Term
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Definition
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Term
|
Definition
| Surgery, 5FU + Leucovorin |
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Term
|
Definition
| Surgery, FOLFOX (5FU, Leucovorin, Oxaliplatin) |
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Term
|
Definition
FOLFOX (5FU, Leucovorin, Oxaliplatin) or FOLFIRI (5FU, Leucovorin, Irinotecan) + Bevacizumab, Palliative surgery
NOT CURATIVE |
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Term
| Colon cancer recurrence (Salvage therapy) |
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Definition
Good performance = Combo tx
Poor performance = single tx
Possible drug regimens inclue: FOLFOX/FOLFIRI + Bevacizumab, Oxaliplatin, Capecitabine, Irinotecan, Cetuximab.
Note: You CAN use 5FU for salvage tx in colon cancer. |
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Term
|
Definition
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Term
|
Definition
| Surgery, XRT w/ 5FU, Chemo: 5FU + Leucovorin |
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Term
|
Definition
| Neoadjuvant XRT + 5FU, Surgery, FOLFOX |
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Term
|
Definition
FOLFOX/FOLFIRI + Bevacizumab
NOT CURATIVE |
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Term
|
Definition
Surgery, radiation (if necessary), chemo
Chemo: Doxurubicin + Cyclophosphamide (AC), trastuzumab (if HER2+), tamoxifen x 5 years if ER/PR+ and premenopausal, aromatase inhibitor if ER/PR+ and postmenopausal |
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Term
|
Definition
Surgery, radiation (if necessary), chemo
Chemo: Doxurubicin + Cyclophosphamide (AC), trastuzumab (if HER2+), tamoxifen x 5 years if ER/PR+ and premenopausal, aromatase inhibitor if ER/PR+ and postmenopausal |
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Term
|
Definition
Neoadjuvant chemo, surgery, radiation (if necessary), chemo
Chemo: Doxurubicin + Cyclophosphamide (AC), trastuzumab (if HER2+), tamoxifen x 5 years if ER/PR+ and premenopausal, aromatase inhibitor if ER/PR+ and postmenopausal |
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Term
|
Definition
Radiation (if necessary), chemo
Chemo: Doxurubicin + Cyclophosphamide (AC), trastuzumab (if HER2+), tamoxifen indefinitely if ER/PR+ and premenopausal, aromatase inhibitor indefinitely if ER/PR+ and postmenopausal |
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Term
| Breast cancer salvage therapy |
|
Definition
use different chemo than the first regimen (anthracycline or taxane preferred)
Drugs to try: capecitabine, lapatanib (HER2+), paclitaxel, ixabepilone |
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Term
|
Definition
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Term
|
Definition
| Surgery, Carboplatin + paclitaxel, radiation |
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Term
|
Definition
| Neoadjuvant chemo, neoadjuvant radiation, surgery |
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Term
|
Definition
| Carboplatin + paclitaxel, radiation |
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Term
|
Definition
Good performance = Carboplatin + paclitaxel + bevacizumab
Poor performance = Do not treat or palliative surgery/radiation |
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Term
|
Definition
Poor performance = Do not treat
Good performance:
-1st Relapse = Single agent chemo (different than what was first used) + bevacizumab
-2nd relapse = erlotinib |
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Term
|
Definition
Grades 1 & 2: Surgery + observation
Grade 3: Surgery + IV carboplatin + IV paclitaxel |
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Term
|
Definition
| Surgery + IV Carboplatin + IV Paclitaxel |
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Term
|
Definition
Surgery + Intraperitoneal CISplatin + IP Paclitaxel
Note: Intraperitoneal chemo only studied in stage III |
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Term
|
Definition
| Surgery + IV Carboplatin + IV Paclitaxel |
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Term
| Ovarian cancer salvage therapy |
|
Definition
Platinum sensitive (relapse > 6 mo after Pt tx) = Repeat initial chemo
Platinum resistant (Relapse < 6 mo) = Non-Pt chemo (liposomal doxorubicin, topotecan, gemcitabine) |
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Term
| Limited small cell lung cancer |
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Definition
CISplatin + Etoposide + XRT
Pt's w/ complete remission should have prophylactic cranial XRT |
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Term
| Extensive small cell lung cancer |
|
Definition
| CISplatin + etoposide + palliative radiation/surgery |
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Term
| Small cell lung cancer relapse |
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Definition
Single-agent chemotherapy:
-Topotecan, irinotecan, docetaxel, paclitaxel, vinorelbine, carboplatin |
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Term
| Pancreatic cancer w/ resectable tumors |
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Definition
| Surgery + radiation + 5FU |
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Term
| Non-resectable LOCAL tumor pancreatic cancer |
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Definition
Radiation + 5FU
Gemcitabine +/- erlotinib |
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Term
| Non-resectable METASTATIC tumor pancreatic cancer |
|
Definition
| Gemcitabine +/- erlotinib |
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