Dose

quantity of a drug taken or given

Dose Expressions

Quantity (25mg, 5ml, 250mg/ml)

Amt per kg of body wgt (5mg/kg)

Amt per sq m BSA (10mg/m^2 BSA)

Advantages of dosages based on body size (wt. or BSA)

Helpful in determining pediatric doses and adult doses for certian drugs (esp. drugs w/ narrow therapeutic indicies and those used in radiopharmaceuticals)

Dosage Regimens

Gives the name and quantity or concentration of a drug w/ frequency of schedule of administration

Name the Dosage Regimen:

Diazepam 2mg tid

Name and quantity of drug with frequency of administration

Name the Dosage Regimen:

Diazepam 6mg per day in 3 divided doses

Name and quantity of drug w/ frequency of administration

*CAUTION: this example is often misread as 6mg/dose in 3 doses/day--TID is the intended dose!

Name the Dosage Regimin:

Hydrocortisone cream 2.5% apply BID

Name and concentration of drug w/ frequency of admininstration

Name the Dose Regimen:

Haloperidol 10 mcg/kg TID

Name and quantity of a drug per kg of body wt w/ frequency of administration

Name the Dose Regimen:

Haloperidol 30mcg/kg/day in 3 divided doses

Name and quantity of drug per kg of body wt w/ frequency of administration

*CAUTION: Be wary of misreading this equivalency equation; it's not 30mcg/kg TID

Name the Dose Regimen:

Haloperidol 1mg/m^2 BSA TID

Name and quantity odf drug per m^2 of BSA w/ frequency of administration

Name the Dose Regimen:

Haloperidol 3mg/m^2 per day in 3 divided doses

Name and quantity of drug per m^2 of BSA w/ frequency of administration

*CAUTION: Read equivalency equations carefully; this is not 3mg/m^2 BSA TID