1. Class: Lipid-lowering, Statins
2. Action: decreases LDL, increases HDL
3. Adverse effects: Rhabdomyolysis (report muscle pain), GI discomfort
4. Contraindications: Hepatic, renal, pregnancy
5. Interactions: digoxin (increases toxicity), Grapefruit juice (may increase risk of myopathy/rhabdomyolysis
6. Labs: Liver, triglyceride, total cholesterol, HDL, LDL

cholestyramine (Questran)

1. Class: Lipid-lowering, Bile-Acid Binding Agents
2. Action: binds to bile acids containing cholesterol
3. Adverse effects: Obstruction (check bowel sounds), GI discomfort, esophageal irritation (mix w/ non-carbonated foods/beverages)
4. Contraindications: GI diseases, pregnancy
5. Interactions: Administer meds 2h before and 4h after, binds digoxin, warfarin
6. Labs: triglycerides, total cholesterol, LDL, HDL

gemfibrozil (Lopid)

1. Class: Lipid-lowering
2. Action: decreases VLDL, increases HDL
3. Adverse effects: GI discomfort
4. Contraindications: lhepatic, renal, biliary
5. Interactions: increases effects of anticoagulates = bleeding
6. Labs: triglycerides, total cholesterol, LDL, HDL

1. Class: vitamin, lipid-lowering drug
2. Action: decreases LDL
3. Adverse effects: flushing, hot flashes (take aspirin 30m before)
4. Contraindications: hepatic impairment, hypotension, bleeding, pregnancy
5. Interactions: Increases anti-hypertensives
6. Labs: triglycerides, total cholesterol, LDL, HDL

Hydrochlorothiazide (HydroDiuril)

1. Class: Thiazide Diuretic
2. Action: Reduces blood vol, Na intake, Anti-hypertensive, used for CHF
3. Adverse effects: orthostatic hypotension, dehydration
4. Contraindications:
5. Interactions: Eat potassium-rich foods
6. Labs: K⁺≤ 3.5 HOLD
7. B/P ≤ 90/60 HOLD
8. Administer EARLY to avoid nocturesis

furosemide (Lasix)

1. Class: Loop diuretic
2. Action: prevents reabsorption of Na, Cl ; anti-hypertensive ; used for CHF
3. Adverse effects: orthostatic hypotension, dehydration
4. Contraindications:
5. Interactions: Eat potassium-rich foods
6. Labs: K⁺≤ 3.5 HOLD
7. B/P ≤ 90/60 HOLD
8. Administer EARLY to avoid nocturesis

spironolactone (Aldactone)

1. Class: Potassium-sparing diuretic
2. Action: Promotes Na, Cl secretion w/o K, Anti-hypertensive, used for CHF
3. Adverse effects: Dehydration, Orthostatic hypotension
4. Contraindications: Renal failure
5. Interactions: Do not eat potassium-rich foods
6. Labs: K⁺ ≥ 5.0 HOLD
7. B/P ≤ 90/60 HOLD
8. Administer EARLY to avoid nocturesis

nifedipine (Procardia)

1. Class: Calcium Channel Blocker
2. Action: Anti-hypertensive
3. Adverse effects: hypotension
4. Contraindications: N/A
5. Interactions: Grapefruit juice, ginseng, St. John's wort
6. Labs: BGL (diabetics)
7. B/P ≤ 90/60 HOLD, AP ≤ 60 HOLD
8. Do not D/C suddenly (taper off)
9. Monitor for bleeding gums

1. Class: Calcium Channel Blockers
2. Action: Anti-hypertensive, Anti-arrhythmic
3. Adverse effects: bradycardia, tachycardia, hypotension, edema, CHF
4. Contraindications: pregnancy
5. Interactions: Grapefruit juice, St. John's wort
6. Labs: hepatic, kidney
7. B/P ≤ 90/60 HOLD, AP ≤ 60 HOLD
8. Monitor I & O