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Broad Spectrum Agents
Broad Spectrum Agents
6
Pharmacology
Professional
08/19/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Name the broad spectrum agents
Definition
Chloramphenicol
Term
Is Chloramphenicol a common drug?
Definition
Rarely used due to side effects
Term
MOA of chloramphenicol
Definition

reversibly binds to 50s ribosomal subunit of susceptible organisms inhibiting protein synthesis.

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Term
antibiotic activity of chloramphenicol
Definition
Activity against gram (+), gram (-), anaerobes, and atypicals.
Term
Black box warning for chloramphenicol
Definition

serious and fatal blood dyscrasias (aplastic anemia, thrombocytopenia) - must monitor CBC

 

Term
Dose adjust chloramphenicol in renal impairment?
Definition
Yes.
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