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Bone
Bone
24
Biology
Graduate
11/26/2012

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Term
Osteoprogenitor cells
Definition
stem cells that become Osteoblasts
Term
Osteoblast
Definition
-makes matrix
-cuboidal or round shape
Term
Osteocytes
Definition
-deposit bone
-have long processes that sense stress
-transport Ca between blood and bone
Term
Osteocytes
Definition
-erode bone, release Ca and PO4 into blood
-have integrin proteins
Term
Howship's Lacunae
Definition
-cavities in bone formed by osteocytes
Term
Osteopotin
Definition
-protein that binds to integrin on osteocytes
-forms a seal for howship's lacunae
Term
hydroxyapatite crystal
Definition
calcium + phosphorus
Term
another name for compact bone
Definition
lamallar
Term
another name for spongy bone
Definition
cancellous or trabecular
Term
another name for bone
Definition
woven bone
Term
what is contained in the periosteum?
Definition
Osteoblast, Osteoprogenitor, fibroblasts, collagen
Term
Haversian Systems
Definition
-sleeves of bone that forms around a blood vessel
-occurs in compact bone
Term
Volkman’s canal
Definition
-alt. type of lamellar arrangement in compact bone
-runs perpendicular to Haversian systems
Term
Interstitial
lamellae
Definition
what's left of haversian systems that are being built over
Term
Intramembranous bone formation
Definition
-bones form from mesenchyme
-ex: flat bones of the skull, part of the clavicle
and the collar of long bones
Term
Endochondral bone formation
Definition
-Bone forms from an existing piece of
hyaline cartilage
-ex: all long bones and many flat bones
Term
Growth hormone
Definition
-Regulator of bone growth
-stimulates production of insulin-like growth factor-1 (IGF-1) that stimulates bone formation.
Term
Estrogen
Definition
-Regulator of bone growth
-prevents bone loss
-closes epyipseal plates at puberty
Term
Testosterone
Definition
-Regulator of bone growth
-stimulates bone growth
Term
Calcitonin
Definition
-Regulator of bone growth
-inhibits osteoclasts
Term
Mechanical Stress
Definition
-Regulator of bone growth
-stimulates bone growth
-inhibits osteoclasts
Term
PTH
Definition
-Regulator of bone growth
-stimulates osteoclasts
-but given at low dose, stimulates bone growth
Term
Thyroid Hormone
Definition
-Regulator of bone growth
-stimulates bone growth in children
-causes osteosporosis in high doses
Term
Vit D
Definition
-Regulator of bone growth
-stimulates osteoclasts
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