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Brainstem - Intro
N/A
73
Medical
Graduate
03/22/2013

Additional Medical Flashcards

 


 

Cards

Term
What condition is caused by the compression of the superior colliculus due to a tumor of the adjacent pineal gland?
Definition
Parinaud Syndrome (paralysis of upward gaze)
Term
Name the region of the cortex that controls voluntary eye movements.
Definition
Frontal Eye Fields (rostral to primary motor cortex)
Term
What syndrome is caused by blockage of PICA?
Definition
Wallenberg's Syndrome (dorsal-lateral medullary)
Term
List the clinical features that characterize Wallenberg's Syndrome.
Definition

IPSIlateral loss of pain and temperature from FACE

CONTRAlateral loss of pain and temperature from BODY

Term
Which two cranial nerves, within the auditory meatus, are served by the labyrinthine artery?
Definition

VII

 

VIII

Term

List the cranial nerves and whether they are:

- motor, sensory, and/or parasympathetic

- if sensory, what is the peripheral sensory ganglion

- if parasympathetic, in which ganglion does the postparasympathetic neuron reside?

Definition
p. 187 - CP
Term
[image]
Definition
Third Nerve Palsy
Term
[image]
Definition

Anterior Aternating Hemiplegia (Weber's Syndrome)

 

- ipsilateral opthalmoplegia

- controlateral hemiparesis

 

if corticobulbar is involved:

 

- contralateral paralysis of lower face, tongue, and trapezius

Term
[image]
Definition

Claude's Syndrome

 

Red Nucleus = motor control

 

- ipsilateral opthalmoplegia (CN III)

- contralateral hemiparesis (descending corticospinal tract)

- contralteral paralysis of lower face, tongue, and shoulder (corticobulbar tract)

 

Term
Given the orientation of PSNS and somatic motor fibers within CN III, what effects will compression and ischemia have?
Definition

Compression: pupillary deficit alone

 

Ischemia: somatic motor deficits alone

Term
Describe the path of CN IV from the trochlear nucleus as it exits the brainstem.
Definition
axons travel dorsally---->around periaqueductal gray----------->CROSS---->exit from dorsal surface---->between superior cerebellar and posterior cerebral aa.
Term
How is a distal CN IV lesion distibuished from a lesion closer to the trochlear nucleus?
Definition

Distal lesion - affects ipsilateral eye

 

damage to nucleus - affects contralateral eye

Term
[image]
Definition
Compensatory response to Nerve IV Palsy - head is tilted to side of normal eye.
Term
A patient with nerve IV palsy would have difficulty performing which 2 tasks?
Definition
reading and walking down stairs
Term
Vascular insufficiency of which arteries could cause sixth nerve palsy?
Definition

Basilar

Basilar aa. branches - Circumferential (serving pons)

Term
Why is CN VI especially susceptible to compression injuries?
Definition
It courses over a bony ridge.
Term
[image]
Definition

VI Nerve Palsy

 

convergent strabismus (affected eye turned in)

compensation: turn hear toward affected side

Term
[image]
Definition

Middle Alternating Hemiplegia

 

- ipsilateral opthalmoplegia (VI n. palsy)

 

- contralateral hemiplegia (CST)

 

- dysarthria (tongue) - CBT

Term
Describe the events of the near response.
Definition

- eyes move in the opposite direction (vergence)

- pupillary constriction

- increased accommodation

Term
What controls vergence movements?
Definition
Bilateral input from supraoculomotor nucleus to the oculomotor nuclei.
Term
What controls horizontal gaze?
Definition

Paramedial Pontine Reticular Formation

PPRF

Term
What drives the PPRF and what does it project into?
Definition

driven by contralateral frontal eye fields



projects to ipsilateral abducens nucleus

Term
Describe how horizontal gaze is achieved once the abducense nucleus receives input from the PPRF
Definition

some abducens nn--->innervate lateral rectus mm



remaining abducens nn--->cross midline--->ascend as medial longitudinal fasciculus--->contralateral occulomotor nucleus--->medial rectus of that eye

Term
Describe the voluntary neural control of vertical gaze
Definition
bilateral inpur from FEF--->to riMLF--->occulomotor and trochlear nuclei
Term
What causes parinaud syndrome (paralysis of upward gaze)?
Definition
compression of the superior colliculus
Term
Describe thevestibulo-ocular reflex pathway.
Definition
[image]
Term
What are the effects of a lesion in the left vestiular nerve or nuclei?
Definition

- right vestibular nuclei becomes dominant

 

- eyes drift to the left but snap back to rightright-beating nystagmus

 

left-staggering gait

Term

Describe the effects of lesion #1.

 

[image]

Definition
[image]
Term

Describe the effects of lesion #2.

 

[image]

Definition
[image]
Term

Describe the effects of lesion #3.

 

[image]

Definition
[image]
Term

Describe the effects of lesion #4.

 
[image]
Definition
[image]
Term

What is the following lesion known as? What are its effects?

 

[image]

Definition
[image]
Term
What test is used to test the integrity of the vestibular pathways? Describe the results of the test.
Definition
[image]
Term

Describe the syndrome characterized by the following:

 

- Ptosis

- Pupillary constriction (miosis)

- Anhidrosis (lack of sweating) on the face

Definition
[image]
Term
How is minor/early compression of CN III distinguished from a vascular insult?
Definition

compression - affects peripherally located parasymp. fibers---->pupillary deficit

 

vascular insult - somatic nerve fibers located more centrally----->eye movement deficit

Term
Which different types of sensory information is relatyed to the sensory cortex via the VPL nucleus and the VPM nucleus?
Definition

VPL - sesnsory info from body

 

VPM - discriminatory touch, conscious propioception, vibration from face and oral cavity

Term

Describe the pathway that conveys the following information from the head.

 

- pain/temperature

 

- touch/pressure

Definition

pain/temperature: primary neurons in trigeminal ganglion--->secondary neurons in chief sensory nucleus of V--->VTT (crosses midline) or DTT--->VPM--->primary sensory cortex

 

touch/pressure: primary neurons in trigeminal ganglion--->turn caudally within brainstem to form spinal tract of V---> VTTcrosses midline--->VPM--->primary sensory cortex

Term
Which CN's receive sensation from the ant. 1/3 of the tongue and the post. 1/3 of the tongue?
Definition

ant. 1/3 = CN V

 

post. 1/3 = CN IX

Term
Which 4 CN's project to the spinal nucleus of V--->VTT (crosses over)--->VPM--->sensory cortex?
Definition
CN V, VII, IX, and IX
Term
Which three CN's receive stimuli for the corneal (blink) reflex?
Definition

CN II - bright lights

CN VIII - loud noise

CN V - direct corneal contact

Term
Which CN stimulates the closure of the eyes during the corneal reflex and what is the result of a lesion in the efferent arm of this nerve?
Definition

CN VII

 

lesion: loss of reflex from ipsilateral eye

Term
What is trigeminal neuralgia?
Definition

Pain of unknown origin associated with V2 or V3 mostly.

 

Treatment: cut pain and temperature fibers within spinal tract of V.

Term
Which 3 CN's convey taste and from where?
Definition

CN VII - Ant. 2/3 of tongue

CN IX - Post. 1/3 of tongue

CN X - Epiglottis

Term
What is the effect of a lesion in the rostral nucleus solitarius or tract?
Definition

ipsilateral loss of taste

 

cause message is carried through uncrossed solitariothalamic tract to VPM

Term
A lesion to which nucleus results in the loss of the gag reflex?
Definition
nucleus ambiguus (LMN)
Term
What lesion is indicated by the deviation of the uvula to the normal side?
Definition
lesion in nucleus ambiguus (loss of motor innervation to levator veli palatini)
Term
What lesion results in deviation of the uvula to the affected side?
Definition
lesion in UMN corticobulbar input; cause - crossed pathway.
Term
What is the effect of bilateral damage to the nucleus ambiguus and why?
Definition

complete laryngeal paralysis

death

loss of gag reflex

Term
Describe the gag reflex pathway.
Definition
sensory info to spinal nucleus of V--->bilateral projection to nucleus ambiguus--->efferent limb of reflex
Term

State whether the following muscules have a primarily contralateral or ipsilateral UMN drive.

 

- Trapezius

 

- SCM

Definition

Trapezius - contralateral



SCM - ipsilateral

Term
A lesion in the right CN XI will cause the head to turn to which side? Which shoulder will be affected?
Definition

right side - cause lesion causes paralysis of right SCM, which normally rotates head to the left.

right shoulder sags - cause lesion causes paralysis of right trapezius

Term
UMN lesions will cause weakness in which SCM and trapezius muscle?
Definition

ipsilateral SCM

contralateral trapezius

Term
A unilateral lesion of the hypogloassal nucleus or tract will cause deviation of the tongue to which side?
Definition
to the affected side (cause of paralysis and atrophy of musculature ipsilateral to side of lesion)
Term
An UMN lesion will result in deviation of the tongue to which side of the lesion?
Definition
contralateral side of the lesion (cause corticobulbar input to hypoglossal nerve is crossed)
Term
[image]
Definition

Inferior Alternating Hemiplegia

 

ipsilateral paralysis and deviation of tongue

contralateral hemiparesis

Term
An UMN lesion will cause deviation of the uvula to which side?
Definition

ipsilateral side of lesion

(cause of palatal weakness on contralateral side of lesion, allowing muscles in ipsilateral side to dominate) 

 

[image]

Term

Which vessels supply blood to the following regions

- inner retina

- outer retina

Definition

inner: central retinal aa and vv

outer: long and short posterior cilliary aa

Term
What is the pathway of flow of aqueous humor?
Definition
enters posterior chamber from cilliary process vasculature--->through pupil into anterior chamber--->through trabecular meshwork into vv
Term
What is high intracoluar pressure known as?
Definition
glaucoma
Term
Name the 3 cell types of the direct pathway and the 2 cell types of the indirect pathway.
Definition
[image]
Term
Why are rods more sensitive, with less spatial resolution than cones?
Definition

rods: high convergence---->single photon has better chance of activating retinal ganglion cell

[image]

Term

Which PhR cell responds to the following light ranges?

- scotopic-mesopic

- mesopic-photopic

Definition
rods and cones (respectively)
Term
Describe the dark current and what changes occur within the cell under in light.
Definition

[image]

[image]

Term

What type of cone bipolar cell is described below?

"responds to an increase in illumination vs. background

Definition
on cell
Term

What type of cone bipolar cell is described below?

"responds to a decrease in illumination vs. background"

Definition
off cell
Term
Describe the events of phototransduction in the rod system when exposed to light
Definition
rod hyperpolarization--->rod bipolar depolarization--->amacrine cell depolarization--->ganglion on cell depolarizedoff cell hyperpolarized
Term
Describe the events of phototransduction in the cone system when exposed to light
Definition
cone hyperpolarized--->on bipolar cells depolarized, off bipolar cells hyperpolarized--->on galnglion depolarized, off ganglion cell hyperpolarized
Term
What information are amacrine cells involved in the analysis of?
Definition
detection of movement and directionality of movement
Term
Distinguish between linear and non-linear spatial responses of ganglion cells.
Definition

linear: ganglion cell responds to specific phase (light or dark) of light

 

non-linear: ganglion cell responds to change in phase (light to dark or vice versa)

Term

List the 3 types of RGCs and their

- location in the retina

- spatial resolution

- function

Definition

Midget (80%) (P-cells)

fovea mostly; high spatial res.; detail analysis

red-green

 

Parasol (10%) (M-cells)

least in fovea; low spatial res.; detection of motion

achromatic

 

Small Bistratified

uniform distribution; unknown spatial res.

yellow-purple

Term
To which cell layers do the large, parasol and midget RGCs project to within the LGN?
Definition
magnocellular (M-cell) and parvocellular (P-cell) layers respectively
Term

Describe the dorsal-ventral location of the following fibers within the optic radiations.

- superior visual field (inferior retina)

- inferior visual field (superior retina)

Definition

- ventral

- dorsal

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