Term
| Who is Dr. Barry Marshall? |
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Definition
| the guy who ingested H. pylori to induce a peptic ulcer (that he treated). his abstract was initially rejected. |
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Term
| what is the shape and stain of H. pylori? |
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Definition
| gram- rod (kinda pleomorphic) |
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Term
| where does H. pylori colonize? |
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Definition
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Term
| (likely test question) how does H. pylori colonize the stomach? |
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Definition
| it produces Urease which promotes the formation of ammonia that neutralizes the gastric acid to protect the bug. |
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Term
| how is the ulcer developed? |
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Definition
| stomach acid eats away stomach lining. May eventually promote stomach cancer |
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Term
| what is the best way to diagnose for H. pylori? |
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Definition
| swallow isotopically labeled Urea (because it will be broken down by Urease) and the same carbon will show up in CO2 that is expired |
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Term
| what are the distinguishing physical features of Campylobacter jejuni? |
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Definition
|
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Term
| how does Campylobacter cause disease? |
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Definition
| penetrates cells of intestine and secretes (heat-labile) entertoxin causing diarrhea |
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Term
| What syndrome may develop from infection with C. jejuni? |
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Definition
|
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Term
| what happens in Guillain-Barre syndrome? |
|
Definition
| cross-reactivity that causes autoimmunity against myelin on peripheral nerves. |
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Term
| where do infections come from? |
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Definition
| animal (they are zoonotic). Poultry is responsible most of the time (one drop of juice from raw chicken can cause infection) |
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Term
| do you have bloody stools with C. jejuni? |
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Definition
| yes, it is an invasive infection |
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