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Breast
Diagnostic Medical Sonography
227
Medical
Not Applicable
10/20/2011

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Term
Thelarche
Definition
dev't of breasts (age 10-12)
Term
L boob
Definition
Which boob is usually larger?
Term
Release of estrogen and progesterone by ovaries
Definition
What causes the breasts to dev't?
Term
hypothalamus
Definition
Thelarche is controlled by ?
Term
Precocious Puberty
Definition
secondary sexual characteristics before the age of 8
Term
Endocrine malfunction
Definition
Percocious puberty is a ? malfunction
Term
80-85%
Definition
How much of the breast tissue is fat?
Term
Axilla
Definition
underarm fossa containing lymph nodes, lymph drainage channels, blood vessels and nerves
Term
subcutaneous fat
mammary or glandular layer
retro mammary fat
Definition
What are the three layers between the skin and pectoralis major musle?
Term
mammory layer
Definition
what layer contains the functional portion of the breast and supporting or stromal layer?
Term
15-20
Definition
Parenchymal layer has ? lobes separated by fat/fibrous tissue
Term
hundres of throusands
Definition
Each lobe contains lobules, how many lobulees within each breast
Term
1-8mm
Definition
How large is each lobule
Term
30-50
Definition
How many ducts are in each lobule
Term
Alveolus
Definition
another name for TDLU?
Term
TDLU's
Definition
The ends of acini form small units called
Term
1-2mm
Definition
TDLU's are ? in size
Term
TDLU
Definition
Nearly ALL pathologic processes that occur in breast occur in the
Term
stroma
Definition
What is dense connective tissue, loose connective tissue and fat?
Term
Cooper's Ligaments
Definition
What maintains shape and structure of the breast?
Term
suspensory (cooper's) ligmaments
Definition
Stretching of the ? causes sagging?
Term
areola and nipple
Definition
What structures are made up of pigmented squamous epithelium?
Term
Mongomery's Glands
Definition
What are the small bumps (sebaceous glands) on the areola called
Term
Sappey's plexus
Definition
The base of the nipple is surrounded by a circular band of smooth muscle
Term
Meyerholtz's muscle
Definition
Longitudinal smooth muscle fibers are?
Term
Internal mammary
Definition
Areterial supply that feeds the central, medial half of the breast, pec major and minor
Term
Lateral thoracic a.
Definition
Arterial branch that feeds the upper outer portion
Term
2x
Definition
How much more blood does the arterial supply of the upper breast get over the lower half?
Term
metastatic spread
Definition
? migrate to axillary, intercostal and internal thoracic veins, hence lung involvement and skeletal involvement
Term
SVC syndrome
Definition
35-year-old with a 3-year history of progressive upper-extremity and fascial swelling. The patient had hx of breast Ca . CT scan shows a narrowed superior vena cava with adjacent calcified lymph nodes and posterior soft tissue thickening, what is the best differential?
Term
Thoraco-dorsal n
Definition
? innervates the superior half of latissimus dorsi m
Term
Thoracic n
Definition
? supplies the serratus anterior m
Term
Intercostal brachial n
Definition
Three nerves that supply the skin of the medial surface of upper arm
Term
Deep lymph channels
Definition
What drainage route drains most of the breast?
Term
Axillary
Definition
What portion of the breast has no functional breast tissue?
Term
lymph node
Definition
ovoid,
Ovoid, hypoechogenic rim with fatty hilum
Term
Axilla
Definition
What lies in the supero-lateral chest wall and upper arm
Term
pec major and fascia
Definition
The superficial layer of muscle contains?
Term
pec minor, subclavius, clavipectoral
Definition
deep layer of muscles include?
Term
Gynecomastia
Definition
enlargement of the male breast
Term
fluid transport
Definition
What is the primary function of the breast?
Term
Acini
Definition
Milk is produced where?
Term
estrogen
Definition
Ductal system proliferates under the influence of ?
Term
pituitary gland
Definition
Prolactin is controlled by the ?
Term
Progesterone
Definition
? suppresses milk production
Term
hypothalamus, pituitary gland
Definition
Oxytocin is produced by ? and secreted by ?
Term
reduce
Definition
What happens to the density of brasts post menopause
Term
increased
Definition
Asian and japanese women have ? density of the breast
Term
skin
Definition
no more than 3 mm in thickness
Term
premammary
Definition
Skin
Nipple
Areola
Suspensory ligament extensions
Subcutaneous fat
-make up what layer?
Term
more
Definition
Nipple and areola attenuate sound <> than the surrouding breast tissue
Term
subcutaneous fat
Definition
What depends on body habitus, age, parity and hormonal status?
Term
low
Definition
Fat lobules in breast are ? reflectors and display darker than the glandular tissue
Term
hypo
Definition
Fatty breast = ?-reflective = not good for ultrasound
Term
hyper
Definition
Coopers ligaments are hypo/hyper reflective
Term
middle mammary
Definition
functional breast tissue, glandular, lactiferous
ducts and interconnecting tissues
include TDLU's
-what layer of breast is this?
Term
hyperreflective
Definition
old ppl have ? boobs
Term
hyporeflective
Definition
young ppl have ? boobs
Term
retromammary
Definition
Sits anterior to chest wall
Pectoral Muscles
Ribs
-this breast layer is ?
Term
atrophy
Definition
in post menopausal women, ducts, lubules and glandular tissue ?
Term
MLO= medial lateral oblique
CC = cranial caudal
Definition
What are the two positions of mammo test
Term
Under 35 years of age
Implants
Pregnant or lactating
Men
Suspected abscess, open wound
Axillary symptoms
Suspected benign process present
Definition
Reasons to get an ultrasound instead of mammo
Term
Palpable lump
Further investigation of Mammographic finding
Insufficient mammogram due to location of lesion
For interventional guidance
Definition
Reasons to do both mammo and US
Term
Suspected silicone implant leak
Defining presences of multifocal lesions, metastatic lesions
High risk women with below adequate mammographic imaging i.e. VERY dense breasts or Scarring from previous surgeries
Definition
Reasons for whole breast US
Term
Pain
Diffuse nodularity
No clinical abnormality and negative mammography
Definition
Ultrasound is not done for
Term
high
Definition
Optimal transducers are ? frequency
Term
40%
Definition
? of malignancies have multiple focal lesions
Term
same quadrant/breast
Definition
Multifocal means?
Term
more than one quadrant/breast
Definition
Multicentric means?
Term
benign
Definition
? lesions push planes apart
Term
malignant
Definition
? lesions invade planes
Term
2mm
Definition
A duct is considered dilated when the measurement is >? mm
Term
3mm
Definition
What measurement defines the skin as thickened?
Term
Round/spherical, oval, ellipsoid
Definition
shape of benign
Term
Smooth, lobulated, encapsulated
Definition
Borders of benign
Term
well defined, well circumscribed
Definition
Margin definition of benign
Term
anechoic, slightly hyporeflective, hyper/isoreflective
Definition
Internal reflectivity of benign
Term
homogeneous, uniform
Definition
Reflectivity pattern of benging
Term
Enhancement, edge shadow
Definition
Through transmission of benign
Term
Mobile
Definition
Mobility of benign
Term
Wider than taller, horizontal or round, parallel to chest wall
Definition
Depth-width ratio of benign
Term
Simple cyst
Definition
What cyst is defined as asymptomatic, tender, round/oval, anechoic with through transmission
Term
Complex cyst
Definition
What cyst is defined as asymptomatic, tender, irregular thick wall, hypoechoic w/o transmission
Term
oil cyst
Definition
What cyst is defined as a result of surgical or accidental trauma with palpable anechoic mass
Term
Galactocele
Definition
What cyst is defined as a palpable mass during pregnancy or lactation, anechoic with fat-fluid level
Term
Sebaceous cyst
Definition
What cyst is defined as smooth, superficial palpable mass, anechoic with through transmission
Term
Fibroadenoma
Definition
What benign neoplasm is asymptomatic, firm, rubbery, mobile, wider than taller, macrolobulated
Term
Cystosarcoma phylloides
Definition
What benign neoplasm is palpable, firm, mobile, rapidly enlarging, contains cystic spances
Term
Papilloma
Definition
What benign neoplasm results as nipple discharge, small solid mass within cyst or dilated ducts
Term
Lipoma
Definition
What benign neoplasm is soft, mobile, compressible, asymptomatic, isoechoic
Term
Invasive ductal carcinoma
Definition
What malignant neoplasm is hard, fixed, palpable, skin changes, speculated mass, posterior shadowing
Term
Invasive lobular carcinoma
Definition
What malignant neoplasm causes breast thickening, irregular borders with heavy posterior shadow and asymptomatic
Term
Colloid (mucinous carcinoma)
Definition
What malignant neoplasm is soft, causes skin changes, hypoechoic, microlobulated, well defined
Term
Medullary carcinoma
Definition
What malignant neoplasm is discrete, mobile, rapidly enlarging, hypoechoic, round
Term
Papillary carcinoma
Definition
What malignant neoplasm causes nipple discharge, palpable mass, solid
Term
Metastatic carcinoma
Definition
What malignant neoplasm is hard, round, mobile, rapidly enlarging, hypoechoic masses
Term
Inflammatory carcinoma
Definition
What malignant neoplasm causes mastitis, increase in tissue echogenicity and skin thickening
Term
irregular
Definition
Malignant shape and contour
Term
irregular, infiltration, spiculated
Definition
malignant margin/border
Term
ill defined
Definition
malignant margin definition
Term
hyporeflective
Definition
malignant internal reflectivity
Term
heretogeneous, varied
Definition
malignant reflectivity pattern
Term
reduced, central shadowing
Definition
malignant through transmission
Term
fixed, immobile
Definition
malignant mobility
Term
rigid
Definition
malignant compressibility
Term
taller than wider, vertical, perpendicular to chest wall
Definition
malignant depth to width ratio
Term
20-50%
Definition
Breast cysts occur in _-_% of women in reproductive years
Term
40-50
Definition
Peak breast cysts occur in age _-_?
Term
No
Definition
Does HRT affect breast cysts?
Term
oral contraceptives
Definition
What lower the risk of dev'p breast cysts
Term
therapeutic and diagnostic
Definition
What are two reasons to aspirate a cyst
Term
galactocele
Definition
Milk filled retention cyst, dev'p in pregnancy or lactation, palpable nodule
Term
fibroadenoma
Definition
Most common benign solid breast tumor
Term
fibroadenoma
Definition
Most commonly diagnosed breast tumor in women younger than 30
Term
Fibroadenoma
Definition
Arise from TDLU, grow profusely, bilateral
Term
cystosarcoma phyllodes
Definition
most common non-epithelial tumors, rapidly grow, usually benign, mid 40's
Term
phyllodes
Definition
What presents with firm, mobile, well circumscripbe, rapidly enlarging, hypervascular
Term
lipoma
Definition
presents as slow growing, fatty soft tissue throughout the body, hyperechoic, asymptomatic
Term
benign breast disease
Definition
symptoms: fullness, tenderness, pain varying with cycle, vague nodulatity
Term
bilateral
Definition
is benign breast disease (unilateral, bilateral)
Term
benign breast disease
Definition
women in mid to late 30's most affected
Term
increased density, decreased sensitivity
Definition
what happens to the density and sensitivty on mammography for BBD
Term
higher
Definition
ultrasound has a ? sensitivity in dense breast tissue
Term
honeycomb appearance
Definition
Benign Breast Disease has what type of appearance on US
Term
hyperechoic with no posterior shadow
Definition
microcystic disease has ? tissue with ? shadow
Term
microcystic disease
Definition
individual and blusters of riny (2-3mm) are seen; small calcification sometimes seen
Term
fibrocystic disease
Definition
disease shows cysts and ductal ectasia (dilation), some with echoes within that appear solid
Term
intraductal papilloma
Definition
symptom: nipple discharge, bloody discharge, disrupts architecture
Term
premenopausal, younger
Definition
single intraductal papilloma lesions appear subareolar and are found in ? patietns whereas multiple papilloma lesions are on the periphery and found in ? patients
Term
juvenile papillomatosis
Definition
seen in adolescence, dilated ducts with echoes within that are papilloma made up and look like swiss cheese
Term
aren't
Definition
intraductal papilloma are/aren't seen on mammo
Term
intraductal papilloma
Definition
slightly hypoechoic, solid mass within duct
Term
simple cyst
Definition
20-50% of women in reproductive years, peak in 40-50's
Term
simple cyst
Definition
duct obstructions with fluid accumulation in a localized spot, HRT doesn't affect, oral contraceptives shown to reduce
Term
simple cyst
Definition
most likely the culprit of a palpable lump
Term
theraputic and diagnostic
Definition
two reasons a cyst would be aspirated
Term
galactocele
Definition
milk filled retention cyst, dev'p in pregnancy/lactation, palpable
Term
galactocele
Definition
well-defined, internally complex cyst, high fat content of fluid gives hyoerechoic echo texture, cyst with distal dilated duct
Term
fibroadenoma
Definition
most commonly diagnoised breast tumor in women younger than 30
most common benign solid breast tumor
Term
TDLU's due to hyperplasia
Definition
fibroadenoma's arise from ?
Term
fibroadenoma
Definition
grows rapidly, exceeding 10cm, bilateral, arise from TDLU's, well circumscribed, hyperechoic margin, hypoechoic internal margin, through transmission
Term
children
Definition
who are affected by giant fibroadenoma
Term
phyllodes
Definition
rare, benign, make up .3% of breast tumors, mid 40's, rapidly growing
Term
phyllodes
Definition
firm, mobile, well-circumscribed, non-tender, rapidly enlarging, oval shapped with smooth margins, hypervascular
Term
lipoma
Definition
common, 1% population, slow growing, fatty soft tissue throughout body, asymptomatic, palpable, mobile, well defined
Term
hamartoma
Definition
overgrowth of glandular, adipose and fibrous tissue, 30+ yrs, well circumscribed, septated
Term
tubular or lactating adenoma
Definition
containing acini that are packed together, predominately epithelial lesions
Term
pseudoangiomatous stromal hyperplasia (PASH)
Definition
rare, premenopausal women, abnormal cell groth due to progesterone stimulation, palpable painless mass,
Term
infarct
Definition
outgrowth of blood supply, too heavy of a metabolic demand, tenderness, fixed
Term
radial scar/sclerosing lesion
Definition
asymptomatic, cellular proliferation and hyperplasia, adenosis around a fibro-elastic center, architectural distortion
Term
mastitis
Definition
most are staphylococcal infection
Term
young smokers
Definition
periareolar mastitis affects what types of patients
Term
peripheral mastitis
Definition
? mastitis (less common) associated with diabetes, rhumatoid arthritits, steroid tx, or trauma
Term
Lymphocystic Lobulitis (Diabetic Mastopathy)
Definition
rare autoimmune reaction, occurs in insulin dependant diabetes, palpable central mass, ill defined
Term
good
Definition
hematoma will have internal echoes but ? through transmission
Term
granulomas
Definition
tissue growth at trauma site, oval, homogeneous
Term
lymphadenopathy
Definition
enlargement with or w/o loss of cortico-hilar differentation, corticol thickening, prominent but normal looking
Term
insitu or invasive
Definition
two types of malignant breast disease
Term
classifications of malignant
Definition
asymmetric thickening, unilateral pain, localized, non-cyclic, discharge from single duct and blood stained, unilateral nipple retraction, skin changes
Term
non-invasive in situ disease
Definition
15-20% of breast maalignancies are ?
Term
LCIS
Definition
arises from the epithelium in the ducts, more prevelenat in the younger population of reproductive years, multifocal, bilateral,
Term
papillary CA
Definition
central ducts, retroareolar, with serous or bloody discharge, focal solid lesion w/in lumen of duct, non-invasive if stay within ducts, 90% 5 yr survival rate
Term
tubular CA
Definition
evidence of LCIS and DCIS, seen with radial scar, middle aged women, slow growing, hypoechoic, irregular shape, central shadow, taller than wider
Term
mucinous (colloid) Ca
Definition
rare, slow growing, older women, cells floating in extracellular mucin
Term
medullary ca
Definition
rapidly growing, increased association with BRCA1 and BRCA2 genes
Term
Invasive Ductal Ca (NST)
Definition
75% are not in the previous types of carcinomas, 70% palpable masses, 36% seen on mammo
Term
no special type (NST)
Definition
Why is Invasice Ductal Ca called NST
Term
NST
Definition
solid lesion, irregular margins, possible microcalcifications, halo or hypoechoic rim, dense, posterior shadow
Term
invasive lobular carcinoma
Definition
2nd most common invasive carcinoma, 12-15% breast cancer, bilateral, full mastectomy result
Term
>1cm
Definition
when malignancy is suspected, nodes are greater than ?
Term
lose hypoechoic center
Definition
when is a lymph node considered abnormal?
Term
multifocal
Definition
multiple tumors in same quadrant
Term
multricentric
Definition
multiple lesions within the same breast
Term
40%
Definition
? % of breast cancer malignancies have ipsilateral multifocal/multicentric disease
Term
3%
Definition
?% of breast cancer are bilateral
Term
cosmetic
Definition
70-80% of breasts implants are done because?
Term
20-30%
Definition
?% are used to correct congenital or traumatic deformity and for reconstruction following mastectomy
Term
1960's
Definition
breast impants were first used in ? year
Term
single
Definition
single or double lumen: silicone gel or saline encapsulated in silicone shell
Term
double
Definition
single or double lumen: inner silicone-filled lumen and smaller outer saline filled lumen
Term
prepectoral, retropectoral
Definition
most cosmetic impants are ? but there is also a ?
Term
No documented increase risk of cancer or neurological or autoimmune disorders
Definition
are there any risks of implants for cancer or autoimmune disorders
Term
No speed artifacts with saline
Definition
What is the benefit of saline implants?
Term
well-defined, hyperechoic
Definition
implant surface (well-defined, ill-defined) and (hypoechoic, hyperechoic
Term
no
Definition
is the fibrous capsule seen separetely from the implant
Term
Capsular Contraction
Definition
? contraction presents as pain, hardness, tension or squeezing sensation, reduced mobility, disfigurement
Term
Capsular Hypertrophy
Definition
Possibly results from a pronounced immune response to a gel bleed
›50% of older implants
Term
Surgical Scaring
Definition
Mimics malignancy-hypoechoic with central shadowing
Term
Silicone Granuloma (siliconoma)
Definition
Collection of silicone within breast tissue
›Caused by rupture or gel bleed
Hyper-reflective lesion, similar to lipoma but with a snow-storm affect posterior
Term
Silicone Granuloma (siliconoma)
Definition
Collection of silicone within breast tissue
›Caused by rupture or gel bleed
Hyper-reflective lesion, similar to lipoma but with a snow-storm affect posterior
Term
implant rupture
Definition
>2/3 of implants age 10-20 years
Term
intracapsular
Definition
silicone is outside the implant but contained within the fibrous capsule
Term
Extracapsular
Definition
silicone is found outside of the fibrous capsule
Term
snowstorm
Definition
extracapsular has what type of US appearance
Term
Intracapsular
Definition
Step ladder appearance
Free floating implant shell
Term
Lymph nodes affected with silicone are hyperechoic with “snowstorm” and posterior shadowing
Definition
What happens to lymph nodes of a silicone leak
Term
MRI
Definition
What is the gold standard for diagnosing patients with implants
Term
Hypoechoic fat with hyperechoic connective tissue within
Definition
What does the male breast look like on ultrasound
Term
Gyocomastia
Definition
40% of all male breast disorders
Simple hyperplasia of breast parenchyma
Imbalance in the effects of estrogen and testosterone on the breast tissues
Term
Gynocomastia
Definition
Increased estrogen or decreased androgen levels
Enlargement due to subareolar duct development and surrounding tissue
Term
Acute Gynocomastia
Definition
hyperplasia of ductal epithelia and myoepithelial tissue

◦Hypoechoic area, deep to nipple, irregular, ill-defined and spiculate. Normal fat distorted
Term
intermediate gynocomastia
Definition
? phase-seen histologically, change in ducts, and fibrosis of surrounding tissue

◦Hypoechoic mass deep to nipple, heterogeneous tissue, may have shadowing,
Term
chronic gynocomastia
Definition
similar to normal female breast tissue, usually not tender, hard mass felt
Term
lipoma
Definition
male breast disorder of Soft, round/oval palpable mass, hyperechoic mass
Term
malignant
Definition
If a male cyst is complex, it is more likely to be
Term
male breast cancer
Definition
1700 diagnosed cases in US annually
67 yrs old average
BRCA2 mutations in 4-14%
Term
Invasive Ductal Carcinoma IDC
Definition
Most common type of male breast cancer is ? occuring in 93.7% of cases
Term
male breast cancer
Definition
Focal mass, spiculate, hypoechoic, posterior shadowing, disrupt planes.
Can be well-circumscribed, slightly hypoechoic
Term
Mammo
Definition
? is gold standard for screening, surveillance and symptomatic
Term
higher
Definition
Tissues that attenuate the signal more have a ? atomic number
Term
lower
Definition
? atomic number = ? attenuation and hence are more black, sub q and fat
Term
more, whiter
Definition
Denser the tissue, ? attenuation, ? on film
Term
MRI
Definition
Protons and magnetic field aligns with the scanner’s field
Term
malignancies, benign
Definition
Typically ? show strong focal enhancement, rapid contrast uptake and early washout, usually opposite with ?
Term
Radionuclide Imaging (RNI)
Definition
Demonstrates biochemical tissue characteristics and gives info regarding functional changes associated with disease processes
Term
Scintimammography Imaging (RNI)
Definition
Helps find multicentric or contralateral disease, in assessing tumor response to chemo, and sensitive to disease reoccurrence
Term
SPECT
Definition
Collection of radionuclide activity into in multiple planes, producing discrete cross-sectional slices of the patient
Term
PET
Definition
Duel head gamma camera, detects simultaneous detection of pairs of gamma rays, when positrons combine with electrons
Allows detection of the location of the emitting radionuclide to within 3 mm
Term
sentinel nodes
Definition
Lymph nodes that receive the initial lymphatic drainage from a tumor site are known as the ?, can be multiple
Term
sentinel node localization
Definition
Detects the presence of tumor in lymph nodes
Term
lung, bone and liver
Definition
Most common sites for breast metastases is ?? and ?
Term
Cytology
Biopsy
Definition
? for fluid
? for solid
Term
kissing
Definition
Introducer needle placed, “?” the nodule, Bx needle will pass through this.
Term
parallel
Definition
Needle needs to be ? to chest wall all times
Term
Pneumothorax
Definition
puncture of chest wall into lung
Term
Pseudoaneurysm
Definition
if a vessel is punctured
Term
Usually patient follow-up done via phone the next day to assure no complications
Definition
How are breast bx follow ups usually addressed
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