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Brain Exam #2
Brain developments, PTSD, Depression
58
Biology
Undergraduate 1
03/11/2009

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Term
Day 18 of fetal development
Definition
nervous system forms out of ectoderm. Become neural tube
Term
Day 28 of fetal development
Definition
Neural tube forms fore, mid and hind brain regions.
Term
3-4 weeks of in-utero development
Definition
primary neurulation: ectoderm and neural tube
Term
3-4 months of in-utero development
Definition
neuronal proliferation. Birth of neurons in the brain. Yet to be assigned
Term
3-5 months of in-utero development
Definition
neuronal migration: cells travel on astrocyte/micro-glia fiber, encountering chemicals which assign them to their specific working place in the brain.
Term
5 months-postnatal development
Definition
Organization: axon development of neurons, full cell maturation, pruning.
Term
Birth-postnatal
Definition
mylenation: strengthening of synapses, quicker communication, acquiring new skills.
Term
Synapses of newborns
Definition
very few and slow. As age progresses the number of synapses increases exponentially and become more efficient. Experencies of first year strengthen synapses and prune others.
Term
Babies and language
Definition
newborns up to one year have the ability to decipher the differences in phonemes in different languages. Lose the ability after 1 year because they learn their own native language.
Term
Center for speech comprehension
Definition
Wiernickes area
Term
Center of speech production
Definition
Broca's area
Term
Phonology
Definition
speech sounds
Term
morphology
Definition
word form
Term
syntax
Definition
sentence structure
Term
sematics
Definition
word and sentence meanings
Term
prosody
Definition
intonation and rhythm of speech
Term
pragmatics
Definition
use of language
Term
Key component of language acquistion
Definition
Mimicry
Term
Mirror neurons
Definition
neurons that fire in response to an action and also upon observing of the same action when carried out by someone else. Also when read a sentence describing something. Located in Broca's area
Term
Roles of Mirror Neurons
Definition
reading intention: fire when observing something we expect to happen.
reading and feeling emotions and communicating them to others: seeing the look on others faces fire mirror neurons and allow for us to perceieve their reaction and emotion.
Term
Mirror Neurons and Autism
Definition
Autism may be accounted for by an inactive mirror neuron system. Explains the inability to understand other's emotions, language production and communicating.
Term
Plasticity
Definition
the neurons ability to change, adapt or be molded. Early detection of autism can allow for intervention of neuron plasticity and increase chance of communication.
Term
Adolescence: brain maturation
Definition
2nd wave/burst of neuron proliferation. Accounts for time of identity, emotions and maturity.
Term
First section of brain to develop in adolescence
Definition
Limbic system: hippocampus, amygdala. learning, memory, emotions, nucleus accumbus, behavioral responses
Term
Slower section to develop in adolescence
Definition
Frontal lobes: thinking, planning, attention, decision making, understanding consequences, social functioning. judgement
Term
The Case of Phineus Gage
Definition
Rod from accident severed the pathway of communication between the frontal lobes and limbic system. Resulted in volitile mood swings, loss of intuition, poor decisions, "thinking before speaking."
Term
Reward System
Definition
Network of neurons that active when we perform survival tasks or other things that pleasure us. Food, drink, sex, chocolate...anything. drugs
Term
Drug abuse and reward system
Definition
Drugs give the same feeling of euphoria as the reward system gives when performing a pleasurable task. Mask bad feelings. Reward system becomes overwhelmed and receptors are hidden making for larger and larger amounts of drugs needed to get a good feeling.
Term
Reward system parts
Definition
Nucleus accumbens recieves dopamine for pleasurable tasks, giving good emotional response.
Term
Amino Acids
Definition
glutimate, gaba, glycine
Term
Amines
Definition
Epinephrine, dopamine
Term
Peptides
Definition
endophines
Term
Cocaines affect on reward system
Definition
cocaine bonds to dopamine and makes it linger longer in the synapses. longer feeling of euphoria
Term
Opiates affect on reward system
Definition
taps into endophines. blocks the release of inhibitory neurons for dopamine.
Term
Heroine and Nictoine effect on reward system
Definition
releases more dopamine
Term
Alcohol affect on reward system
Definition
blocks inhibitory neurons from cleaning up or limiting dopamine
Term
Female brain in adutlhood
Definition
larger limbic system, frontal cortex, hippocampus. greater ability to remember details and language center
Term
Male brain
Definition
larger amygdala and parietal lobes. higher concentration on emotinos including fear, anxiety, and stress. as well as spatial perception.
Term
Difference in male/female brains
Definition
due to steroid hormone stiumlation in fetal development
Term
Adult brain
Definition
memory development, problem solving skills, planning and inhibition-- peak performance
Term
Cannon-Bard theory of emotional perception
Definition
upon seeing something the brain/ neocortex processes the emotional response appropriately- travels to hippocampus where appropriate action is remembered- physical response to emotion- conveyed through thalamus back to neocortex
Term
James-Lange theory
Definition
Upon seeing something the physical response first reacts-- thalamus conveys message-- neocortex processes physical reaction--hippocampus remembers instances that relate to same.
Term
What do Cannon-Bard and James-Lange have in common
Definition
that the hypothalamus and neocortex affect one another.
Term
Hypothalamus
Definition
master regulator of mammal stress response
Term
Short term stress
Definition
Nerve cell signals adrenal gland to secret epinephrine.
----- increase glucose, heart rate, breathing, alertness, slow digestion and kidneys
Term
Long term stress
Definition
amygdala tells hypothalamus to release CRH which travels to the pituitary gland which releases ACTH to the adrenal gland which secrets cortisol. ---increase blood pressure, glucose,
Term
stress shut down system
Definition
cortisol after released appropriately returns to the hypothalamus and signals it to stop. Likewise when ACTH is released, it returns to hypothalamus to say stop.
Term
Effect of CRH on hippocampus
Definition
long term damage on hippocampus in CRH overdose causes hippocampus to not be able to calm hypothalamus which causes more CRH...endless cycle.
Term
Depression and cortisol
Definition
depression patients have high levels of CRH and cortisol in their system causing stress, fatigue, loss of apetite, depletion of sex drive and insomnia, chronic phobia.
Term
Anatomy of depression
Definition
frontal cortex is less active while Area 25 is hyperactive. there is a break of communication between frontal cortex and limbic system which can account for aggression.
Term
Diffuse modulatory system in depression
Definition
serotonie system- raphe nuclei
neroepinephrine system- locus coeruleus
Term
Melancholic unipolar depression
Definition
40-50% of cases, bad in the morning, anorexia, insomnia
Term
atypical unipolar depression
Definition
15% of cases, worse in the evening, overeating, oversleeping
Term
dysthmia unipolar depression
Definition
lasts over a period of years, mild
Term
Role of antidepressants
Definition
block the re-uptake or break down of serotine or neorepinephrine in the synapses. Linger feeling of good feelings.
Term
Bipolar depression
Definition
periods of depression interrupted by periods of mania. energy, motivation, creativity, psychosis, money binge.
Term
Lithium
Definition
balances the intensity of negative (depressed) and positive (manic) sides of bipolar depression.
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