Use of sunscreen
 Wear long sleeves, hat
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for antiacne agents? |  | Definition 
 
        | Teratogen, must use contraception during course of therapy Vit A increases effectors causing toxicity
 Concurrent with hypoglycemics affects BS control
 Avoid alcohol as will increase triglycerides
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Psoriasis is a chronic inflammatory disorder of the skin where the epithelium has an extremely fast turn overrate, formation of silvery plaques |  | 
        |  | 
        
        | Term 
 
        | What are the actions of psoriasis agents? |  | Definition 
 
        | of the agents are to reduce the inflammation, plaques and improve the integrity of the skin with the use of glucocorticoids and immunomodulators |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for psoriasis? |  | Definition 
 
        | Support and educate Altered self-image
 Infection control related to open skin lesions
 Compliance with meds
 |  | 
        |  | 
        
        | Term 
 
        | What are scabies and lice? How are they contracted?
 |  | Definition 
 
        | Scabies and Lice are skin parasites Contracted thru direct contact or a fomite
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of scabicides/perdiculocides? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the side effects of scabicides/perdiculocides? |  | Definition 
 
        | Skin irritation, burning, stinging, itching, swelling Lindane can have systemic effects of dizziness, tremors, convulsions
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of scabicides/perdiculocides? |  | Definition 
 
        | RID and NIX apply to dry hair or skin for 10” then wet and lather Skin irritation, burning, stinging, itching, swelling
 Rinse produce off the skin and report to HCP
 Lindane is applied to skin 8-12 hrs them washed off. Do not use with children
 Lindane can have systemic effects of dizziness, tremors, convulsions
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for scabicides/perdiculocides? |  | Definition 
 
        | Do not use NIX or RID if allergic to chrysanthemums Do not use RID if allergic to ragweed
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | a dysfunction of neurotransmitters |  | 
        |  | 
        
        | Term 
 
        | What are the actions of Antidepressants? |  | Definition 
 
        | Block enzymatic breakdown of norepinephrine Slow the reuptake of seratonin
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of Antidepressants? |  | Definition 
 
        | Drowsiness, somnolence, sedation, dizziness, fatigue Orthostatic hypotension, blurred vision, headache
 Dry mouth, GI disturbances, constipation, anorexia and increase appetite
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of Antidepressants? |  | Definition 
 
        | *Education that antidepressants do not reach full therapeutic effect for 3-4 week Need for psychotherapy in addition to pharmacotherapy
 Drowsiness, somnolence, sedation, dizziness, fatigue
 Safety issues
 Periods of rest with activity
 Orthostatic hypotension, blurred vision, headache
 Change positions slowly
 Dry mouth, GI disturbances, constipation, anorexia and increase
 appetite
 Take at HS
 Increase fluids
 Weigh weekly
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for Antidepressants? |  | Definition 
 
        | Tricyclic do not take with other CNS meds SSRI, digoxin and warfarin should be avoided as increase effects
 No St John’s Wort with antidepressants
 MAO cannot be given concurrently with other antidepressants. Must have 2-3 weeks between starting or ending another class
 MAO dietary restrictions- no tyramine= acute HTN
 |  | 
        |  | 
        
        | Term 
 
        | What are the types of antidepressants? |  | Definition 
 
        | Tricyclic SSRI
 MAO inhibitor
 Atypical
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | inhibit the reuptake of norepinephrine and serotonin (increase in sympathetic system) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | inhibit the reuptake of serotonin |  | 
        |  | 
        
        | Term 
 
        | How do MAO inhibitors work? |  | Definition 
 
        | decreases the effectiveness of the enzyme monamine oxidase; thus limit the destructions of norepinephrine, dopamine and serotonin (lots of side effects and reacts with a lot of food et other meds) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | inhibits the reuptake of serotonin and also affects norepinephrine and dopamine |  | 
        |  | 
        
        | Term 
 
        | What the the actions of mood stabilizers? |  | Definition 
 
        | Unsure of action but it alter activity of the neurons containing norepinephrine, dopamine and serotonin, Prevent mood swings |  | 
        |  | 
        
        | Term 
 
        | What drugs are used for mood stabilizers? |  | Definition 
 
        | Lithium (Eskalith) traditional treatment Unlabeled use of anticonvulsants has been used
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of mood stabilizers |  | Definition 
 
        | Headache, lethargy, fatigue, recent memory loss, muscle weakness NVD, anorexia, abdominal pain, dry mouth
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of mood stabilizers? |  | Definition 
 
        | Monitor blood values every 1-3 days initially then every 2-3 months Educate to compliance with med and lab follow-up
 Monitor mental status
 Headache, lethargy, fatigue, recent memory loss, muscle weakness
 Works like a salt increase loss of fluids= toxicity
 Monitor weight and fluid balance
 NVD, anorexia, abdominal pain, dry mouth
 Take with food
 Monitor electrolytes, renal status
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for mood stabilizers? |  | Definition 
 
        | Diuretics and NSAIDs increase concentration, risk for toxicity Phenothiazides may mask early signs of toxicity
 Alcohol potentiates the drug action
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of major tranquilizers? What are the goals of major tranquilizers?
 |  | Definition 
 
        | Antipsychotic meds compete for the dopamine receptor sites. Theory that there is an overabundance of dopamine at the receptor sites 
 The goal of the drug to reduce the symptoms of schizophrenia, and psychotic and irrational behaviors
 |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of major tranquilizers? |  | Definition 
 
        | Sedation, dizziness, drowsiness, orthostatic hypotension Extrapyramidal symptoms
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of major tranquilizers? |  | Definition 
 
        | Sedation, dizziness, drowsiness, orthostatic hypotension Client with schizophrenia do not like the sedated feeling, monitor compliance
 Safety issues with elderly, half dose
 Educate to slow postural changes
 Extrapyramidal symptoms
 Assess for s/s and report to HCP
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for major tranquilizers? |  | Definition 
 
        | Many drug interactions with this group Avoid any CNS depressants
 With trycyclic antidepressants elevation of B/P
 Anticonvulsants lower seizure threshold
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of urinary analgesics? |  | Definition 
 
        | Relieves urinary burning and pain |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of urinary analgesics? |  | Definition 
 
        | GI disturbances, rash, pruritis |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of urinary analgesics |  | Definition 
 
        | Give with meals Teach about reddish orange color of urine
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for urinary analgesics? |  | Definition 
 
        | Interferes with UA tests related to color reactions Urinary antiseptic & urinary antimicrobial
 Limited to treatment of UTI, drug action in the renal tubule and bladder dependent upon drug dose may be bacterialstatic or bacterialcidal
 |  | 
        |  | 
        
        | Term 
 
        | What are urinary analgesics groups? |  | Definition 
 
        | Nitrofurantoin (Macrodantin) Methenamine (Mandelamine, Hipex)
 Trimethoprim-sulfamethoxazole )Bactrim, Septra)
 Fluoroquinolones (Cipro)
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of urinary atiseptics/antimicrobials? |  | Definition 
 
        | Limited to treatment of UTI, drug action in the renal tubule and bladder dependent upon drug dose may be bacterialstatic or bacterialcidal |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of  urinary atiseptics/antimicrobials? |  | Definition 
 
        | GI disturbances: NVD Photosensitivity
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of  urinary atiseptics/antimicrobials? |  | Definition 
 
        | GI disturbances: NVD Give with meals
 Probiotics during treatment
 Increase fluids to 3000mL/day
 Photosensitivity
 Sunscreen
 Long sleeve clothing and hat
 |  | 
        |  | 
        
        | Term 
 
        | What are some common urinary antiseptic & urinary antimicrobial? |  | Definition 
 
        | Nitrofurantoin (Macrodantin) Methenamine (Mandelamine, Hipex)
 Trimethoprim-sulfamethoxazole )Bactrim, Septra)
 Fluoroquinolones (Cipro)
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of antispasmotics? |  | Definition 
 
        | direct action on the smooth muscle of the bladder, to relax, decrease urinary urgency |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of antispasmotics? |  | Definition 
 
        | Dry mouth, intestinal distention, constipation Increased heart rate, dizziness
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of antispasmotics? |  | Definition 
 
        | Dry mouth, intestinal distention, constipation Increase fluids
 Monitor bowel status
 Increased heart rate, dizziness
 Monitor VS especially B/P
 Educate to change position slowly
 Safety issues
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for antispasmotics? |  | Definition 
 
        | Mycins and – conazoles may increase the drug concentrations Meds with anticholinergic effects (antihistamines) may increase the anticholingergic effects
 Do not give to clients with glaucoma
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV solutions that contain electrolytes and other agents that mimic the body’s extracellular fluid These fluids can quickly diffuse across membranes
 |  | 
        |  | 
        
        | Term 
 
        | What are the 3 types of fluids? |  | Definition 
 
        | Isotonic (NS, LR) Hypotonic (1/2NS)
 Hypertonic (D5NS)
 |  | 
        |  | 
        
        | Term 
 
        | What are the elecrtrolytes? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Major extracellular electrolyte, regulates body fluids 135-145 mEq/L
 Water follows sodium
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Intracellular electrolyte, for transmission and conduction of nerve impulses 3.5-5.3 mEq/L
 Poorly stored in the body
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Equal intracellular and extracellular, promotes nerve and muscle activity, increases heart contraction, blood clotting 4.5-5.5 mEq/L
 Need Vit D to absorb calcium
 |  | 
        |  | 
        
        | Term 
 
        | When do electrolytes need to be replaced? |  | Definition 
 
        | when there is a hypostate Vomiting , diarrhea, renal failure
 |  | 
        |  | 
        
        | Term 
 
        | What are the routes for electrolyte admin? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the side effects of electrolytes? |  | Definition 
 
        | GI distress, diarrhea, constipation |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of electrolytes? |  | Definition 
 
        | Give with meals Monitor bowel patterns
 Accurate dosing when given IV
 Assess IV site to avoid phlebitis and infiltration
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions contraceptives? |  | Definition 
 
        | to interrupt the menstrual cycle by causing anovulation, ill prepared uterine lining, and alter cervical mucous for sperm penetration |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of contraceptives? |  | Definition 
 
        | Nausea, abdominal cramps Edema, breast tenderness, weight gain
 Fatigue
 Thromboembolic disorders with smokers or client with HTN
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing actions for the side effects of contraceptives? |  | Definition 
 
        | Encourage to take at the same time everyday, if missed back-up contraceptive method for cycle Nausea, abdominal cramps
 Take at HS
 Edema, breast tenderness, weight gain
 Monitor fluid retention
 Fatigue
 Educate as fatigue is related to adjustment of progesterone
 Thromboembolic disorders with smokers or client with HTN
 Educate to risks
 Investigate options to other methods
 |  | 
        |  | 
        
        | Term 
 
        | What are the interactions for contraceptives? |  | Definition 
 
        | Antibiotics decrease effectiveness of birth control. Recommend back up method during cycle of antibiotics BC have a decrease effect on warfarin
 |  | 
        |  | 
        
        | Term 
 
        | What are the actions of hormone replacements? |  | Definition 
 
        | to replace female reproductive hormone due to surgical or natural menopause. Supplement hormones during periods of infertility and childbearing Post menopause hormone replacement may be utilized for CV protection, osteoporosis protection or symptoms of menopause
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        | Term 
 
        | What are the side effects of hormone replacements? |  | Definition 
 
        | Breakthrough bleeding, spotting, breast tenderness, weight gain |  | 
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        | Term 
 
        | What are the nursing actions for the side effects of hormone replacements? |  | Definition 
 
        | Encourage documenting on a calendar bleeding patterns Medication requires time to regulate
 Educate that side effects due to increase hormones as with pregnancy
 Encourage not to smoke
 Monitor for thrombolytic disease
 Monitor BS as estrogen may increase levels
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        | Term 
 
        | What are the interactions for hormone replacements? |  | Definition 
 
        | Hormones decrease the effects of warfarin Contraindicated with women with estrogen sensitive breast cancer
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        | Term 
 
        | What two groups of drugs affect the uterus? |  | Definition 
 
        | Oxytocics- action to cause uterine contractions Tocolytics- action to relax and prevent uterine contractions
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        | Term 
 
        | What are the actions of the drugs that management of uterine contractions? |  | Definition 
 
        | Management of pre-term or term labor |  | 
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        | Term 
 
        | What are the side effects with management of uterine contractions? |  | Definition 
 
        | Oxytocics- hyperstimulation of the uterus, NV, uterine rupture Tocolytics- nervousness, tremors tachycardia with palpitations
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        | Term 
 
        | What are the nursing actions for the side effects with management of uterine contractions? |  | Definition 
 
        | Oxytocics- hyperstimulation of the uterus, NV, uterine rupture Fetal monitoring continuous
 Nenpharm pain relief measures
 Tocolytics- nervousness, tremors tachycardia with palpitations
 Fetal monitoring continuous at initial drug therapy, the intermittent
 Educate to common side effects
 Educate to fetal development; uterus is the best incubator
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        | Term 
 
        | What are the interactions with management of uterine contractions? |  | Definition 
 
        | Contraindicated in antepartum complications: breech, CPD, placenta previa HTN when used with vasoconstrictors or ephedra
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        | Term 
 
        | What are the actions of androgens? |  | Definition 
 
        | Produced in the testicle in men and small amounts form the adrenal in women Prescribed in disorders of hypogonadism to replace or supplement testosterone levels
 Males who lack testosterone experience erectile dysfunction, low sperm count, decreased libido
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        | Term 
 
        | What are the side effects of androgens? |  | Definition 
 
        | Increase libido, masculine features, edema, Hypercholesterolemia
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        | Term 
 
        | What are the nursing actions for the side effects of androgens? |  | Definition 
 
        | Rotate site of using injection preparation Apply patch to areas without hair
 Monitor VS especially B/P
 Monitor lipid profile
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        | Term 
 
        | What are the interactions for androgens? |  | Definition 
 
        | Contraindicated for men with diagnosis of prostate or breast cancer Caution in men with renal or hepatic disease
 Caution in men with renal or hepatic disease
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        | Term 
 
        | What are antiprostatic agents used for? |  | Definition 
 
        | for the condition called BPH (Benign Prostate Hyperplasia) the condition develops for men in their 5-6th decade, where the prostate gland enlarges, impeding urinary flow |  | 
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        | Term 
 
        | What are the actions for antiprostatic agents? |  | Definition 
 
        | alpha-adrenergic blockers is to relax smooth muscles of the prostate bladder neck and urethra (Flomax, Hytrin) Alpha-reductase inhibitors interfere with testosterone metabolism, eliminating the signal for growth of the prostate (Avadart, Proscar)
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        | Term 
 
        | What are the side effects for  antiprostatic agents? |  | Definition 
 
        | Alpha adrenergic blockers= orthostatic hypotension, headache, dizziness Alpha-reductase inhibitors= sexual dysfunction, decreased libido, decrease ejaculation volume
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        | Term 
 
        | What are the nursing actions for the side effects for  antiprostatic agents? |  | Definition 
 
        | Have men over 50 have PSA done yearly Alpha adrenergic blockers= orthostatic hypotension, headache, dizziness
 Monitor VS especially B/P and HR
 Educate to change positions slowly
 Take med at bedtime
 Alpha-reductase inhibitors= sexual dysfunction, decreased libido, decrease ejaculation volume
 Report to HCP side effects
 Women do not touch drug, teratogen to fetus
 Semen should be avoided, use a barrier method
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        | Term 
 
        | What are the interactions for antiprostatic agents? |  | Definition 
 
        | Anticholinergics will decrease effects of (Proscar) finasteride |  | 
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        | Term 
 
        | What are the actions of erectile dysfuntion meds? |  | Definition 
 
        | enhance of the erection caused by physical contact, relaxing the smooth muscle of the corpus cavenosum= increased blood flow and longer erection (vasodilation) |  | 
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        | Term 
 
        | What are the side effects of erectile dysfunction meds? |  | Definition 
 
        | Headache, flushing, nasal congestion, chest pain Diarrhea, dyspnea, dyspepsia, indigestion
 UTI
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        | Term 
 
        | What are the nursing actions for the side effects of erectile dysfunction meds? |  | Definition 
 
        | Headache, flushing, nasal congestion, chest pain Reminder the drug causes generalized vasodilation
 Do not take with nitrates
 Monitor B/P
 Diarrhea, dyspnea, dyspepsia, indigestion
 Do not take with meals, especially high fat meal, as will lower effectiveness
 UTI
 Void after coitus
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        | Term 
 
        | What are causes for erectile dysfunction? |  | Definition 
 
        | Physiologic changes Psychogenic
 Side effects of drugs
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        | Term 
 
        | What are the actions of antihistamines? |  | Definition 
 
        | block the actions of histamine at the H1 receptor Histamine is released when exposed to an allergen, Causing itching, sneezing, watery eyes
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        | Term 
 
        | What are the side effects of antihistamines? |  | Definition 
 
        | Drowsiness, anticholinergic effects- dry mucous membranes, urinary hesitancy |  | 
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        | Term 
 
        | What are the nursing actions for the side effects of antihistamines? |  | Definition 
 
        | Drowsiness, anticholinergic effects- dry mucous membranes, urinary hesitancy Avoid driving or using heavy machinery
 Take dosage as prescribed
 Hard candy
 Report to HCP urinary/voiding difficulties
 Avoid smoking or lg amounts of caffeine
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        | Term 
 
        | What are the interactions for antihistamines? |  | Definition 
 
        | Taking with other drugs of class may increase anticholinergic side effects Do not take with CNS depressants, increased sedation
 Contraindicated with glaucoma and BPH
 Stop 4 day prior to allergy test to avoid false-neg results
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        | Term 
 
        | What are the actions of decongestants? |  | Definition 
 
        | stimulates alpha adrenergic receptors in the sympathetic system. Constriction of arterioles |  | 
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        | Term 
 
        | What are the side effects for decongestants? |  | Definition 
 
        | Nasal route= nasal dryness, stinging Oral route= generalized vasoconstriction with elevated B/P and CNS excitement
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        | Term 
 
        | What are the nursing actions for the side effects for decongestants? |  | Definition 
 
        | Nasal route= nasal dryness, stinging Use only 3-5 days, development of rebound congestion
 Do not take with antihistamine
 Oral route= generalized vasoconstriction with elevated B/P and CNS excitement
 No not take at HS
 Report to HCP chest pain, numbness or tingling or the face, insomnia, sever headache, confusion
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        | Term 
 
        | What are the interactions for decongestants? |  | Definition 
 
        | Sympathomimetics use only with HCP direction with HTN, diabetes, heart disease |  | 
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        | Term 
 
        | What are the actions of antitussives? |  | Definition 
 
        | to relieve cough Work in the cough center to raise the cough threshold
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        | Term 
 
        | What are the side effects of antitussives? |  | Definition 
 
        | Dizziness, drowsiness and GI upset |  | 
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        | Term 
 
        | What are the nursing actions for the side effects of antitussives? |  | Definition 
 
        | Dizziness, drowsiness and GI upset Safety needs
 Take with food
 Cough is a protective measure to cleanse lungs, use in moderation
 If cough persists more than 3 days see HCP
 Avoid pulmonary irritants
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        | Term 
 
        | What are the interactions for antitussives? |  | Definition 
 
        | Avoid alcohol, additive effect of CNS depression Additive effects with OTC cold meds, consult HCP
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        | Term 
 
        | What are the actions of expectorants? |  | Definition 
 
        | increase mucous secretions reducing the thickness of secretions |  | 
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        | Term 
 
        | What are the side effects of expectorants? |  | Definition 
 
        | Rare expectorant effects: NV |  | 
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        | Term 
 
        | What are the nursing actions for the side effects of expectorants? |  | Definition 
 
        | Expectorants- give with water Respiratory assessment prior to and following treatment
 Assess respiratory status, sputum and report changes
 Encourage cough, deep breathing
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        | Term 
 
        | What are the actions of mucolytics? |  | Definition 
 
        | loosen thick mucous and break it down |  | 
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        | Term 
 
        | What are the side effects of mucolytics? |  | Definition 
 
        | throat irritation, NV, unpleasant odor |  | 
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        | Term 
 
        | What are the actions for bronchodialators? |  | Definition 
 
        | dilate or open the airways |  | 
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        | Term 
 
        | What are the side effects of bronchodialators? |  | Definition 
 
        | Headache, dizziness, tremors, nervousness, dry mouth, throat irritation |  | 
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        | Term 
 
        | What are the nursing actions for the side effects of bronchodialators? |  | Definition 
 
        | Headache, dizziness, tremors, nervousness, dry mouth, throat irritation Educate to prior use of MDI
 Headache, dizziness, tremors, nervousness, dry mouth, throat irritation
 Limit use of caffeine
 Rinse mouth after use
 Take med as prescribed, report unsatisfactory relief of symptoms
 Report changes in urinary pattern with elderly
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        | Term 
 
        | What are the interactions for bronchodialators? |  | Definition 
 
        | Concurrent use of beta-blockers will inhibit bronchodilation effect Use other anticholinergics will have additive effects
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        | Term 
 
        | What are the actions of inhaled glucocorticoids? |  | Definition 
 
        | used for long term prevention of asthma attacks, avoid the use of systemic steroids |  | 
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        | Term 
 
        | How do glucocorticoids work? |  | Definition 
 
        | decrease the inflammatory response to the bronchioles without major side effects |  | 
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        | Term 
 
        | What are the side effects of inhaled glucocorticoids? |  | Definition 
 
        | Hoarseness, dry mouth, cough, sore throat Candidiasis of the mouth (thrush)
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        | Term 
 
        | What are the nursing actions for the side effects of inhaled glucocorticoids? |  | Definition 
 
        | Hoarseness, dry mouth, cough, sore throat Candidiasis of the mouth (thrush)
 Rinse mouth after use
 Use as prescribed, not for use during acute attack
 Assess for s/s of infection of illness
 Monitor BS if diabetic, can raise blood sugars
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