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Details

Blood Disorders
Clin Med test 1
20
Medical
Graduate
01/03/2010

Additional Medical Flashcards

 


 

Cards

Term
Hematocrit less than 41% (hemoglobin <13.5 g/dL in males and 37% (hemoglobin <12 g/dL in females).
Definition
Anemia
Term
Almost always due to either megablastic anemia or myelodysplasia (MVC > 125 fL)
Definition
Severe macrocytic anemia
Term
Serum ferritin < 12 mcg/L.  Caused by bleeding unless proven otherwise. Responds to iron therapy.
Definition
Iron Deficiency Anemia
Term
Absorbtion occurs in the stomach, duodenum and upper jejunum.
Definition
Iron absorption
Term
The most important cause of iron deficiency.
Definition
Blood loss
Term
Easily fatigued, tachycardia, palpitations and tachypnea on exertion.
Definition
Symptoms of iron deficient anemia
Term
A ferritin value of less than 12 mcg/L
Definition
High indicator of of iron deficiency
Term
Ferrous sulfate, 325 mg three times a day.
Definition
The preferred therapy for iron deficient anemia.
Term

Anemia, normocytic, or microcytic.

Normal or increased iron stores.

Underlying chronic disease.

Definition
Anemia of chronic disease
Term
Chronic infection, inflammation, cancer and liver disease.
Definition
Common causes associated with mild or moderate anemia.
Term

T/F

Patients undergoing hemodialysis regularly lose both iron and folate during dialysis.

Definition
True
Term
Hematocrit rarely falls below 60%, MVC is usually normal or slightly reduced.
Definition
Lab finding for anemai of chronic disease
Term
What is the treatment for anemia from renal failure and other secondary anemias?
Definition
Purified recombinant erythopoietin (epoetin alfa)
Term
What is the treatment for anemia of chronic disease?
Definition
In most cases, no treatment is necessary.
Term

Microcytosis out of proportion to the degree of anemia, pos. family history or lifelong personal hx of microcytic anemia, abnormal red blood cell morphology with microcytes, and target cells.

 

Definition
Thalassemias
Term
Hereditary disorders  characterized by reduction in the synthesis of globin chains (alpha and beta).
Definition
Thalassemias
Term
Seen primarly in person from southeast Asia and China, and less commonly in blacks.
Definition

 

Alpha Thalassemia

Term
Primarly affects person of Mediterranean origin (Italian, Greek) and to a lesser extent Chinese and other Asians, and blacks.
Definition
Beta Thalassemia
Term
Two alpha globin genes, hematocrit between 28% and 40%, MCV is low (60-75 fL), RBC is normal or increased.  Peripheral blood smear shows microcytes, hypochromia, occasional target cells, and acanthocytes.  Reticulocyte count and iron parameters are normal.
Definition
Alpha Thalassemia trait
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