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cardio physiology
CVM
30
Medical
Graduate
03/04/2010

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Cards

Term
what is the cardiac cycle divided into?
Definition
2 cycles: systole and diastole
Term
what is systole?
Definition
the period of time when the heart is contracting, about .27 sec (half the length of diastole) which is .5 isometric contraction (short - both mitral and aortic are closed), and .22 sec ejection
Term
what is diastole?
Definition
the time, .53 sec, when the heart is relaxing which is devided into filling (.41 sec) and atrial systole (during ventricular diastole, .11 sec)
Term
what is the ejection fraction?
Definition
ejection fraction (Ef) is the fraction of the end-diastolic volume that is ejected with each beat - that is, it is stroke volume (SV) divided by end-diastolic volume (EDV) - usually 50-60% of end diastolic volume
Term
how does the heart relax?
Definition
passively, due to low (possibly negative in high heart rates) pressure (not generated by the venous system, but generated instrinsically)
Term
how do skeletal and cardiac muscles differ in terms of response to stimulus?
Definition
skeletal muscle contracts upon stimulation, and if stimulation is removed it will remain in that position. with cardiac muscle, as soon as the stimulus is removed, it will return to its original position (this is how the structure of the heart re-expands - not by venous pressure)
Term
what is blood volume like in the heart during late diastole?
Definition
ventricles are almost full (~150 mL)
Term
what is blood volume like in the heart during atrial systole?
Definition
ventricular volume increases slightly due to "topping off" from atrium. this is not highly critical, except if pts with atrial fibrillation are trying to run a race or something
Term
what is blood volume like in the heart during isometric contraction right after atrial systole?
Definition
this is the beginning of systole, where there is no change in volume b/c both the aortic and mitral valve are closed (lub is the sound of them closing)
Term
what is blood volume like in the heart during the ejection phase?
Definition
ventricular volume declines rapidly when the aortic valve opens
Term
what is blood volume like in the heart during the reduced ejection phase?
Definition
the ventricle begins to relax (due to repolarization of myocytes) when pressure in the aorta < ventricular pressure, so the aortic valve closes, and the mitral valve is still closed (dup sound is aortic backflow hitting the semilunar valves as they slam shut) - and there is another period of isovolumetric relaxation
Term
what is blood volume like in the heart during the rapid filling phase?
Definition
the pressure in the ventricle is less than atrial pressure, and blood flows from the atrium to the ventricle - the beginning of diastole
Term
what is end diastolic volume usually?
Definition
140 mL
Term
what is stroke volume usually?
Definition
75 mL
Term
what is residual volume usually?
Definition
65 mL
Term
what is the basic pattern in the wigger diagram?
Definition
electrical signal, contraction, and pressure change
Term
what is happening in terms of the aortic valve and pressure in diastole?
Definition
the aortic valve is close and aortic pressure is dropping
Term
what causes the mitral valve to open in late diastole? what happens when it opens?
Definition
the atrial pressure exceeds the intraventricular pressure by about 1 mm Hg. when the mitral valve opens, the ventricle fills
Term
what is the EKG P wave during late diastole?
Definition
depolarization of the atria, which "tops off" the ventricle (sound of this is the 4th heart sound)
Term
what is the "a wave" during diastole?
Definition
an increase in atrial pressure that occurs with atrial systole
Term
what happens at the beginning of systole in terms of valves? what is the pressure like?
Definition
the mitral and aortic valves are both closed, this is the period of isovolumetric contraction of the ventricle. at this point interventricular pressure is rising quickly
Term
what signals the end of diastole?
Definition
the R wave signals depolarization of the ventricle, after which tension begins to increase in the ventricular wall and the mitral valve closes -> first heart sound (beginning of systole)
Term
what marks the beginning of systole?
Definition
isovolumetric contraction, where the mitral and aortic valve remain close until the interventricular pressure exceeds aortic pressure and the aortic valve opens -> rapid ejection of blood.
Term
what is the "c wave"?
Definition
the increase in atrial pressure with isovolumetric contraction
Term
what does the T wave indicate during mechanical systole?
Definition
that the repolarization of the ventricles is complete
Term
at the end of systole, with the further relaxation of ventricle what happens?
Definition
the aortic valve closes, and initially blood moves backwards as recoil, creating a notch in the aortic pressure curve. vibration from this causes the 2nd heart sound - and the beginning of diastole
Term
when is the 3rd heart sound heard?
Definition
during rapid movement of the blood from the atria to the venticle (once intraventricular pressure drops below atrial and the mitral valve opens)
Term
what is the "x-descent"?
Definition
a decrease in atrial pressure during the rapid ejection phase of systole, and it's lowest point correlates with the peak ejection of blood from the aorta
Term
what is the v wave?
Definition
the increase in atrial pressure as the atria fill with blood
Term
what is the y descent?
Definition
the decrease in atrial pressure as the blood moves from the atria to the ventricles
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