Term
|
Definition
|
|
Term
|
Definition
Surgery
THEN
Chemotherapy and Radiation
Chemo = carboplatin + paclitaxel |
|
|
Term
NSCLC
Stage IIIa treatment |
|
Definition
Chemotherapy and XRT
THEN
Surgery
Chemo = carboplatin + paclitaxel |
|
|
Term
NSCLC
Stage IIIb treatment
|
|
Definition
Chemotherapy + Radiation
(surgery not possible)
|
|
|
Term
|
Definition
Only treat good performance status
Chemo + Bevacisumab
No radiation or surgery
Bevacisumab only if non squamous
Chemo = Carboplatin + paclitaxel |
|
|
Term
NSCLC
Relapse Treatment (1st relapse) |
|
Definition
Single Agent Chemo + Bevacisumab
only give Bev if havent received it before |
|
|
Term
NSCLC
Multiple Relapse Treatment |
|
Definition
|
|
Term
SCLC
Limited Stage Definition |
|
Definition
Only in one lung and nearest lymph nodes
(only one radiation area) |
|
|
Term
SCLC
Extensive Stage definition |
|
Definition
Both lungs or outside lungs and thoracic cavity
distant mets |
|
|
Term
SCLC
Limited Stage Treatment |
|
Definition
NO surgery
Chemo + radiation concurrently + Prophylactic CI
Prophylactic CI only if complete response
Chemo = cisplatin and etoposide |
|
|
Term
SCLC
Extensive Stage treatment |
|
Definition
NO surgery
Chemo Only!
Chemo = cisplatin and etoposide
radiation is palliation only |
|
|
Term
Pancreatic Cancer
Name the 3 stages |
|
Definition
Resectable Tumors
Unresectable Locally Advanced Tumors
Unresctable Metastatic Tumors |
|
|
Term
Pancreatic Cancer
Resectable Tumor Treatment |
|
Definition
Sugery: Whipple Procedure
Chemotherapy:
Gemcitabine (single agent)
or
5FU/Leucovorin
|
|
|
Term
Pancreatic Cancer
Unresectable Locally Advanced Tumor Treatment
with Good Performance Status |
|
Definition
FOLFIRINOX
OR
GEMCITABINE COMBINATIONS
(ERLOTINIB, CAPECITABINE, DOCETAXEL) |
|
|
Term
Pancreatic Cancer
Unresectable Locally Advanced Tumors
(Poor Performance Status) |
|
Definition
|
|
Term
Pancreatic Cancer
Unresectable Metastatic Tumor
(Good Performance Status) |
|
Definition
FOLFIRINOX
OR
Gemcitabine combinations
(erlotinib, capecitabine,docetaxel) |
|
|
Term
Pancreatic Cancer
Unresectable Metastatic Tumor
(poor performance status) |
|
Definition
|
|
Term
Pancreatic Cancer
Resectable disease
goal of therapy |
|
Definition
|
|
Term
Pancreatic Cancer
nonresectable regional disease
goal of therapy |
|
Definition
| Prolong life and palliation of symptoms |
|
|
Term
Pancreatic Cancer
unresectable disease with distant mets (stage IV)
goals of therapy |
|
Definition
|
|
Term
| Risk factors of Pancreatic Cancer |
|
Definition
older age (>50)
smoking
pancreatitis
alcoholism
occupational exposure to DDT or petroleum
diabetes
high fat diet
obesity
inactivity |
|
|
Term
Ovarian Cancer
Risk Factors |
|
Definition
Family History
Nulliparity
1st child after 35yo
Advanced Age
American and European Descent
prolonged use of ovulation drugs |
|
|
Term
Ovarian Cancer
Initial Treatment |
|
Definition
Surgery!
Everyone gets it!
debulks tumor to less than 2cm
Most all patients get chemo
Stage II-IV
Intraperitoneal
Paclitaxel + Cisplatin
IV
Paclitaxel + Carboplatin
|
|
|
Term
Ovarian Cancer
Relapse Treatment
(goal and therapy) |
|
Definition
goal is palliation
platinum senstive (>6months) - repeat initial treatment
Platinum resistant (<6 months) - single therapy chemo
topotecan
liposomoal doxorubicin
etoposide
gemcitabine
altretamine
Blue most common
|
|
|
