Term
| Cell Cycle Specific Drugs |
|
Definition
| M - Mitotic Inhibitors, A - Antimetabolites, T - Topoisomerase Inhib. |
|
|
Term
| made from Vinca alkaloids and mandrake plants |
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
| prevents mitosis, cell division and cause cell death |
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
| Mitotic Inhibitors - what phase? |
|
Definition
|
|
Term
| S/E - all usual + liver/kidney |
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
|
Definition
| Mitotic Inhibitors, Specific |
|
|
Term
|
Definition
|
|
Term
|
Definition
| neurotoxicity - tingling, numbness in fingers and toes |
|
|
Term
| high chance of hypersensitivity - give steroid, antihistamine 1st |
|
Definition
|
|
Term
| Halt synthesis of cell protein |
|
Definition
| Antimetabolites, Specific |
|
|
Term
| Antimetabolites work in what phase? |
|
Definition
|
|
Term
| Like an artificial building block |
|
Definition
| Antimetabolites, Specific |
|
|
Term
| Antimetabolites, Specific - used for |
|
Definition
| Colon/rectum. breast, lung |
|
|
Term
|
Definition
| Antimetabolites, Specific |
|
|
Term
|
Definition
|
|
Term
| Also used for Tx of rheumatoid arthritis & psoriasis |
|
Definition
|
|
Term
|
Definition
|
|
Term
| may cause photsensitivity, skin & GI toxicity |
|
Definition
|
|
Term
|
Definition
| Antimetabolites, Specific |
|
|
Term
|
Definition
| Antimetabolites, Specific |
|
|
Term
| Do not interrupt infusion |
|
Definition
|
|
Term
| S/E - hyperuricemia, hepatotxicity |
|
Definition
|
|
Term
|
Definition
|
|
Term
| S/E - cerebellar dysfunction (balance, gait) |
|
Definition
|
|
Term
|
Definition
| Alkalating Agent, non-specific |
|
|
Term
|
Definition
| Alkalating Agent, non-specific |
|
|
Term
|
Definition
|
|
Term
| nitrogen mustard derivative |
|
Definition
|
|
Term
| empty bladder, encourage 2-3L fluid |
|
Definition
|
|
Term
| nephrotoxic, neurotoxic, ototoxic |
|
Definition
|
|
Term
| May give Ethyol to reduce risk of neurotexicity |
|
Definition
|
|
Term
| used for bladder, testical and ovarian solid tumors |
|
Definition
|
|
Term
|
Definition
| Antitumor Antibiotic, non-specific |
|
|
Term
|
Definition
| Antitumor Antibiotic, non-specific |
|
|
Term
|
Definition
| Antitumor Antibiotic, non-specific |
|
|
Term
|
Definition
| Antitumor Antibiotic, non-specific |
|
|
Term
|
Definition
|
|
Term
| Must have healthy heart to use |
|
Definition
|
|
Term
|
Definition
|
|
Term
| May give w/Zinegard to protect heart |
|
Definition
|
|
Term
| May cause pulmonary toxicity |
|
Definition
|
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