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BMS FINAL
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Aerospace Engineering
Undergraduate 2
12/07/2012

Additional Aerospace Engineering Flashcards

 


 

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Term
Innate Immunity
Definition
Immediate response, general defense against infection, no memory (Macrophages and Dendritic cells)
Term
Adaptive Immunity
Definition
takes longer, specific response to pathogens, memory cells produced (T & B cells)
Term
Physical Barriers
Definition
Skin, part of first line of defense, mucus membrane, tears, sweat, skin bacteria
Term
Chemical barriers
Definition
high pH to get rid of bacteria/pathogens, saliva, tears, sweat
Term
Neutrophils
Definition
Most abundant WBC, First responders, phagocytes
Term
Basophil
Definition
Found in blood, WBC, Releases histamine to cause inflation
Term
Eosinophil
Definition
WBC, target parasitic infections, allergy
Term
Mast cell
Definition
Found in tissues, releases histamine
Term
Dendritic cell
Definition
Phagocyte, WBC, mobilize adaptive immunity
Term
T-cells
Definition
kill abnormal body cells and activate B cells (Cell mediated Immunity)
Term
B-cells
Definition
Make protein anitbodies, produced in Red bone marrow, antibody mediated immunity
Term
4 functions of lymphatic system
Definition
Drainage (Absorb excess fluid)
Delivery (Absorb fat)
Disposal (Transport foreign material to lymph nodes)
Defense (helps defend body against pathogens)
Term
Lymph vascular system
Definition
one way valve system that carries fluid.
Capillaries(take up excess fluid)
Vessels(muscle compressions move fluid)
Thoracic/Right lymphatic duct two main "Highways"
Term
What does Lymph system produce?
Definition
White blood cells
Term
Vital Lymphatic organs (2)
Definition
Red Bone marrow (B cell maturation)
Thymus (t cells multiply and mature, produce thymosin)
Term
Secondary lymphatic organs (4)
Definition
Lymph Nodes (filteration)
Tonsils (Filter lymph)
Spleen (Filter blood)
Peyer's patch/appendix (pathogens in Intestines)
Term
4 key players in 2nd line of defense
Definition
phagocytic WBC
Complement protein
Inflammatory response
Fever (pos. feedback)
Term
Complement protein (2 pathways of destruction)
Definition
1. Mark pathways for destruction, suicide mission
2. Form pores in wall of pathogen, cell bursts
Term
Inflammatory response
Definition
Cytokine releases/activates complement proteins
Histamine released
Macrophages respond to marked pathogens and eat them
Term
Four hallmark symptoms of inflammation
Definition
redness/heat (increase blood flow/temp)
Swelling/pain (Excess fluid pressure)
Term
Vital Capacity
Definition
Forced Inhalation + tidal vol + forced exhalation
Term
Four key features of Adaptive immunity
Definition
Recognition of self vs. nonself
Specificity (B/T cells only make one type of antigen)
Diversity (need to recognize more than one pathogen)
Memory (reserve cells for future)
Term
MHC markers
Definition
label body cells as not pathogen
Term
Two types of T cells
Definition
Cytotoxic T cells: Kill!
Helper T cells: release cytokines to promote b cell activity
Term
Effector cells
Definition
act right away, undergo apoptosis when finished killing pathogen
Term
Memory cells
Definition
Act in future infections
Term
Clonal Expansion
Definition
B & T cells divide after an interaction with a pathogen
Term
Antigen presenting cells (3)
Definition
Macrophages, B cells, Dendritic cells.
Term
Antigen presenting cells process
Definition
engulf cell, cut into peices, display marker, cell mediated immunity begins
Term
IgG
Definition
Main antibody can cross plasma
Term
IgA
Definition
Abundant in tears, saliva, milk, mucus
Term
IgE
Definition
allergic reactions
Term
IgD
Definition
B cell receptor
Term
IgM
Definition
10 places to attach, 1st secreted during immune response, can be secreted
Term
Periform
Definition
make holes in infected cell's membranes
Term
What causes rejection of tissue
Definition
Cytotoxic T cells
Term
Immunosuppressants
Definition
make no immune system, prone to infection except in cornea/testes
Term
Active immunity
Definition
Long lasting, natural infection (chickenpox) Vaccination
Term
Passive immunity
Definition
short lived, passed from mother to fetus/mother to infant/injections
Term
Monoclonal antibody
Definition
antibodies made in the lab by cells cloned from plasma B cell
Term
immunotherapy
Definition
cytokines activate B/T cells to treat disease, stops cell division
Term
Anaphylactic shock
Definition
whole-body allergic response
Term
Steps leading to allergic response
Definition
1.allergy enters body
2. B cells recognize/bind to
3. Helper T cells secrete cytokines
4. Clonal expansion of B cell
5. Effector B cell produce IgE
6. IgE attachs to mast cell
7. Mast cells release histamine and cytokine
Term
Autoimmune disorders (3)
Definition
Rheumatoid arthritis
Type 1 diabetes (no insulin)
Systemic lupus (attacks whole body)
Term
Immunodeficiency
Definition
weakened or missing immune system
Term
severe combined immune deficiency
Definition
inherited, T cells not developed properly, kills infants
Treatment: bone marrow transplant or gene therapy
Term
Retrovirus
Definition
instructions in form of RNA not DNA
Term
HIV/what does it kill?
Definition
kills lymphocytes, macrophages, and Helper T cells, let in by accident because written into DNA
Term
Three things for AIDS patient
Definition
1. HIV positive
2. severely compromised immune system
3. Indicator disease
Term
Virulence (3)
Definition
1. how fast invades body
2. degree of damage
3. antibiotic resistance
Term
4 ways a pathogen spreads
Definition
1. Direct contact (body fluid)
2. Indirect contact (shower)
3. Inhaling pathogen
4. Contact with flies/ticks/fleas
Term
Epidemic
Definition
disease rates increase above predicted level
Term
Pandemic
Definition
Epidemic breaks out over several countries
Term
Sporadic disease
Definition
breaks out irregularly
Term
Endemic
Definition
Common cold, occurs more or less continuously
Term
Pathway of Air
Definition
Nose-epiglottis-pharynx-larynx-trachea-bronchus-bronchioles-aveoli
Term
nose functions
Definition
warms/filters air
Term
Pharynx
Definition
throat; connects larynx and esophagus
Term
parietal/visceral pleura
Definition
mucus that covers lungs to allow it to glide over each other while lungs contract and relax
Term
Aveoli
Definition
Where gases diffuse between lungs and blood capillaries, provide large surface area
Term
Respiration
Definition
occurs in alveoli, exchange of inhaled oxygen and CO2
Term
What diffuses down a concentration gradient?
Definition
O2 and CO2, partial pressure gradient. Thin walls of aveoli allows this
Term
Hemoglobin
Definition
when it binds in RBC to O2 it helps maintain the pressure gradient that draws air into lungs
Term
What maintains pressure gradient??
Definition
Removing oxygen from the lungs!!
Term
Hypoxic
Definition
tissue chronically short of oxygen, hyperventilation occurs
Term
Inspiration
Definition
active process of inhalation that brings air into the lungs
Term
Expiration
Definition
passive process of exhalation that expels air from the lung
Term
Inspiration process
Definition
1. diaphragm and external intercostal muscles contract
2. diaphragm flattens, rib cage moves up
3. air pressure in lungs decreases
4. air flows from outside in
Term
Expiration process
Definition
1.Diaphragm and external intercostal muscles relax
2. diaphragm moves upward
3. ribcage moves down
4. vol of thoracic cavity and lungs decrease
5. air pressure in lungs increases
6. air flows out of lungs
Term
Tidal volume
Definition
normal breath (500 mL)
Term
Inspiratory reserve vol
Definition
forcefully inhale-3100 mL
Term
Expiratory reserve vol
Definition
forcefully exhale-1200 mL
Term
Residual vol
Definition
amount left in lungs after forceful exhale, 1200 mL
Term
Vital Capacity
Definition
inspiratory reserve vol + expiratory reserve vol + tidal vol= 4800 mL
Term
total lung capacity
Definition
5000-6000 mL
Term
Cellular respiration (internal)
Definition
Gas exchange between systemic capillaries and tissue fluid (cells), use oxygen to make energy. Produces CO2
Term
Whole body respiration (external)
Definition
exchange of gases with the atmosphere, occurs between pulmonary capillares and alveoli
Term
Cell respiration equation (buffer system)
Definition
CO2+H20=H2CO3=HCO3+H
Term
Carbonic anhydrase
Definition
On surface of RBC, starts hemoglobin cellular respiration cycle
Term
Where does buffer system begin?
Definition
surface of RBC because thats where the enzyme is
Term
What carries the majority of CO2 in the blood plasma?
Definition
Bicarbonate ions
Term
medulla oblongata
Definition
controls breathing from the brain, sends out nerve impulses to contract muscles
Term
What monitors CO2 concentration to control breathing?
Definition
Sensors from arteries monitor CO2, O2, and blood pH
Term
vagus nerve
Definition
controls pharynx & larynx, breathing, heart beat
Term
Phenic nerve
Definition
goes to and controls diaphragm
Term
what else control air flow and blood flow (2)
Definition
1. diameter of bronchioles
2. Diameter of alveoli capillaries
Term
Respiratory disorders (4)
Definition
Bronchitis
Emphysema
Asmtha
Apnea
Term
Pathogens/cancer in respiratory system (4)
Definition
Pneumonia
Influenza
Tuberculosis
Histoplasmosis
Term
squamous cell carcinomas
Definition
cancer in cells lining aveoli
Term
adenocarcinomas
Definition
cancer in ducts/lungs
Term
Large cell carcinomas
Definition
any epithelial cell
Term
small cell carcinomas
Definition
most aggressive form of cancer
Term
Five major functions of digestive system
Definition
1. mechanical processing and mobility
2. secretion
3. digestion
4. absorption
5. elimination
Term
Pathway of food
Definition
mouth-pharynx-larynx-esophagus-stomach-small intestine-large intestine-rectum-anus
Term
Food
Definition
considered only when in mouth,uses mechanical ways of chewing to break down food
Term
Bolus
Definition
chewed mass of food in pharynx and esophagus
Term
Chyme
Definition
soupy food mixture in stomach and small intestine
Term
Feces
Definition
poop in large intestine, rectum, anus
Term
where are carbs, lipids,nucleic acid, and proteins digested?
Definition
small intestine
Term
Major components of digestion (8)
Definition
mouth, pharynx, esophagus, stomach, small intestine, large intestine, rectum, anus
Term
Accessory organs of digestion (4)
Definition
salivary glands, liver, gallbladder, pancreas
Term
4 layers of esophagus inside out
Definition
1. Mucosa (epithelial tissue)
2. submucosa (connective tissue)
3. muscularis (smooth muscle)
4. Serosa (epithelial tissue)
Term
Mechanical digestion
Definition
begins in mouth, chewing (mastication), tongue helps for bolus
Term
Chemical digestion
Definition
mix food with saliva, starch digestion begins in mouth
Term
Salivary analyse
Definition
digests starch
Term
swallowing voluntary phase
Definition
beginning of food being swallowed until pharynx
Term
Involuntary phase of swallowing
Definition
once food in pharynx, epiglottis covers voice box food moves down
Term
Peristalsis
Definition
rhythmic contractions move food
Term
3 major functions of stomach
Definition
1. mix/store ingested food
2. produce secretion to break down food (protein digestion begins in stomach)
3. Controls food entering small intestine
Term
plyloric sphincter
Definition
controls food entering small intestine (valve)
Term
stomach
Definition
very acidic, contains gastric juices and converts bolus into chyme
Term
small intestine
Definition
site of completion of digestion, digested food absorbed through large surface area of microvilli
Term
How to digest fats?
Definition
must go from food into lacteal into blood
Term
Three accessory organs
Definition
Pancreas, liver, gall bladder
Term
Pancreas three parts
Definition
exocrine glands
endocrine glands
Pancreatic juice
Term
Exocrine gland in pancreas
Definition
secretes digestive enzymes
Term
Endocrine gland in pancreas
Definition
secretes hormones into blood
insulin (glucose to glycogen in liver)just ate
glucagon (glycogen to glucose)-no foo/sleep
Term
Pancreatic juices
Definition
bicarbonate to neutralize acidic chyme from stomach
Term
Liver functions
Definition
detoxifies blood, makes/secretes bile, makes B cell (plasma) antibodies, stores vitamins and glucose
Term
Gall Bladder function
Definition
stores excess bile that allows fats to emysify into water
Term
Fat absorption stages
Definition
fats need to be coated in bile salt then lipase digests it and is absorbed into bood.
Term
Digestive carb enzymes (3)
Definition
Salivary Amylase
Pancreatic Amylase
Maltase (makes small carbs into glucose)
Term
Digestive protein enzyme (3)
Definition
Pepsin
Trypsin
Peptidases (make single amino acid)
Term
Digestive fat protein enzyme
Definition
Lipase
Term
Digestive nucleic acid enzyme
Definition
Nuclease
Nucleosidase
Term
what enzyme functions best in a neutral environment?
Definition
Salivary Amylase (produced in mouth)
Term
Pancreatic amylase
Definition
small intestine
Term
Pepsin
Definition
stomach
Term
Trypsin
Definition
small intestine
Term
peptidase
Definition
small intestine
Term
lipase
Definition
small intestine
Term
nuclease
Definition
small intestine
Term
Nucleosidase
Definition
small intestine
Term
Function of large intestine
Definition
absorbs water and some vitamins
MAKES POOP
Term
Hormones that regulate digestion (3)
Definition
Gastrin
CCK
Secretin
Term
Gastrin
Definition
stomach, increases acid secretion
Term
CCK
Definition
Small intestine, stimulates gall bladder to release bile
Term
Secretin
Definition
small intestine, increases bicarbonate secretion by pancreas, slows contractions
Term
Gastroesophageal reflux disease
Definition
chronic heartburn
chyme backs up in esophagus
limit acidic foods
Term
Barrett's esophagus
Definition
precancerous condition
Term
3 parts of large intestine
Definition
Ascending colon
transverse colon
descending colon
Term
Constipation
Definition
hard to eliminate waste
Term
Diverticulitis
Definition
inflammation of the lining of large intestine
Term
Irritable bowel syndrome
Definition
disturbance of smooth muscle contractions
Term
Colon Cancer
Definition
#2 diagnosed cancer, easily treated if caught early, high fat low fiber
If polyp visible could be cancer
Term
Celiac disorder
Definition
gluten intolerance
Term
Cystic fibrosis
Definition
lacks digestive enzymes, difficult to digest
Term
Crohns disease
Definition
inflammation of intestinal lining
Term
Diarrhea (2 microorganisms)
Definition
Giardia intestinalis
E. Coli
Term
Heliobacter pylori
Definition
peptic ulcers open sores in stomach leads to gastritis and stomach cancer
Term
What carbs are the best?
Definition
Complex (starch)
Term
Glycemic index
Definition
measure of blood sugar for 2 hours after eating. Spikes after simple sugars
Term
Essential fatty acids
Definition
not able to be produced by liver (8 amino acids essential)
Term
Vitamins
Definition
organic substance, needed for growth and survival
Term
Minerals
Definition
inorganic substance
Term
4 fat soluble vitamins
Definition
A,D,E,K
Term
2 water soluble vitamins
Definition
C, B12
Term
4 minerals
Definition
calcium
iodine
iron
potassium
Term
3 antioxidant vitamins and purpose
Definition
A,C,E stop free radicals
Term
Goiter
Definition
lack or iodine
Term
muscle weakness
Definition
lack of potassium
Term
blood clotting
Definition
k
Term
what causes scurvy
Definition
C
Term
Four Tissues
Definition
Epithelia, connective, muscle, nervous
Term
Simple Squamous
Definition
lines blood vessels, lungs, gas exchange
Term
Simple Cuboid
Definition
lines glands and ovaries, filtration
Term
Simple Columnar
Definition
stomach intestines uterus; absorbs nutrients
Term
Pseudo stratified columnar
Definition
throat, nasal passage, sinuses, trachea, sweeps mucus
Term
Protein fibers
Definition
Collagen(flexibility and support)
Reticular(very thing cartilage)
Elastic(elasticity)
Term
Stratified Cuboidal
Definition
Ducts of sweat glands
Term
Stratified Squamous
Definition
skin, mouth, throat (protection)
Term
Basement membrane
Definition
anchor of epithelial tissue
Term
exocrine gland
Definition
substances released through ducts or tubes; sweat/mammary glands
Term
endocrine gland
Definition
Substance released directly into extracellular fluid, (hormone secretion)
Term
Transitional epithelia
Definition
able to stretch to allow for fluctuation in liquid, bladder
Term
matrix
Definition
ground substance+protein fibers
Term
Hyaline cartilage
Definition
strength/flex, nose, ends of long bones
Term
Loose areolar
Definition
Under the skin, elastic, fibroblasts and fibroclasts
Term
Loose adipose
Definition
Under skin/around organs, insulation, adipocytes
Term
Dense regular
Definition
Tendons (muscle to bone)
Ligaments (Bone to bone)
Term
Dense Irregular
Definition
Dermis of skin, cushion at all angles
Term
Elastic Cartilage
Definition
Stringy, outer ear, elastic
Term
Bone compact
Definition
middle of bones in shafts, protection, matrix
Term
Blood
Definition
transport 02, fights infection, clots blood, Plasma matrix
Term
Lymph
Definition
lymph nodes, where WBC congregate, aid in fighting infection
Term
Bone spongey
Definition
Ends of long bones, protection, matrix
Term
Skeletal
Definition
striated and voluntary, muscles
Term
Smooth
Definition
nonstriated and involuntary (stomach)
Term
Cardiac muscle
Definition
striations and involuntary (heart)
Term
Sensory Neuron
Definition
carries messages from PNS to CNS
Term
Interneuron
Definition
Integrates data, CNS only
Term
Motor neuron
Definition
Motor output, CNS to PNS to muscle/gland
Term
Neuron
Definition
allows communication between cells
Term
Neuroglia
Definition
90% of cells in nervous system
Term
Astrocyte
Definition
brings nutrients to neurons
Term
Microgilia
Definition
engulfs bacteria and cell debris
Term
Oligoendrocyte
Definition
Form myelin sheath in CNS (insulation)
Term
Schwann cell
Definition
Form myelin sheath in PNS (insulation)
Term
Tight junction
Definition
Block leaks in tissues, urine remains in kidney
Term
Adhering Junction
Definition
Glue, allows skin to stretch
Term
Gap junction
Definition
Channels that connect neighboring cells, interculated disks present,
Term
Mucous membrane
Definition
Secrete/absorb substances, lines tubes, ONE SHEET
Term
Serous membrane
Definition
PAIRED SHEETS, secretes protection fluid
Term
cutaneous membrane
Definition
skin membrane
Term
Synovial membrane
Definition
lines movable joint cavities, lubricates ends of bones, no friction
Term
Meningeal membrane
Definition
surround brain/spinal cord with cerebrospinal fluid
Term
Cranial
Definition
Brain
Term
Spinal
Definition
spinal cord
Term
thoracic
Definition
heart and lungs
Term
Abominal
Definition
stomach, live, gall bladder, pancreas, small intestine
Term
Pelvic
Definition
reproductive organs
Term
Epidermis (4)
Definition
stratified squamous
Keratinocyte (all dead cells)
Melanocyte (gives skin color)
Langerhan/Granstein (immune cells)
Term
dermis
Definition
Dense connective tissue, contains blood and nerve endings
Term
hypodermis
Definition
not part of skin, fat, insulator/cushion
Term
Skin disorders:
Definition
Acne, blisters, cold sore
Term
Skin cancer
Definition
Basal:least likely to spread
Melanoma: most likely to spread
Term
Regulators of homeostasis
Definition
Set point:Value required to maintain homeostasis
Sensory receptors:translates stimulus into a signal that can be sent to brain
Stimulus: specific change in environment
Integrator: brain
Effectors: muscle and gland
Term
Negative feedback
Definition
Activity alters condition in internal environment and triggers response to reverse condition (normal body temp/HR/Blood pressure)
Term
Positive feedback
Definition
Chain of events intensify a change from the original condition to reverse the change. EX- birth contractions, blood platelet,
Term
Endotherms
Definition
Make heat from within
Term
hypothalmus
Definition
controls body temperature
Term
Specialized cells
Definition
Adipocytes, chondrocyte
Term
Fibrocartilage
Definition
knee joints, strength and support, collegan to withstand stress
Term
integumentary system
Definition
protects body from injury and dehydration, receives sensory information
Term
Heart
Definition
Generates Blood pressure, regulates blood pressure
Term
Capillaries
Definition
Exchanges nutrients and waste
Term
Lymphatic system
Definition
Collects excess extracellular fluid, returns fluid to CV system
Term
Septum
Definition
Thick wall that divides heart in half
Term
Chambers of heart (thick/thin)
Definition
Atria (Thin)
Ventricles (thick)
Term
Coronary arteries
Definition
Branch off aorta
Term
Atrioventricular valves
Definition
Tricusid
Bicuspid
Term
Heartbeat
Definition
one cycle of contractions and relation of heart
Term
Cardiac Cycle
Definition
1. Atrial systole (Contract)
2. Ventricular systole
3. Cardiac Diastole (relax)
Term
Lub-Dub
Definition
Lub- AV valves closing
Dup- semilunar valves closing
Term
Cardiac output
Definition
every 60 sec, amount of blood pumped, 5 liters
Term
Pulmonary Circuit
Definition
RIGHT side of heart brings deoxygenated blood from the body to the lungs (get O2) and bring back to heart
Term
Systemic circuit
Definition
LEFT side of heart takes OXYGENATED blood to entire body to deliver nutrients and rid of waste
Term
Hepatic artery
Definition
Carries O2 rich blood to liver
Term
Mesenteric artery
Definition
Carries o2 to small intestine
Term
Hepatic portal vein
Definition
nutrient rich, oxygen poor
Term
Hepatic vein
Definition
back to the heart
Term
Intercalated disks
Definition
in cardiac muscle, communication junctions
Term
Sinoatrial node (SA node)
Definition
cardiac pacemaker of the body
Term
blood pressure
Definition
fluid pressure that blood exerts against vessel walls
Term
Hypertension
Definition
Elevated blood pressure
Term
hypotension
Definition
low blood pressure
Term
blood vessel flow
Definition
Artery-arteriole-capillary bed-venule-vein
Term
Blood pressure (where highest and lowest)
Definition
Highest: arteries (aorta)
Lowest: Vein (inferior vena cava)
Term
Blood flow (fastest to slowest)
Definition
Fastest: Arteries
Slowest: Capillares, takes time for nutrients and wastes to exchange
Term
3 layers of arteries
Definition
Outer layer (Collagen)
Middle layer(smooth muscle)
Inner layer (simple squamous)
Term
Pulse
Definition
surge of blood flow
Term
Are capillaries always open?
Definition
No, only open during certain times like eating
Term
Precapillary Sphincter
Definition
REGULATES FLOW OF BLOOD
smooth muscle,relaxes capillary=bed opens
Contracts=closes
Term
Medulla
Definition
monitors resting blood pressure
Term
Vasodilation
Definition
dilatation of blood vessels, which decreases blood pressure
Term
Vasoconstriction
Definition
The constriction of blood vessels, which increases blood pressure.
Term
Baroreceptor reflex
Definition
keeps blood pressure within normal limits if sudden change occurs, found in neck and aorta
Term
Venules
Definition
small branch of vein, receives O2 depleted blood and return to heart
Term
Veins
Definition
large diameter/low resistance, transports blood back to heart
Term
Valve
Definition
Prevents backflow of blood
Term
Blood reservoir
Definition
Collection of bloo, hol about 70% of blood
Term
CV disease/disorder risk factors
Definition
Genetics, obese, age, lots of transfat
Term
Atherosclerosis
Definition
cholesterol build up, LDL, HDL, transfat
Term
Atherosclerotic plaque
Definition
narrowing of artery
Term
Arteriosclerosis
Definition
hardening of artery
Term
Ways to repair blockage in arteries
Definition
Coronary bypass
Aneurysm (Ballooning)
Laser angioplasty
Term
Arrythmias
Definition
irregular heart rhythm
Term
Bradycardia
Definition
Slow heart rhythm
Term
Tachycardia
Definition
Fast heart rhythm
Term
Ventricular fiibrillation
Definition
cardiac arrest
Term
Heart cancers/disease
Definition
Rheumatic fever: infection of heart valves
Lyme disease
Myocardial: heart inflammation
Term
Blue babies
Definition
Hole in heart, fixed with surgery
Term
Heart cancer?
Definition
Rarely the first sight of cancer, VERY RARE
Term
Blood is a......
Definition
CONNECTIVE TISUE
Term
Formed elements
Definition
Erythrocyte (RBC)
Leukocyte (WBC)
Thombocyte (Platelet)
Term
Plasma & where it's made
Definition
Blood matrix, made in liver
Term
3 types of plasma protein
Definition
Albumin-Most abundant, osmotic pressure
Globulin-alpha, beta, gamma (WBC) (TRANSPORT HORMONES, CHOLESTEROL, COPPER
Fibrinogen- blood clotting
Term
Erythrocyte
Definition
120 days, most abundant, carry O2, CO2, H; contain hemoglobin, don't consume any O2 they carry
Term
Lungs environment
Definition
High levels of )2
Relatively cool
pH neutral
Term
How much o2 can hemoglobin carry?
Definition
depends on amount of O2, Temp of tissue and pH of tissue
Term
Structure of Hemoglobin
Definition
from protein globin, contains iron
Term
What do RBC loose to make room for hemoglobin?
Definition
Nucleus and other organelles
Term
Erythroprotein (EPO)
Definition
Hormone produced by kidney cells, helps stimulate RBC production, relies on negative feedback loop
Term
RBC disorders
Definition
Anemia: RBC don't deliver enough O2
Sickel cell: misformed
Thalassemia: Abnormal hemoglobin, fragile RBC
Term
Leukocyte
Definition
WBC, can live for years, defense and clean up of tissues, circulates in tissue
Term
Granylocyte
Definition
WBC- contains granules, basophil, neutrophil (abundant) Esoinophils
Term
Agranylocyte
Definition
Lacks granules, monocyte, SECOND MOST ABUNDANT WBC
Term
Neutrophil
Definition
use phagocytes to eat pathogens
Term
Eosinophil
Definition
Help stop parasitic infection, small percentage of WBC
Term
Basophil
Definition
Release histamine relate to allergic reaction
Term
Lymphocytes (three types)
Definition
B lymphocyte- antibody mediated immunity
T Lymphocyte-cell mediated immunity
NK (natural killer)- destroy cancer cell
Term
Monocyte (two kinds)
Definition
Macrophages- Phagocyte in tissue/blood. eat big things
Dendritic- phagocyte in skin
Term
WBC disorders
Definition
Infectious mono
Leukemia
HIV
Term
How many geno/pheno types?
Definition
4 pheno
6 geno
Term
Antigen
Definition
foreign substance that triggers immune response
Term
Antibody
Definition
binds to antigen and removes it
Term
agglutination
Definition
mixing of incompatible blood types
Term
What happens when Rh- mom has Rh+ fetus?
Definition
Hemolytic disease of the newborn
Term
What drug stops Hemolytic disease of the newborn?
Definition
Rhogam
Term
Autologuous transfusion
Definition
pre-donation of own blood before a surgery in case something goes wrong
Term
Megakaryocyte
Definition
Live one week, made in red bone marrow, produce platelets, function in blood clotting
Term
Hemostasis
Definition
prevents blood loss,
-injury to blood vessel
-spasm to vessel wall
-platelets come to site
Serotinin prolongs spasm
-clot forms
POSITIVE FEEDBACK
Term
Intrinsic Clotting
Definition
Involves substance IN THE BLOOD, for little injuries like paper cuts
Factor X(catalyzes thrombin with fribrinogen)
Thrombin
Fibrinogen
Fibrin
Term
Extrinsic Clotting
Definition
Release substance OUTSIDE THE BLOOD, a lot faster, for severe trauma
Term
Wound healing
Definition
phagocyte comes to site
scab formed
No infection
Scab forms
Term
Blood clots
Definition
Thrombus (blocks bloo flow)
Embolus (dislodged clot blocks blood flow)
Term
Hemophilia
Definition
Blood doesnt clot properly
Term
Thrombocytopenia
Definition
not enough platelets
Term
Septicemia
Definition
MRSA, poison blood, destroy RBC
Term
Toxemia
Definition
Metabolic poisons in the body, organ not working correctly.
Term
X factor
Definition
catalyzes thrombin with fibrinogen
Term
Charge of DNA
Definition
Negative
Term
Nucleotides
Definition
Adenine, Guanine, Thymine, Cytosine
Term
Term associated with having one different nucleotide in DNA sequence
Definition
single nucleotide polymorphism
Term
What occurs in a restriction enzyme cut site they create
Definition
Restricion fragment length polymorphism
Term
Two factors that affect migration of DNA through agrose gel?
Definition
Size of DNA, buffer, voltage, agrose concentration
Term
Restriction enzyme
Definition
enzyme that cuts dna at specific locations known as restriction sites
Term
What is the special type of DNA sequence restriction enzymes recognize
Definition
palindrome sequence
Term
What restriction enzyme did we use?
Definition
ecoR1
Term
DNA Ladder
Definition
allow people to determine the approximate size of DNA fragments
Term
DNA migration
Definition
moves to positive side of gel, small fragments move faster
Term
Law of segregation
Definition
alleles randomly separate and unite during fertilization
Term
Sex-linked traits
Definition
color blindness
Term
Gene
Definition
Instruction for building protein, determine specific traits
Term
gamete
Definition
one gene of each pair (Gh)
Term
Segregation
Definition
Pairs of alleles separated during gamete formation
Term
Diploid cell
Definition
homologeous pairs of chomosomes, one from each parent (46 chromosomes)
Term
Somatic
Definition
All living cells minus sex chromosomes
Term
Gene
Definition
Segment of DNA in a chromosome (Codes for protein)
Term
Centrosome
Definition
centrioles plus proteins
Term
Spermatogenesis
Definition
1 cell to 4 sperms
Term
Crossing over
Definition
Occurs in prophase 1 of meiosis, homologous chromosome cross dna alleles with eachother between X and Y. Sorts genes into gametes
Term
Sex-limited
Definition
M/F inherit same gene, only the genes appropriate for the persons gender are turned on. Ex: guys beard and girls breasts
Term
Interphase
Definition
G1: Cell growth
S: synthesis/DNA replication
G2: Organelles divide, preparation for mitosis
Term
Mitosis
Definition
Chromosomes sort into two sets and the cytoplasm divides, one copy of each chromosome into two cells
Term
Prophase
Definition
chromatin condense into chromosome, centrosome's move towards poles, nuclear membrane fragments and nucleolus disappears
Term
Translation to metaphase
Definition
nuclear envelope is gone, spindle microtubules attach to chromosomes at centrioles
Term
Metaphase
Definition
Duplicated chromosomes align midway between poles of the cell (equator)
Term
Anaphase
Definition
Sister chromatid splits, pulled towards pole region, spindles elongate (Opposite poles)
Term
Telephase "Reverse prophase"
Definition
Chromosome's are threadlike, nuclear envelope forms around each cluster, chromosomes de-condense into chromatin
Term
Cytokinesis
Definition
Division of cytoplasm, begins towards end anaphase; Cleavage furrow (plasma membrane is pulled around cell and pinched to make two cells)
Term
Parent cell contains 28 chromosomes and undergoes mitosis and cytokinesis the one daughter cell will contain how many chromosomes?
Definition
28
Term
28 parent cells unergo mitosis and cytokinesis then ____ daughter cells will be produced
Definition
56
Term
Meiosis
Definition
two consecutive division of the chromosomes.2N to n for reproduction
Term
Intephase (meiosis)
Definition
Germ cell copies DNA
Term
Meiosis I
Definition
Separation of homolegous chromosomes
Term
Meiosis II
Definition
Separation of sister chromatid NO REPLICATION OR INTERPHASE
Term
Crossing over
Definition
Homologous chromosomes pair up and break at the same place, exchange of segments of DNA
Term
Prophase 1
Definition
homologous chromosome condense, pair up, and swap segments, nuclear envelope breaks
Term
Metaphase 1
Definition
Homologous pairs align midway between spindle fibers
Term
Anaphase 1
Definition
Homologous chromosomes separate and begin heading towards the spindle poles
Term
Telaphase 1
Definition
two clusters of chromosomes reach the spindle poles, new nuclear envelope forms so two haploid
Term
Prophase II
Definition
chromosomes condense, nuclear envelope gone
Term
Metaphase II
Definition
Still duplicated chromosomes are aligned midway between spindles
Term
Anaphase II
Definition
Sister chromatids separate, unduplicated chromosomes head to spindle poles. DISJUNCTION
Term
Telaphase II
Definition
Cluster of chromosomes reach each spindle pole, nucleaer envelope encloses to form 4 haploid cells
Term
If a parent cell contains 28 chromosomes and undergo meiosis I and II then one daughter cell will contain....?
Definition
14
Term
If 28 parent cells undergo meiosis I and II then _____ daughter cells will be produced
Definition
112 ( 1 in 4 out)
Term
Two types of gamatogenesis
Definition
Spermatogenesis and Oogenesis
Term
Fusion of egg and sperm?
Definition
conception
Term
histology
Definition
study of tissues
Term
Four types of tissue
Definition
Epithelium, connective, muscle, nervous
Term
Epithelial
Definition
Location: Outer surface of skin, small intestines
Main function: protection
Term
Simple squamous
Definition
External surface of lungs and heart, passive transport of fluids/gas
Term
Simple Columnar
Definition
Location: Lines most digestive organs and small intestine
Function: Absorbs nutrients and produces mucus
Term
Stratified Squamous
Definition
Location: Skin, mouth, throat
Function: Protects against abrasion, drying out and infection
Term
Psuedostratified columnar
Definition
Location: Throat, nose, trachea
Function: Sweep mucus and fluid across tissue surface
Contains CILIA
Term
Transitional Epithelium
Definition
Location: Urinary bladder
Function: Allows for change in volume
Term
Microvilli
Definition
Location: Simple Columnar
Purpose: Increase the surface area
Term
Soft Connective Loose
Definition
Location: Tendons and ligaments
Function: Strength and elasticity
Term
Dense connective
Definition
Location: Surrounds blood vessels and nerves
Function: Elasticity and diffusion
Term
Compact Bone:
Definition
Location: Bone Shafts, outer ends of bone
Function: Protection
Term
Adipose
Definition
Fat tissue, under skin, around heart
Function: Energy reserve and insulation
Term
Blood
Definition
Found in bones of skeleton
Movement and support
Term
Hyaline Cartilage
Definition
Location: Ends of bones
Function: Reduces friction
Term
Smooth muscle
Definition
Location: walls of blood vessels, bladder, digestive tract
Function: On going contractions in the stomach and digestion
Involuntary/non-striated
Term
Skeletal Muscle
Definition
Location: Muscles
Function: Movement/maintain posture
Volunarty/Striated
Term
Cardiac Muscle
Definition
Location: Heart muscles
Function: Pumps blood
Involuntary/striated
Term
which connective tissues responsible to maintain Matrix?
Definition
Bone
Term
Which two connective have the Lacunae?
Definition
Hole where chondrocyte (which maintains matrix) lives
Location: Bone and cartilage
Term
Osteon
Definition
(Haversian systems) form the basic structural unit of bone, contains nerve and blood supply
Term
Leukocyte (granulated/nongranulated)
Definition
white blood cell
Granular: digest pathogens, basophil or neutrophil
Nongranular: immune response, lymphocyte or monocyte
Term
Intercalated Disks
Definition
in cardiac muscle and allows faster transmission
Term
Two functions of nervous tissue
Definition
Conduct electrical impulses
Response to stimuli
Term
name of functional unit of nervous tissue?
Definition
Neurons
Term
Part of neuron that receives?
Definition
Dendrites
Term
Part of neuron that transmits?
Definition
Axon
Term
Which cell supports the neuron?
Definition
Glial
Term
Light microscope
Definition
dissecting, good for large molecules
Term
Scanning Electron Microscope
Definition
makes objects 3-D, fine structures
Term
Transmission Electron Microscope
Definition
Great detail, uses no light but electron vaccum
Term
Accuracy
Definition
True Value
Term
Precision
Definition
same measurement multiple times
Term
1 inch
Definition
25.4 mm
Term
1 mL
Definition
1 cm3
Term
1 oz
Definition
28.35 g
Term
1 mL h20
Definition
1 g h20=1g/mL
Term
C
Definition
F-32/1.8
Term
centi
Definition
1x10-2
Term
milli
Definition
1x10-3
Term
micro
Definition
1x10-6
Term
nano
Definition
1x10-9
Term
pico
Definition
1x10-12
Term
R2 Value?
Definition
how well data fits the line, the closer to one the better
Term
volume
Definition
LxWxH
Term
2 parts of cell theory
Definition
smallest unit of life
all cells come from other cells
Term
plasma membrane
Definition
phospholipid bilayer
Term
Glycerol
Definition
backbone
Term
2 fatty acids
Definition
hyprophobic
"tails"
Term
phosphate
Definition
"head" PO4-
hydrophilic
Term
mitrochondria
Definition
powerhouse
Term
centrioles
Definition
organize microtubules
Term
plasma membrane
Definition
how substances move in/out of cell
Term
nucleus
Definition
keeps DNA safe
nuclear envelope
nucleolus
DNA in cytoplasm
Term
Ribosome
Definition
site of protein synthesis
Term
Rough ER
Definition
modifies new polypeptide bond
Term
Smooth ER
Definition
Makes lipids/inactivates toxins
Term
Diffusion
Definition
passive
down concentration gradient
small/nonpolar
Term
osmosis
Definition
h20 movement
due to tonicity
Term
Selective pathway
Definition
facilitated diffusion
active transport
Term
facilitated diffusion
Definition
high concentration to low concentration
enter/leave cell through channel
Term
active transport
Definition
against concentration gradient
uses ATP
Term
Tonicity
Definition
Deals with concentration
Term
Isotonic
Definition
equal concentration
Term
hypotonic
Definition
larger concentration inside cell than outside of cell.
If a cell is placed into a hypotonic solution, the water will flow into the cell causing it to swell and possibly lyse
Term
hypertonic
Definition
larger concentration outside cell than inside cell
If a cell is placed into a hypertonic solution, the water will flow out of the cell causing it to crenate
Term
Crenation
Definition
hypertonic
shrivels
Term
hemolysis
Definition
hypotonic
swells and explodes
Term
glucose
Definition
benedicts
pos: yellow
neg: no change
Term
Starch
Definition
Potassium Iodide
pos: black
neg: no change
Term
NaCl
Definition
silver nitrate
pos: cloudy
neg: no change
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