Term
|
Definition
| mimic the natural effects of neurotransmitters |
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|
Term
|
Definition
| inhibit the natural effects of nuerotransmitters |
|
|
Term
|
Definition
| produce the opposite of the natural effects of neurotransmitters |
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|
Term
| If a natural NT produces EPSP an antagonist would __________. While an inverse agonist would _____________. |
|
Definition
-prevent the EPSP then nothing else
-produce an IPSP |
|
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Term
| List three ways drugs could alter your neuron's functions: |
|
Definition
-altering the synthesis
-altering the type of NT released from the axon terminal
-could block or stimulate NT release at the presynaptic receptors |
|
|
Term
List drug example(s) for each type of alteration:
-synthesis
-type of NT released
-blocking/stimulating release |
|
Definition
synthesis: AMPT, ChAT
type released: ampehtamines, Botox
blocking/stimulating: caffeine in reference to adenosines |
|
|
Term
amphetamines
-agonist of catecholamine |
|
Definition
| stimulate release of catecholamines (by opening calcium channels), blocks reuptake |
|
|
Term
acetylcholinesterase (AChE)
-agonist of acetylcholine |
|
Definition
| breaks down acetycholine(ACh, causes muscle conteaction), inhibited by pesticides, nerve gas |
|
|
Term
benzodiazepines
-agonist of GABA
-antagonist of everything else |
|
Definition
| neuromodulators/ enhance GABA effects (benzo + GABA = opens Cl gates so hyperpolarization occurs a.k.a. IPSP) |
|
|
Term
Botox
-antagonist of acetycholine |
|
Definition
| blocks the release of ACh |
|
|
Term
caffeine
-antagonist to adenosine |
|
Definition
| "disinhibition"; blocks adenosine inhibition of glutamate release |
|
|
Term
capcaisin
-agonist to substance p |
|
Definition
| presynaptic facilitiation of Substance P release |
|
|
Term
|
Definition
| blocks reuptake of catecholamines |
|
|
Term
enkephalin
-antagonist of substance P |
|
Definition
| presynaptic inhibition of Substance P release |
|
|
Term
|
Definition
| cholinergic receptor agonist |
|
|
Term
Prozac
-antagonist of serotonin |
|
Definition
| blocks reuptake of serotonin |
|
|
Term
alcohol
-agonist of GABA
-antagonist of everything else |
|
Definition
| neuromodulator/ enhances GABA effects |
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