Shared Flashcard Set

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Carbohydrate Metabolism/ Dietary Carbohydrate Strategies
Sports nutrition
50
Nutrition
Undergraduate 1
10/11/2015

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Cards

Term
Are carbohydrates the only macronutrient to be oxidized both Anaerobically and Aerobically?(Yes or No)
Definition
Yes
Term
In addition to fueling skeletal muscle, carbs also serve as fuel for __ and __.
Definition
CNS(brain and spinal cord) and red blood cells.
Term
What happens if one doesn't ingest any carbohydrates?
Definition
The body will turn fats and protein into glucose by a process called gluconeogenesis.
Term
Which three sugars make up Monosaccharides?
Definition
Glucose, Fructose, and Galatose
Term
Which three sugars make up disaccharides?
Definition
Sucrose, lactose, and maltose
Term
What's another name for glucose?
Definition
Dextrose
Term
Fructose
Definition
Fruit Sugar. The small intestine absorbs fructose directly into the blood and the liver slowly converts it to glucose.
Term
Galactose
Definition
Converted to glucose in the liver and is either stored as liver glycogen or released into the blood.
Term
Sucrose
Definition
Most common disaccharide, consist of glucose and fructose.
Term
Lactose
Definition
Found in milk. Comprised of glucose and galatose
Term
Maltose
Definition
Contains two glucose molecules
Term
Oligosaccharides
Definition
Carbohydrates composed of short chains of 3 to 9 linked sugars. Found in many vegetables
Term
Polysaccharides
Definition
Contain 10 to 1000s of monosaccharides. Starch and fiber represent two forms of plant polysaccharides
Term
What are the two forms of Starch?
Definition
Amylopectin(rapidly digested)
and amylose(slowly digested)
Term
True or false.
Glucose is the final common pathway for transport of almost all carbohydrates to the tissue cells.
Definition
True
Term
GLUT-4
Definition
Protein carrier molecule that transports glucose into the sarcoplasm
Term
What stimulates the migration of GLUT-4?
Definition
Insulin and physical activity
Term
What are the normal levels of blood glucose ranging from?
Definition
70-110mg/dl
Term
What happens if blood glucose levels are elevated?
Definition
Pancreas will secrete insulin to reduce blood glucose levels
Term
What happens if blood glucose levels are low?
Definition
Liver glycogen is broken down and gluconeogenesis increases blood glucose levels.
Term
The phosphorylation of glucose is almost entirely irreversible except in the __ cells.
Definition
Liver
Term
Glycogen
Definition
Storage form of carbohydrates in the liver and skeletal muscles.
Term
How many grams of water does a gram of glycogen store?
Definition
3
Term
How many kilo calories does a typical male store?
Definition
2000 kilocalories
Term
Name the four steps of glycogen synthesis
Definition
1)glucose to glucose-6-phosphate via hexokinase
2)glucose-6-phosphate to glucose 1-phosphate via phoshoglucomutase
3)Glucose 1-phosphate to UDP glucose via UDP glucose pyrophosphorylase. UDP then breaks off
4)Glucose to glycogen via glycogen synthase
Term
Name the three step process of glycogen breakdown
Definition
1) Glycogen to glucose 1-phosphate via glycogen phosphorylase
2) Glucose 1-phosphate to glucose-6 phosphate via phosphoglucomutuase
3)Glucose-6-phosphate goes to glycolysis
Term
What is glycolysis?
Definition
Breakdown of glucose to form pyruvate
Term
After an overnight fast, to what extent are glycogen levels depleted, if at all?
Definition
70-80%
Term
Continued release of anaerobic energy in glycolysis depends on NAD+ availability. What happens if NAD+ is depleted?
Definition
glycolysis will shut down
Term
What happens if NADH gets "backed up"?
Definition
This happens when exercise intensity is too high for too long.
Term
What is the enzyme that catalyzes Pyruvate with lactate?
Definition
lactate dehydrogenase
Term
What happens to lactate that is produced during high intensity exercise?
Definition
Used to make ATP
Term
Lactate usage in the body:
70-80% ___
20-30% ___
Definition
70-80% is oxidized and used as energy
20-30% is taken to the liver and converted into glucose(cori cycle)
Term
Physiologic values of lactate range from __1mmol/L at rest to over __mmol/L following maximal-intensity exercise lasting at least 30 seconds.
Definition
1 mmol/L at rest and over 20 mmol/L
Term
(True or False)
The best method to determine peak lactate levels is with a blood sample right after exercise.
Definition
False
The best method is to take serial measurements spaced maximally two minutes apart for about 10 minutes or until lactate concentrations decline.
Term
Carbohydrates oxidized during exercise can originate from which 5 potential sources?
Definition
1)muscle glycogen
2) liver glycogen
3) blood glucose'
4) carbs ingested during exercise( Gatorade)
5) gluconegenic sources
Term
Crossover Concept
Definition
Carbohydrates and fats are oxidized as a mixture, and whether carbohydrates or fat is predominant fuel depends on several factors, the most important being exercise intensity and duration.
Term
Glycogenolysis
Definition
Breakdown of glucose from glycogen
Term
What does Glucogon do?
Definition
Increases blood glucose
Term
A major drop in blood glucose only occurs under what circumstances?
Definition
When exercise is prolonged for several hours.
Term
What explains a rise in blood glucose during high intensity exercise(assuming no ingestion of carbohydrate)?
Definition
Hepatic glucose output exceeds the skeletal muscle glucose uptake.
Term
General recommendations for athletes in regards to daily carbohydrates intakes are:
Definition
6 to 10 grams of carbohydrates per kilogram body weight per day (grams/kg/day)
Term
Train low, Compete High
Definition
Low carb days followed by several days of high carbs prior to a event. It doesn't improve exercise performance in endurance athletes.
Term
Carbohydrate Loading
Definition
Classical Loading: 3 days of low carbs followed by 3 high carb days(90% of calories)

Modified Carb Loading: 3 days moderate carbs(50% total calories) then 3 days of high carbs (70% total calories).

1-Day loading: High carb day (10 grams/kg/day) followed with a day of rest.
Term
Rebound Hypoglycemia
Definition
During the beginning of exercise, when insulin and blood glucose levels both decrease, with blood glucose levels decreasing to levels below baseline and reaching hypoglycemic levels.
Term
Does pre and during exercise galactose improve endurance performance? (yes or no)
Definition
No. There's scientific research that proves it.
Term
__>__>__
Glucose, galactose/fructose, placebo
Definition
glucose> galactose/fructose> placebo
Term
SGLT1
Definition
Transporter that takes glucose from inside the intestines and delivers it to the blood vessels.
Term
GLUT5
Definition
Transporter for fructose
Term
Fructose is better for resynthesizing liver glycogen or muscle glycogen?
Definition
liver glycogen
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