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Cardio 16 - Artery and Venous Dz
Cardio
53
Medical
Professional
11/12/2012

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Term
Predisposing factors to peripheral arterial disease
Definition
***Smoking
-Hyperlipidemia, HTN
Coexisting CAD w/
-CHF
-Hx of MI
and Diabetes
Term
What is peripheral arterial disease
Definition
occlusive atherosclerotic disease of lower extremities
Term
Sites of occlusion/stenosis in PAD
Definition
-superficial femoral artery
-popliteal artery
-aortoiliac occlusive disease
Term
Prognosis PAD
Definition
-Intermittent claudication = good prognosis
-rest pain or ischemic ulcers = worst prognosis
Term
Symptoms PAD
Definition
-Intermittent claudication
-Rest pain- often small arteries, at NIGHT, suggests severe ischemia
Term
Signs PAD
Definition
-Diminished or absent pulses, muscular atrophy, dec. hair, thick toenails, dec. temperature
-Ischemic ulcers - often on toes, localized necrosis, 2' to local trauma doesn't heal, can become infected/gangrenous
-Pallor elevated, rubor when dependent
Term
Dx PAD
Definition
1. Ankle-brachial index (ABI)
2. Pulse volume recording - assess limb perfusion
3. Arteriography *gold standard* dx PAD
Term
TX PAD-conservative
Definition
***Stop smoking
-Exercise program
-Foot care, especially diabetics
-reduce atherosclerotic risk factors- Hyperlipidemia, HTN, diabetes, weight
-Avoid extreme temps
-Aspirin w/ clopidogrel slight symptom improvement
Term
Tx PAD- surgical
Definition
-Indicated w/ rest pain, ischemic ulcers, severe symptoms
1. Angioplasty w or w/o stent
2. Bypass grafting
Term
ABI in PAD
Definition
ratio systolic BP at ankle to arm
-Normal 0.9-1.3
>1.3 non-compresible vessels = severe dz
< 0.7 claudication
<0.4 rest pain
Term
Cause Acute limb Ischemia
Definition
1. Thrombus
2. Embolus
-trauma, compression, hematoma
Term
6 Cardinal signs of Acute limb ischemia
Definition
The 6 P's
1. Pain
2. Pallor
3. Polar (cold)
4. Paralysis
5. Paresthesia
6. Pulselessness
Term
Dx Acute Limb ischemia
Definition
1. Arteriogram - site of occlusion
2. ECG - look for MI, Afib
3. Echo - check valves, clots, MI
Term
Tx A limb ischemia
Definition
**Assess ability to save limb viability of tissue
1. IV Heparin
2. Sx embolectomy, balloon, bypass if fail
3. Thrombolytics - mixed results
Term
What is an aortic aneurysm
Definition
localized dilation of aorta
-1.5Xs normal size
Term
Risk factors Aortic Aneurysm
Definition
Age
Men >women
trauma
HTN
vasculitis
smoking
family Hx
Syphilis
Connective tissue disorders (Marfan's)
Term
What causes AAs
Definition
Multifactorial
- atherosclerotic weakening of wall
-All three layers expand
-destruction of collagen and elastin from inflammation and wall stress
Term
Two types of AAs
Definition
1. Saccular- out-pouching of segment of vessel
2. Fusiform - circumferential expansion entire vessel
Term
Presentation of AAs
Definition
-Usually asymptomatic
-Sense of "fullness
-May have pain
Term
Physical Exam of AA
Definition
-Pulsatile mass on exam
-Sudden severe pain radiates, ecchymosis = impending rupture
Term
Signs of Abdominal Aortic Aneurysm
Definition
Triad:
-Abdominal pain
- Hypotension
-palpable pulsatile abdominal mass
Also see syncope, N/V
Term
Tx AAA if ruptured
Definition
Emergent Laparotomy
Term
Dx AA
Definition
-U/S best, see size and location
- CT- good but slower, good pre-op planning
-Radiograph - occasionally seen, not routinely used
Term
Tx Aortic Aneurysm-unruptured
Definition
Depends on size
>5cm or symptomatic - Sx resection w/ graft
<5cm or asymptomatic - controversial, monitor
Term
Tx ruptured AA
Definition
Emergent Sx repair
-open repair usually, some may be done endovascularly
Term
Predisposing Factors Aortic Dissection
Definition
-Longstanding HTN
-Cocaine use
-Trauma
-Connective Tissue diseases
-Bicuspid aortic valve
-Coarctation of aorta
-3rd trimester pregnancy
Term
Classification of Aortic Dissection
Definition
Type A (proximal) - ascending aorta

Type B(distal) - descending aorta
Term
Presentation of Aortic Dissection
Definition
-Severe pain, ripping/tearing/stabbing
Type A-anterior chest pain
Type B- Interscapular chest pain
-Diaphoresis
-Usually Hypertensive, some Hypo
-asymmetrical BP and pulses
-Aortic regurge
-Neuro symptoms
Term
How Tx Aortic Dissection-medically
Definition
IMMEDIATELY
-IV B-blocker
-IV sodium nitroprusside
Term
Tx Aortic Dissection Type A
Definition
-Most Sx emergency
Term
Tx Aortic Dissection Type B
Definition
-Medical management
-Lower BP, B-blockers
-pain control
-if symptoms persist, may req. Sx
Term
What genetic defects can lead to aortic dissection
Definition
Connective Tissue Diseases
-Marfan's Syndrome
-Ehlers-Danlos Syndrome
Term
Pathology of Varicose Veins
Definition
valves do not function properly
blood to stay in the vein
pools causes the vein to swell
Term
What are Varicose Veins
Definition
- swollen, twisted, and sometimes painful veins that have filled with an abnormal collection of blood.
Term
Causes of Varicose Veins
Definition
-Pregnancy
-Thrombophlebitis
-Birth defect valves
Term
Symptoms of Varicose veins
Definition
-Fullness, heaviness, aching, and sometimes pain in the legs
-Visible, swollen veins
-Mild swelling of ankles
-Brown color of the skin at the ankles (in more severe cases)
-Skin ulcers near the ankle (in more severe cases)
Term
Tx Varicose Veins-general
Definition
-Avoid standing for too long
-Raise your legs when resting or sleeping
-Wear elastic support hose
Term
Tx Varicose Veins - Sx indicated
Definition
-If pain / heaviness of legs
-skin ulcers
-cosmetic concern
-thickening of skin
Term
How Sx tx Varicose Veins
Definition
Laser ablation
Radiofrequency ablation
Sclerotherapy (which is often done to improve appearance)
Term
Presentation Superficial Phlebitis
Definition
*Virchow's Triad
-Usually IV site UE
-Varicose vein LE
Term
S&S Superficial Phlebitis
Definition
-Pain, tenderness, induration, erythema along vein
-Tender cord may be palpable
Term
Tx Superficial Phlebitis-localized thrombophlebitis
Definition
mild analgesic
continue activity
Term
Tx Superficial Phlebitis - severe
Definition
-Bed rest, elevation, hot compress
-When symptoms resolve - ambulation w/ compression hose
-If suppurative, Abx, drain ??
-Septic Phlebitis can be due to infected IV cannula, remove and systemic Abx
Term
Chronic Venous Insufficiency
Definition
-can be superficial, deep or both
-Often Hx DVT
Term
Causes of CVI
Definition
-Destruction of venous valves from DVT or chronically elevated pressure
-leads to incompetence against gravity
Term
Progression of CVI
Definition
-Leads to ambulatory venous HTN = edema and brawny discoloration
-reduced capillary flow and hypoxia of tissues
-Mild trauma can = tissue death
-Venous ulcers
Term
Presentation of CVI
Definition
-Swollen LE- worse at end of day or prolonged sitting/standing
-elevation of legs provides relief
-Skin thin, atrophic, shiny, cyanotic
-Brawny induration
-Venous Ulcers- often Medial malleolus
Term
Chronic Venous Insufficiency
Definition
-can be superficial, deep or both
-Often Hx DVT
Term
Causes of CVI
Definition
-Destruction of venous valves from DVT or chronically elevated pressure
-leads to incompetence against gravity
Term
Progression of CVI
Definition
-Leads to ambulatory venous HTN = edema and brawny discoloration
-reduced capillary flow and hypoxia of tissues
-Mild trauma can = tissue death
-Venous ulcers
Term
Presentation of CVI
Definition
-Swollen LE- worse at end of day or prolonged sitting/standing
-elevation of legs provides relief
-Skin thin, atrophic, shiny, cyanotic
-Brawny induration
-Venous Ulcers- often Medial malleolus
Term
Tx CVI before Ulcers
Definition
-Leg elevation throughout day and night above heart
-avoid prolonged sitting/standing
-Can do Sx
-Diuretics
Term
Tx CVI w/ venous ulcers
Definition
-Wet to Dry saline dressings
-Compression Hose, Unna boot
-Split-thickness skin graft may be needed
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