Term
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Definition
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Term
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Definition
Ca Channel Blocker
↓ Inotropic (contraction)
↑Coronary dilation
Vasodilation (arteries)
- ↓ Afterload |
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Term
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Definition
Ca Channel Blocker
↓Chronotropic (HR) ↑Coronary dilation |
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Term
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Definition
Ca Channel Blocker
↓Chronotropic (HR) ↑Coronary dilation |
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Term
| Glyceryl trinitrate (Nitroglycerin) |
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Definition
Nitrovasodilators
Turns to NO -> turns GTP to cGMP -> dephosphorylates Myosin -> prevents myosin from contracting |
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Term
| Isosorbide dinitrate (Isordil, Sorbitrate) |
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Definition
Nitrovasodilators
Turns to ISMO -> turns to NO -> turns GTP to cGMP -> dephosphorylates Myosin -> prevents myosin from contracting |
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Term
| Isosorbide Mononitrate (ISMO) |
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Definition
Nitrovasodilators
Turns to NO -> turns GTP to cGMP -> dephosphorylates Myosin -> prevents myosin from contracting |
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Term
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Definition
Beta blocker
Nonselective, blocks β1 & β2 adrenic stimulation
↓Contraction
↓Heart rate
↓Conduction
↓Relaxation rate
↓Oxygen Demand |
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Term
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Definition
Beta blocker
Nonselective, blocks β1 & β2 adrenic stimulation
↓Contraction
↓Heart rate
↓Conduction
↓Relaxation rate
↓Oxygen Demand |
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Term
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Definition
Beta blocker
Nonselective, blocks β1 & β2 adrenic stimulation
- Reduces intraocular pressure
- Reduces blood pressure |
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Term
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Definition
Beta blocker
Nonselective, blocks β1 & β2 adrenic stimulation
- Reduces intraocular pressure
- Reduces blood pressure |
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Term
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Definition
Beta blocker
β1 selective antagonist w/intrinsic symp activity |
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Term
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Definition
Beta blocker
β1 selective
↓ HR & Cardiac Output ↓Renin release |
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Term
| Metoprolol (Lopressor, Toprol XL) |
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Definition
Beta blocker
β1 selective
↓ HR & Cardiac Output ↓Renin release |
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Term
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Definition
Beta blocker
β & α antagnoists (some β 2 agonism) |
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Term
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Definition
Beta blocker
β & α antagnoists (some β 2 agonism) |
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Term
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Definition
Antihypertensive
α1 antagonist, Dilates both arteries & veins |
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Term
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Definition
Antihypertensive
α1 antagonist, Dilates both arteries & veins |
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Term
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Definition
Antihypertensive
α1 antagonist, Dilates both arteries & veins |
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Term
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Definition
Antihypertensive
α1 antagonist, Dilates both arteries & veins |
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Term
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Definition
Antihypertensive
α1 antagonist, Dilates both arteries & veins |
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Term
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Definition
Antihypertensive
α2 agonist (brain), decreases release of NE & SNS tone, ↑Vasodilate |
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Term
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Definition
Antihypertensive
Relaxes arterioles directly, ↓BP, ↑Cardiac Output, ↓renal blood flow |
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Term
| Epinephrine (Adrenalin chloride) |
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Definition
Vesopressor
Non-selective direct acting adrenergic agonist
↑Contraction
↑HR
↑Cardiac Output
↑Vasoconstriction
- Bronchospasm (asthma, anaphylactic shock)
- Hypotension (anaphylactic shock)
- Increase anesthetics duration or action |
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Term
| Norepinephrine (Levophed) |
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Definition
Vesopressor
Non-selective direct acting adrenergic agonist
↑Vasoconstriction
↑BP
Treatment of Shock |
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Term
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Definition
Vesopressor
Non-selective direct acting adrenergic agonist
↑↑HR
↑↑ Contraction
↑Cardiac Output
Brochodilation (β2)
Asthma, cardiac arrest |
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Term
| Phenylephrine (Neosynephrine) |
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Definition
Vesopressor
Selective direct acting adrenergic agonist
Vasoconstriction
↑BP (reflex ↓HR)
Nasal decongestant |
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Term
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Definition
Vesopressor
Facilitates release & blocks reuptake of NE
NE effects; central stimulant action
ADHD |
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Term
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Definition
Vesopressor
Stimulates release of NE (indirect)
AND Directly stimulate β2 & α1 β1
NE effects
mild asthma |
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