Term
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Definition
| nonhereditary. do not exhibit obvious inherited pattern |
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Term
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Definition
| 2 members of each chromosomepair |
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Term
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Definition
| 2 alleles for given gene are identical |
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Term
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Definition
| in heterozygous genes- only one allele necessary for effect |
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Term
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Definition
| frequency with which given dominant/recessive allele yields expected trait in the population |
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Term
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Definition
| presence of 2 mutations is required to create certain cancer-retinoblastoma. |
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Term
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Definition
| the loss of gene opens door to excessive cell proliferation and cancer |
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Term
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Definition
| inherited mutation responsible for familial adenomatous polyposis. |
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Term
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Definition
| gene critical for the control of cell proliferation and survival in many cells |
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Term
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Definition
| preserve integrity of cell's genome. its loss doesn't directly affect cell proliferation |
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Term
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Definition
| sensitive to UV radiation. requires 2 mutant copies of same gene to be inherited. |
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Term
| hereditary nonpolyposis colon cancer |
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Definition
| not many polyps form in colon. caused by mismatch repair disrupted. dominant pattern. |
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Term
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Definition
| can cause breast cancer when mutated. moderate to high risk. repair DNA damage. usually hereditary. caretaker gene. |
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Term
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Definition
| ataxia telangiectasia mutated. recessive. codes for DNA damage response protein. |
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Term
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Definition
| short stature, sun-induced facial rashes, immunodeficiency. Lymphomas, leukemias, mouth cancer, stomach (to name a few). BLM gene- DNA helicase not coded for when gene mutated. |
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Term
| multipole endocrine neoplasia type II |
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Definition
| development of benign/malignant tumors of endocrine gland. RET gene. |
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Term
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Definition
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Term
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Definition
| lab tests that analyze a person's DNA for inherited mutations. |
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