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Calcium channels in synaptic transmission
synaptic transmission calcium channels neuro tim
8
Biochemistry
Graduate
09/23/2010

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Cards

Term
what kind of gates are calcium channels?
Definition
N type voltage gates
Term
what irreverisbly blocks calcium channels?
Definition
W conotoxin
Term
what causes calcium channesl to rapidly open?
Definition
action potential
Term
what are 2 things that Calcium does once it enters the cell
Definition

binds to calcinerurin

binds to calmodulin

Term
what is calcineurin?
Definition
protein that closes the ca channel once it binds to calcium
Term
what are 2 ways the calcium is made unavailable inside the cell?
Definition

calcineurin turns close the Ca gate

calcium pumps stop and phosphatases inactivate synapsin I

Term
what is calmodulin?
Definition
calmodulin is a protein that binds to calcium and becoems CAM kinsase II
Term
what is the fxn of CAM kinase II?
Definition
CAM kinase II phosphorylates synapsin I causing it to "let go" of actin and therefore allow neurotransmitter to fuse to the membrane
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