Term
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Definition
| Oral Administration, Prevents recirculation of bile acids, results in increasing metabolism of cholesterol, not used in patients with elevated triglycerides |
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Term
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Definition
| Powder must be mixed, taken with meals, tablets swallowed whole, bad taste, not to be used with amiodarone |
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Term
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Definition
| Produces a decrease in LDL and triglyceride, produces increase in HDL, use with caution in diabetics, assess liver function, baseline uric acid and blood glucose, administer with Tylenol or ASA to minimize adverse effects, hepatotoxicity & myopathy are serious side effects |
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Term
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Definition
| Reduce LDL, Increase HDL, Administer at night w/ evening meal, Reduces factors that contribute to heart attacks (vasodilation, decrease plaque and thromboembolism) Monitor liver function tests, assess for myopathy, rhabomyolysis, avoid grape juice |
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Term
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Definition
| Lower Triglyceride levels, Raise HDL, the most effective triglyceride lowering agent, must be used in caution with statins, assess for gallbladder dz and hepatotoxicity, assess for myopathy, monitor for hypoglycemia, 1 hr before or 4 hr after bile resins |
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Term
| Zetia (Cholesterol Absorption Inhibitor) |
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Definition
| Reduce arthrosclerosis, Reduced total cholesterol, LDL and triglycerides: Inhibits absorption of cholesterol from food, may be used with statins, assess for hepatitis and myopathy, contraindicated in renal dysfunction, not recommended with fibric acid, administer 1 hour before or 4 hours after administration of bile acid resins |
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Term
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Definition
| Reduce artherosclerosis, reduces triglyceride levels, may be used with statins, Use in caution with patient allergic to fish, limited adverse effects |
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Term
| Drugs to treat hypertension |
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Definition
| Preferred: Diuretics, Beta Blockers; Alternative: Ace inhibitors, ARBs, calcium channel blockers, alpha-1 adrenergic blockers; Adjunctive agents: alpha-2 agonists, adrenergic antagonists, direct vasodilators |
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Term
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Definition
| "Lols", Inhibit cardiac response to sympathetic nerve stimulation, minimal hypotension, effect on sexual function, slowing of CNS, not as effective on African Amercans, use with thiazide diuretics, Do not use in asthma, type 1 diabetes, heart failure and peripgheral vascular dz, AV block, sinus bradycardia, Avoid sudden discontinuation |
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Term
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Definition
| Decrease BP, Preserve CO, increase renal blood flow, more effective with diuretic therapy, common adverse effect of chronic cough, serious sede effects of angiodema, 1st dose hypotension, drug interactions with antacids, potassium supplements |
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Term
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Definition
| Block Angiotensen II efects, lowers BP, stroke prevention, progressin of diabetic nephropathy, african americans do not respond well, serious side effects of potential for birth defects, drug interactions of cimetidine and fluconazole |
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Term
| Aldosterone receptor antagonist: Inspra |
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Definition
| Prevents sodium reabsorption, use to treat HTN and heart failure, note contraindications, serious side effects of hyperkalemia, increases in lipid levels |
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Term
| Calcium Channel Blockers "pines" |
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Definition
| Peripheral vasodilating effects, reduces afterload, acts on arterioles, veins are not affected, more effective with higher pretreatment BP, effective in African Americans, take BP every shift, monitor for bradycardia, perform daily weights, may increase levels of digoxin, avoid grape juice |
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Term
| Alpha-1 Adrenergic Blocking Agents |
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Definition
| No incarease in heart rate and no effect on uric acide concentrations, use in males with benign prostatic hyperplasia |
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Term
| Centrally Acting Alpha-2 Agonists |
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Definition
| Acts with in the CNS to decrease the sympathetic outflow, results in vasodilation, bradycardia, decrease CO, used only in combination, more frequent adverse effects, methyldopa often causes fluid retention, assess for depression and affect, clonidine patch may develop contact dermatitis, tolerance to alcohol may be diminisehd |
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Term
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Definition
| Hydralazine: May cause an increase in heart rate, CO, serious adverse effects of immunologic inflammatory |
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Term
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Definition
| Minoxidil: Used in severe hypertensive patients, also used as a hair growth stimulant |
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Term
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Definition
| Nitroprusside sodium: Use with sudden sever hypertensive crisis, solution may be light brown in color |
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Term
| Drugs to treat dysrhythmias |
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Definition
| Alter cardiac electrophysiologic function to treat or prevent dysrhthmias; Na Channel Blcokers, Beta Adrenergic blockers, potassium channel blockers, calcium channel blockers |
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Term
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Definition
| 1a: Procainamide, 1b:lidocaine, 1c:propafenone (Rythmol); SVT, VT, A-flutter, A-Fib, Serious side effects of systemic lupus, toxicity (monitor therapeutic level), hypotension |
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Term
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Definition
| Propranolol; Ventricular dysrhthmias, monitor for CNS effects, respiratory arrest, dilantin for seizures |
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Term
| Potassium Channel Blockers |
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Definition
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Term
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Definition
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Term
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Definition
| Propranolol, Severe Vtach, Brady cardia, monitor for chest pain, edema |
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Term
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Definition
| A fib, aflutter, paroxysmal SVT, htn, angina, monitor for hypotension, bradycardia, heart failure, check apical pulse before administration |
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