Term
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Definition
plasma
buffy coat
hematocrit |
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Term
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Definition
cell of immune system
macrophages
platelet |
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Term
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Definition
cell fragments
blood clotting factors
come from megakaryote |
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Term
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Definition
| DIC- desimthated Intravascular Coagulation |
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Term
| which stage ejects the mitochondria and nucleus |
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Definition
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Term
| what surrounds the erythrocyte |
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Definition
epithelium aveolus
endothelium
transmembrane proteins ; glycoproteins |
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Term
| What makes up a hemoglobin |
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Definition
four globular chains
2 alpha chains
2 beta chains
iron molecule |
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Term
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Definition
| N ring around iron, makes it bindable with Oxygen |
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Term
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Definition
Splenic Artery
Splenic Vein
Capillaries
red pulp
white pulp |
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Term
| Macrophage VS. erythrocyte |
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Definition
Macrophaes endocytosis worn out erythrocyte, using transmembrae proteins
digest it, recycle the FE in the liver |
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Term
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Definition
Glutamic acid affects folding… valine
when modded, macros eat them up more, shorter life span
good= anti malaria, bad = sickle cell/mishapen |
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Term
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Definition
signals in kidney responding to low O2 levels
stimulate proethryocyte- increase devision |
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Term
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Definition
spleen
tonsils, Peyers Patch
thymus
Lymph (nodes) |
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Term
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Definition
aggregation of immune system cells
leukocytes germinal region
monitor for bacterial infections in blood, Attack |
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Term
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Definition
on the gut, patches along the gi tract
monitors for pathogens
germinal regions where cells of the immune system
bacteria in the epithelium crypts
protein shed by bacterie travel through m cells, exposed to leukocytes |
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Term
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Definition
selecting a group of cells called t-lymphocytes for potency and specificity
need to recognize self vs. non-self
nurse cells
go wrong= MS, AIDs, Chromes |
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Term
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Definition
monitors interstatial/extracellular fluid from most of the body
osmotic and hydrostatic pressure (more!) pushes water out from capillaries |
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Term
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Definition
collection of immunity cells in germinal regions
t/b-lymphochytes |
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Term
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Definition
empty into ducts, into trucks, into subclavian veings
lymph passes through lymph nodes |
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Term
| Granulocytes expell what? |
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Definition
| bleach, h20, free electrons |
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Term
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Definition
recognizing sequence of Amino acids
memroy: respond to reentry of pathogen
slow: 10 day to 2 weeks to develop |
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Term
| Cellular branch of Specific |
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Definition
T help, T killer
antibody of these cells is always a transmembrane protein= t cell receptors |
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Term
| Humoral branch of specific |
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Definition
release antibodies via exocytosis
secreted antibodies |
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Term
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Definition
| self proteins that bind to nonself proteins called antigens |
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Term
| Macrophage specific response |
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Definition
antigen presenting cell
finds a pathogen and takes it through the system
presents part of the pathogen to immunity system cell |
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Term
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Definition
redness= dialation of blood cells from histines
swelling= opening gap juction
warmth= dialation of blood cells from histines
pain |
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Term
| Response to bacteria/inflammation |
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Definition
bacteria in the dermis
fibrocytes activate release of neutrophils in red bone marrow into vasculature
back to dermin to release h20 bleach and e- |
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Term
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Definition
activated by pathogens
non specific
granulocytes |
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Term
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Definition
activated by cyokines
release histamine
targets endothelia cells and vascular/smooth muscle |
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Term
| Viral infection of epithelial cells |
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Definition
virus with a hemogluten bind to receptor= endocytosis
goes to nucles of the cell
cell releases interfereon to warn others |
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Term
| Consequences of interferon |
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Definition
| slow down endocytosis, rna transcription, protein synthesis |
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Term
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Definition
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Term
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Definition
| masking active sites on antigen |
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Term
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Definition
binds to cell binding portion of the toxin
purfied antibodies made in other animals to make antivenom
preciptation of proteins=ump together for macrophages |
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Term
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Definition
compliment fixation, is innate and specific
compliment binding site on antibody |
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Term
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Definition
| antigen+antibody=division |
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Term
| Following the antigen through the naïve b lymphocyte |
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Definition
binding, endocytosis,
lysosome where hyrolytic enzymes digest protein into fragments
move to endosome and attached to an MHC protein |
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Term
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Definition
| "antibody" of the cellular branch |
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Term
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Definition
CD4 binds to MHC II and the protein binds to protein
releases Interleukins from T cell, binds to interlukin b cell receptor |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| structure of cardiomycocytes |
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Definition
striated muscle z lines
uninucleate nucleus
intercalated disk |
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Term
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Definition
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Term
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Definition
| anchoring junctions, desosomes |
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Term
| conductile cardiomyocytes |
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Definition
pacemaker cells
deliver posirive charge |
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Term
| conductile cardiomyocytes: channel type |
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Definition
unique
CA
K
HCN- hyperpolarizing cyclic nucleotide |
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Term
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Definition
increase ramp potential = increase heart
increased by binding cyclic amp |
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Term
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Definition
binding cyclic amp
innflux of sodium
changing membrane potential, hyperpolarized as opens more channels |
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Term
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Definition
sinoatrial node
atrioventricle node
linked by gap junction |
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Term
| sympathetic branch of auto CN |
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Definition
| Releases norepinephrine, increase cyclic amp, increases heart rate AP |
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Term
| parasympathetic and heart |
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Definition
effects to slow heart rate
restricted to pacemaker cells
increased potassium permability, making ramp potential more difficult |
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Term
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Definition
pressure change = resistance X flow
decrese resistance, increase flow |
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Term
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Definition
r to the fourth
if you double radius, you increase flow x16 |
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Term
| innervation from sympathetic on veins |
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Definition
contraction of smooth muscles
increased pressure and resistance |
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