Term
|
Definition
sum of the filtration rates in all of the functioning nephrons
can't be directly measured - must use a filtration marker like creatinine, inulin, or cystatin C |
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Term
|
Definition
the amount of nitrogen in the blood in the form of urea
an indirect and rough measurement of renal function
GFR and creatinine are better markers for kidney function |
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Term
|
Definition
Dehydration
Hypovolemia
Shock
CHF
MI
GI bleed
protein supplementation
starvation |
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Term
|
Definition
Glomerulonephritis
Pyelonephritis
Acute tubular necrosis |
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Term
|
Definition
| Ureteral or bladder outlet obstruction |
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Term
|
Definition
Liver failure
Overhydration
Negative nitrogen balance
Pregnancy - increased water retention
Nephrotic syndrome - losing protein in the urine |
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Term
|
Definition
catabolic product of creatine phosphate
excreted entirely by the kidneys
levels increase in abnormal renal function and Rhabdomyolysis
levels decrease in debilitation and decreased muscle mass |
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Term
|
Definition
Prerenal - greater than 20:1
Postrenal or normal - 10-20:1
Renal - less than 10:1 |
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Term
|
Definition
a measure of the GFR
proportional to GFR
normal male - 120 mL/min
normal female - 100 mL/min |
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Term
|
Definition
(140-age) x lean body weight / Cr x 72
if female - x 0.85
measures creatinine clearance |
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Term
|
Definition
normal is 0-8 mg/dL
trace : 15-30
1+ : 30-100
2+ : 100-300
3+ : 300-1000
4+ : >1000 |
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Term
|
Definition
Further workup required if significantly abnormal once or mildly abnormal 3 times
collect a 24 hour urine sample
normal is around 150 mg/24 hr
nephrotic is greater than 3500 mg/24 hr
glomerular cause is usually a protein:Cr of greater than 3 |
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Term
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Definition
| Clumps of material or cells that form in the renal distal and collecting tubules |
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Term
|
Definition
| Glomerulonephritis or vasculitis |
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Term
|
Definition
| tubulointerstitial disease or acute pyelonephritis |
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Term
|
Definition
| Acute tubular necrosis or acute glomerulonephritis |
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Term
|
Definition
| nephrotic syndrome or nephrosis associated with significant proteinuria |
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Term
|
Definition
May represent degenerating cellular cast
can be seen after exercise |
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Term
|
Definition
| indicitive of advanced renal failure |
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Term
|
Definition
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Term
|
Definition
| Dx of stones or ethylene glycol |
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Term
|
Definition
| Dx of treatment of malignant lymphoma |
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Term
|
Definition
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Term
|
Definition
UNa x PCr / PNa x UCr
less than 1% - prerenal disease
1 and 2% - either disorder
greater than 2% - ATN |
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Term
|
Definition
| Persistent proteinuria > 500 mg/day |
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Term
| Nephritic glomerular disease |
|
Definition
Inflammation on histologic exam
RBC casts |
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|
Term
| Nephrotic glomerular disease |
|
Definition
| Not associated with inflammation on histologic exam |
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