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Bone
MCAT
33
Other
Not Applicable
03/10/2005

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Cards

Term
compact bone
Definition
dense bone with no cavities
Term
spongy bone/cancellous bone
Definition
much less dense than compact bone; consists of inteconnecting lattice of bony spicules. Cavities filled with yellow or red bone marrow
Term
yellow marrow
Definition
inactive, and infiltrated by adipose tissue
Term
red bone marrow
Definition
involved in blood cell formation
Term
diaphysis
Definition
cylindrical shaft of long bones. Composed primarily of compact bone surrounding a cavity containing bone marrow.
Term
epiphyses
Definition
dilated ends of long bones. Composed of spongy bone surrounded by a thin layer of compact bone.
Term
epiphyseal plate
Definition
disk of cartilaginous cells separating the diaphysis from the epiphysis; site of longitudinal growth.
Term
periosteum
Definition
fibrous sheath that surrounds the long bone; is the site of attachment to muscle tissue. Some cells differentiate into bone-forming cells.
Term
bone matrix
Definition
Composition of compact bone. Dense, hardened, contains both organic and inorganic components.
Term
components of bone matrix
Definition
Organic: proteins (collagen fibers and glycoproteins)
Inorganic: calcium, phosphate, hydroxide (which combine to form hydroxyapatite crystals), and sodium, potassium, magnesium ions.
Term
hydroxyaptite crystals
Definition
hydroxide aggregates. Association of these crystals with collagen fibers gives bone its strength.
Term
osteons (Haversian systems).
Definition
Bony matrix is deposited in these structural units. Each consists of Haversian canal, lamellae, and lacunae.
Term
Haversian canal
Definition
central microscopic channel in osteon, containing blood vessels, nerve fibers, lymph, which vascularize and innervate bone tissue.
Term
lamellae
Definition
Concentric circles of bony matrix which surround the Haversian canal.
Term
lacunae
Definition
spaces within matrix, which house osteocytes. Canaliculi radiate from each.
Term
osteocytes
Definition
involved in bone maintenace.
Term
canaliculi
Definition
Radiate from each lacuna. They interconnect with each other and the Haversian canals, allowing for exchange of nutrients and wastes.
Term
osteoclasts
Definition
Large multinucleated cells that break down bone; (bone resorption)
Term
osteoblasts
Definition
cells that build bone. Synthesize and secrete organic constituents of the bone matrix; mature into osteocytes once surrounded by their matrix.
Term
Osteoporosis
Definition
Disease caused by loss of bone mass due to increased osteoclast resorption and slowing of bone formation. Estrogen helps prevent by stimulating osteoblast activity.
Term
endochondral ossification
Definition
bone formation occurs by this process. Existing cartilage is replaced by bone. Long bones arise primarily through this process.
Term
intramembranous ossification
Definition
A type of bone formation process. mesenchymal connective tissue is transformed into, and replaced by, bone.
Term
mesenchymal connective tissue.
Definition
embryonic, undifferentiated (connective tissue)
Term
bone reformation
Definition
inorganic ions (calcium and phosphate are absorbed from the blood for use in bone formation.
Term
bone resorption
Definition
Degradation of bone. Calcium and phosphate are released into blood.
Term
bone remodeling
Definition
bone reformation and bone resorption
Term
joints
Definition
connective tissue structures that join bones together.
Term
immovable joints
Definition
bones that do not move relative to each other and are held in place, such as skull bones.
Term
movable joints
Definition
bones that do move relative to one another; additionally supported and strengthened by ligaments. Consist of synovial capsule, movement is facilitated by synovial fluid and articular cartilage.
Term
ligaments
Definition
Strengthen and support movable joints.
Term
synovial capsule
Definition
Part of movable joints. ncloss a joint cavity (articular cavity)
Term
synovial fluid
Definition
Lubricates the joint and facilitates movement.
Term
articular cartilage
Definition
On the opposing bone surfaces of the join; smooth, reduces tension during movement.
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