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Cardiology
Atherosclerosis
14
Medical
Graduate
09/19/2010

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Term
Atherosclerosis
Definition
Progression of intimal lipid deposits leading to fibrosis, smooth muscle hyperplasia, and calcification.
Term
proteoglycans
Definition
Lipoprotein particles often associate with constituents of the extracellular matrix, notably what part?
Term
collagen
Definition
Patients with genetically determined alteration of _______ metabolism develop aneurysmal dilatation of arteries rather than stenosis
Term
Fundoscopic Exam - looking for retinal arts. that may be occluded
Definition
What is a safe non-invasive, inexpensive means of diagnosing atherosclerosis on physical exam?
Term
LDL-C
Definition
Management of what has been proven to lower the incidence of ASCVD mortality and morbidity.
Term
C-reactive protein (CRP)
Definition
________ is a plasma protein, an acute phase protein produced by the liver a substance in the serum of patients with acute inflammation that reacted with the “C” polysaccharide of pneumococcus.
Term
C-reactive protein
Definition
What is an inflammatory marker and an ASCVD marker?
Term
endothelial dysfunction
Definition
Lack of physiologic control of arterial and arteriolar dilatation by the endothelium is loosely categorized as what?
Term
Nitric Oxide
Definition
Endothelium is at the helm of the artery as it controls much of the muscular activity by releasing ________, a potent vasodilator.
Term
Statins
Definition
What types of drugs minimize endothelial dysfunction?
Term
septic shock
Definition
Cytokines and endotoxins would lead you to think of what, which leads to endothelial dysfunction?
Term
Erectile dysfunction
Definition
__________ in men without significant arterial stenosis is a form of endothelial dysfunction
Term
erectile dysfunction
Definition
Statins can help with almost every type of endothelial dysfunction except what?
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