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Cancer drug MOA
Therapeutics (VI) exam 1
20
Other
Not Applicable
03/17/2013
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Term

Gemcitabine

  • Class
  • MOA
  • Specific?
 Definition
  • Cytidine analogs 
  • Inhibit DNA polymerase/ False metabolite
  • Yes
Term

Fludarabine

  • Class
  • MOA
  • Specific?

 

 Definition
  • Purine analogue
  • Fasle metabolite
  • Yes
Term

5-fu

  • Class
  • MOA
  • Specific?
 Definition
  • Pyrimidine analog
  • False metabolite
  • Yes
Term
Vincristine
 Definition
  • Vinca
  • Mitotic inhibitor, binds tubulin
  • Yes
Term

Paclitaxel

  • MOA
  • Specfic?
 Definition
  • Binds tubulin/ inhibit disassembly 
  • Yes
Term

Ixabipalone

  • Class
  • Moa
 Definition
  • Epothilone
  • Binds Microtubule
Term

Eribulun

  • MOA
 Definition
  • Binds Microtubule
Term

Etoposide

  • Class
  • MOA
  • specific?
 Definition
  • Epipodophyllotoxin
  • Topo 2
  • Yes
Term

Irinotecan

  • Class
  • MOA
  • specific?
 Definition
  • Camptothecan
  • Topo 1
  • No
Term

Doxorubicin

  • Class
  • MOA
  • Specific?
 Definition
  • Anthracycline
  • Topo 2
  • No
Term

Mitoxantrone

  • Class
  • MOA
  • Specific?
 Definition
  • Anthracycline
  • Topo 2
  • No
Term

Cyclophosphamide

  • Class
  • MOA
  • Specific?
 Definition
  • Nitrogen mustards
  • DNA
  • Yes
Term

Carboplatin

  • Class
  • MOA
  • Specific?
 Definition
  • Platinums
  • DNA
  • No
Term
Trastuzumab
 Definition
  • HER2
Term
Rituximab
 Definition
  • CD20
Term
Alemtuzumab
 Definition
  • CD52
Term
Cetuximab
 Definition
  • EGFR
Term
Panitumumab
 Definition
  • EGFR
Term
Bevacizumab
 Definition
  • VEGF
Term

Carmustine

  • Class
  • MOA
  • Specific?
 Definition
  • Nitrosourea
  • Alkylating agent
  • NO
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