Shared Flashcard Set

Details

Cancer Complications and treatment
Pathophysiology 2
13
Health Care
Graduate
09/22/2009

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Cards

Term
Bony Metastases
Definition
Cancer spreading to bone
Term
Bony Metastases Symptoms
Definition
Usually back pain, usually in thoracic or ribs. Feels worse after sleep
Term
Bony Metastases Red Flag
Definition
Night pain
Term
Bony Metastases Complications
Definition
Spinal cord compression, intractable pain, pathological fracture
Term
Spinal cord compression
Definition
Malignancies that spread to spinal cord. Can involve vertebral area.
Term
Malignancies with propensity to spread to bone
Definition
LU, breast, prostate
Term
Spinal cord compression initial symptoms
Definition
Back pain
Term
Spinal cord compression Treatment
Definition
Surgically debulk, radiation, chemo
Term
Chemotherapeutic agents: OLD
Definition
Kill dividing cells, hope to kill cancer more than normal since they divide more often.
Term
Chemotherapeutic agents: OLD types
Definition
Alkalyting agents: bind to, disrupt DNA
Folate antagonists: inhibits folate activity to decrease replication
Term
Chemotherapeutic agents: OLD: Side effects
Definition
Non selective. Suppress bone marrow, toxic to cerebellum, neuropathy, nausea, vomiting
Term
Chemotherapeutic agents: NEW
Definition
Biologic agents. Target metabolic pathways or receptors in cancer cells. More selective. More tolerable side effects.
Term
Chemotherapeutic agents: NEW:ex: breast cancer
Definition
Her2Neu receptor. Drug: Herceptin inhibits receptor to decrease the cancer.
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