Term
| How many subunits does hemoglobin have? |
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Definition
| 4, is a tetramer of alpha(2)beta(2) |
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Term
| What is the general structure of myoglobin? |
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Definition
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Term
| Why is an oxygen transporter even necessary? |
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Definition
| because the solubility of oxygen within blood plasma 10^-4 M is too low |
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Term
| What is the solubility of oxygen that contains hemoglobin? |
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Definition
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Term
| What are other examples of molecules other hemoglobin that carry oxygen? |
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Definition
| hemocyanin and hemerythrin (doesn't use iron) |
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Term
| How do fish that live in the bottom of the ocean survive without hemoglobin? |
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Definition
| low temperature increases solubility, therefore there is no need for an oxygen carrier |
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Term
| how many heme molecules are in a hemoglobin molecule? |
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Definition
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Term
| how many heme molecules does myoglobin have? |
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Definition
|
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Term
| what other molecules is heme found in other than hemoglobin and myoglobin ? |
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Definition
-catalase
-peroxidase
-cytochromes
-cytochrome P450 |
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Term
| How many pyrrole rings are attached to heme? |
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Definition
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Term
| How does the conformation of histidine in heme help oxygen bind? |
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Definition
| by histidine being in the open 6th axial position, it allows O2 to bind |
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Term
| what is heme without the iron? |
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Definition
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Term
| What is hemoglobin and myoglobin called when the iron is oxidized from Fe(II) to Fe(III)? |
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Definition
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Term
| What is the enzyme that reduces Fe(III) back to Fe(II)? |
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Definition
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Term
| nitric oxide is an example of what? |
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Definition
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Term
| How does nitric oxide couple with MbO2? |
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Definition
NO + MbO2 ==> NO3- + MetMb
Once NO has delivered a message, it needs to be removed. Myoglobin helps remove it. |
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