Term
| Blood coagulation prototypes |
|
Definition
| Injectable Heparin Sodium/Oral Warfarin (coumadin) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| What class does heparin belong to? |
|
Definition
| Injectable anticoagulants |
|
|
Term
| Where is heparin NOT absorbed? |
|
Definition
|
|
Term
| Is heparin rapid or slow action |
|
Definition
|
|
Term
|
Definition
|
|
Term
| What is heparin's half life |
|
Definition
|
|
Term
| Where is heparin endogenous? (where it grows or is produced by) |
|
Definition
|
|
Term
|
Definition
| Inactivates anti-thrombin so factor X is neutralized |
|
|
Term
| Heparin High dose effects |
|
Definition
| Inactivates thrombin and prevents conversion of fibrinogen to fibrin. Basically interferes with steps in coagulation pathways.DOES NOT DISSOLVE CLOTS |
|
|
Term
| How do we monitor heparin? |
|
Definition
| PTT (partial thromboplastin time) or aPTT. (aPTT is more sensitive) |
|
|
Term
|
Definition
| Prophylaxis for thrombosis or embolism. ( tx for thrombosis, embolism |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Where is Coumadin absorbed well? |
|
Definition
|
|
Term
| Is Coumadin action slow or rapid? |
|
Definition
|
|
Term
| Why do we overlap Coumadin with heparin |
|
Definition
| to get a continued anticoagulant effect |
|
|
Term
|
Definition
| Inhibits the synthesis of active Vitamin K dependent clotting factors X, IX, and VII. DOES NOT DISSOLVE CLOTS |
|
|
Term
| Coumadin Therapeutic range |
|
Definition
| INR of 2-3. May want 2.5-3.5 with active embolism |
|
|
Term
| How long does Coumadin take to be effective? |
|
Definition
|
|
Term
| How do we monitor Coumadin? |
|
Definition
| By INR and PT (prothrombin time) |
|
|
Term
|
Definition
| Prophylaxis treatment for thrombosis or embolism. Adjunctive for acute MI, chronic atrial fibrillation |
|
|
Term
| Side effects of all anti-coagulants (oral and injectable) |
|
Definition
| Excessive GI bleeding, gums, nose, intracranial, petechiae, IV sites or wounds |
|
|
Term
|
Definition
| Allergy Response, osteoporosis |
|
|
Term
|
Definition
| Diarrhea, hepatitis, leukopenia |
|
|
Term
| Contraindications in ALL anticoagulants |
|
Definition
| Bleeding, peptic ulcer, HYPERTENSION, recent hemorrhagic stroke, hypersensitivity |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Where is a heparin injection usually given? How do you do it? |
|
Definition
| Abdomen, don't aspirate, don't rub, hold for 10 seconds |
|
|
Term
|
Definition
| on pump, hold for 5 min if d/c. Monitor bleeding. Pressure on sites |
|
|
Term
| Coumadin patient teaching |
|
Definition
| Where a medic alert bracelet at all times. Teach many drug interactions, teach food interactions (green leafies) |
|
|
