Shared Flashcard Set

Details

Cardiology
Metabolic Syndrome
18
Medical
Graduate
09/19/2010

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Cards

Term
increased abdominal circumference
Definition
What is the predominant presentation for a person with metabolic syndrome?
Term
LDL-C
Definition
Metabolic Syndrome is an at risk group with factors other than what?
Term
LDL-C
Definition
If a pt has metabolic syndrom and high LDL-C, what should you worry about fixing first?
Term

males >40

 

females >35

Definition
A risk factor for metabolic syndrome is having a waist circumference above what for males and females?
Term
>150 mg/dl
Definition
TG over what is considered a risk factor for metabolic syndrome?
Term
>110
Definition
Fasting glucose over what is a risk factor for metabolic syndrome?
Term
DM II
Definition
What has the same equivalence to a Coronary event when establishing risk for metabolic syndrome?
Term
insulin resistance
Definition
What is the etiology for metabolic syndrome?
Term
adipose
Definition
With metabolic syndrome the hallmark of the problem is storage of too much what?
Term
FFA's
Definition
In the liver, _____ result in an increased production of glucose, triglycerides and secretion of very low density lipoproteins (VLDLs).
Term
FFA's
Definition
What are released in abundance from an expanded adipose tissue mass?
Term
insulin
Definition
 ñFFAs also reduce ______ sensitivity in muscle by inhibiting insulin-mediated glucose uptake.
Term
hyperinsulinemia
Definition
Increases in circulating glucose, and to some extent FFA, increase pancreatic insulin secretion, resulting in what?
Term
insulin
Definition
 Increased plasma _____ levels are a diagnostic clue to presence of Metabolic syndrome 
Term
sodium
Definition
Hyperinsulinemia and hyperglycemia may result in enhanced _____ reabsorption and increased sympathetic nervous system (SNS) activity
Term

fibrinogen

 

plasminogen activator inhibitor 1

Definition
Cytokines and FFAs also increase the hepatic production of _____ and adipocyte production of _________ resulting in a prothrombotic state
Term
C-reactive protein
Definition
Higher levels of circulating cytokines also stimulate the hepatic production of what?
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