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Women's & Gender Studies
12th Grade
01/29/2013

Additional Women's & Gender Studies Flashcards

 


 

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Term
“slapped cheek” rash
Definition
Parvovirus B19/Erythrovirus
Term
Dome-shaped papule with “central dimple”
Definition
Molluscum contagiosum (DNA poxvirus)
Term
Pustule with honey-colored crust
Definition
Impetigo
Term
Panton-Valentine Leukocidin
Definition
CA-MRSA
Term
Rash with centripetal spread
Definition
Rocky Mountain Spotted Fever (Rickettsia rickettsii)
Term
Rash with centrifugal spread
Definition
Typhus (R. prowazekii, R. typhi, Orienta tsutsugamushi)
Term
Hutchinson’s teeth
Definition
Congenital syphilis
Term
Donovan bodies
Definition
Klebsiella granulomatous
Term
Painful genital ulcer (2)
Definition
H. ducreyi, HSV
Term
Painless genital ulcer (3)
Definition
T. pallidum, C. trachomatis (L1-L3), K. granulomatis
Term
P fimbriae
Definition
UTI E. coli (especially in pyelonephritis)
Term
“currant jelly” sputum
Definition
Klebsiella pneumonia
Term
Bipolar staining (“safety pin”)
Definition
Yersinia, Francisella
Term
“Bulls eye” rash
Definition
Borrelia burgdorferi (Lyme Disease), Erythema migrans
Term
Targetoid lesions (usually multiple)
Definition
Erythema multiforme
Term
Drug rxn: severe frontal headache
Definition
Indomethacin (15-25% of patients)
Term
Sign of Leser-Trelat
Definition
(sudden occurrence of multiple seborrheic keratosis) indicates paraneoplastic syndrome
Term
Papule with “stuck on” appearance
Definition
Seborrheic keratosis
Term
Velvety, thickened skin
Definition
Acanthosis nigricans
Term
Peripheral palisading
Definition
Basal cell carcinoma
Term
“mask of pregnancy”
Definition
Melasma
Term
ABCDE’s
Definition
Malignant Melanoma (asymmetry, borders, color, diameter, evolution)
Term
Firm papule with “dimple sign” when squeezed
Definition
Benign Fibrous Histiocytoma/Dermatofibroma
Term
Pautrier’s microabscess
Definition
Mycosis Fungoides
Term
Sezary-Lutzner cell
Definition
(cerebriform nuclei) Mycosis Fungoides
Term
Auspitz sign
Definition
Psoriasis
Term
Red plaques with silvery scale
Definition
Psoriasis
Term
Malar rash
Definition
Lupus
Term
Pruritic, purple, polygonal papules
Definition
Lichen Planus
Term
Civatte/colloid bodies
Definition
(necrotic keratinocytes in the dermis) Lichen Planus
Term
Abs against desmoglein 3
Definition
Pemphigus vulgaris
Term
“tombstone” basal layer
Definition
Pemphigus vulgaris
Term
IgA in tips of dermal papillae
Definition
Dermatitis Herpetiformis (associated with Celiac disease)
Term
HPV 16, 18, 33
Definition
SqCC
Term
HPV 6, 11
Definition
Benign genital wart (condyloma acuminatum)
Term
Koilocytes
Definition
(haloed keratinocytes in s. granulosum) HPV
Term
Auer rods
Definition
Myeloblasts (AML; high grade myelodysplastic syndrome)
Term
>20% myeloblasts
Definition
AML
Term
MPO positive (myeloperoxidase)
Definition
AML—neutrophilic
Term
SBB positive (Sudan black B)
Definition
AML—neutrophilic
Term
NSE positive (Nonspecific esterase)
Definition
AML—monocytic
Term
t (8;21)
Definition
AML with good prognosis
Term
t (15;17)
Definition
AML promyelocytic type (all trans-retinoic acid treatment)
Term
inv (16)
Definition
AML with good prognosis
Term
>25% blasts in marrow
Definition
ALL
Term
TdT positive
Definition
Immature T- or B-cells
Term
t (9;22)
Definition
bcr-abl, Philadelphia chromosome, CML*, ALL, AML - *required for diagnosis
Term
“soccer ball” or “cracked earth” nuclei
Definition
CLL
Term
ZAP-70 positive
Definition
Unmutated CLL (poorer prognosis)
Term
Richter syndrome
Definition
CLL à diffuse large B-cell lymphoma
Term
TRAP positive
Definition
Hairy cell leukemia
Term
Hypercellular bone marrow + peripheral cytopenia
Definition
Myelodysplastic syndrome
Term
Plethora + intense pruritis after bathing
Definition
PV
Term
Erythromelalgia
Definition
(throbbing/burning of hands and feet) essential thrombocytosis
Term
“B” symptoms: fever, loss of appetite, weight loss
Definition
Lymphoma
Term
Reed-Sternberg cells
Definition
Hodgkin Lymphoma
Term
t (14;18)
Definition
Bcl-2, Follicular lymphoma (& DLBCL)
Term
t (11;14)
Definition
cyclin D1, Mantle cell lymphoma
Term
Mass of jaw/facial bone
Definition
Endemic Burkitt’s Lymphoma (EBV-associated)
Term
“starry sky” morphology
Definition
Burkitt’s lymphoma
Term
t (8;14)
Definition
c-MYC, Burkitt’s lymphoma
Term
Lacunar type RS cell + collagen bands
Definition
Nodular Sclerosis Hodgkin Lymphoma
Term
Cancers with bone pain
Definition
MM, ALL
Term
RBC rouleaux
Definition
MM (and other things)
Term
Bence-Jones proteinuria
Definition
MM
Term
“punched out” lesions in bone
Definition
MM
Term
Hyperviscosity syndrome; Waldenstrom macroglobulinemia
Definition
Lymphoplasmacytic Lymphoma, over secretion of IgM
Term
>20% plasma cells on WBC differential
Definition
Plasma cell leukemia
Term
Effacement of podocytes only
Definition
MCD
Term
Effacement of podocytes + focal detachment of epithelial cell
Definition
FSGS
Term
Diffuse capillary membrane thickening + spikes/domes
Definition
Membranous glomerulonephritis/ glomerulopathy/ nephrits/ idk why this has so many names
Term
Subendothelial and mesangial immune complexes
Definition
Membranoproliferative glomerulonephritis type I
Term
Ribbon-like deposits on EM, Subepithelial humps, “lumpy bumpy” IF
Definition
(immune complexes in bm) Membranoproliferative glomerulonephritis type II, (immune complexes above the bm) Acute proliferative glomerulonephritis, Acute proliferative glomerulonephritis, (and, according to our notes, RPGN II)
Term
Anti-GBM antibody
Definition
Goodpasture’s syndrome, RPGN type I
Term
Crescent formation in glomeruli
Definition
RPGN
Term
ANCA-associated glomerulonephritis
Definition
RPGN Type III
Term
Mesangial IgA deposits
Definition
IgA Nephropathy (Berger disease), HSP
Term
Diffuse thinning of glomerular bm
Definition
Thin basement membrane disease (benign familial hematuria)
Term
Defect in alpha-5 chain of type-4 collagen
Definition
Alport’s disease (X-linked), autosomal forms involve alpha 3 and 4 as wel
Term
Splitting of glomerular bm
Definition
MPGN Type I, alport's disease
Term
Lamination of lamina densa
Definition
Alport’s disease
Term
Adult type PKD
Definition
Autosomal dominant, polycystin genes (PKD1 and PDK2)
Term
Childhood PKD
Definition
Autosomal recessive Fibrocystin gene (PKHD1)
Term
Cysts at corticomedullary junction
Definition
Familial Nephronophthisis (Medullary cystic disease complex)
Term
Michaelis-Gutmann bodies
Definition
(bacteria, Ca, and Mg—degradation products) Malacoplakia
Term
HCG production
Definition
Syncytiotrophoblasts present in tumor
Term
Testicular tumor positive for AFP +/- A1AT
Definition
Yolk Sac tumor
Term
Crystalloids or Reinke
Definition
Leydig cell tumor
Term
Testicular mass + hormonal change (gynecomastia; sexual precosity in kids)
Definition
Leydig cell tumor
Term
PSA
Definition
Organ-specific but NOT cancer-specific
Term
Sezary-Lutzner cell
Definition
Mycosis fungoides
Term
Uniform acanthosis with confluent parakeratosis
Definition
Psoriasis
Term
Auspitz sign (pinpoint bleeding)
Definition
Psoriasis
Term
Salmon-pink plaques
Definition
Psoriasis
Term
Monro's microabscesses
Definition
Psoriasis
Term
Spongiform pustules of Kogoj
Definition
Psoriasis
Term
Civatte/colloid bodies
Definition
Lichen Planus
Term
Saw tooth basal layer
Definition
Lichen Planus
Term
IgG against desmoglein 3
Definition
Pemphigus Vulgaris -
Term
Nikolsky's sign -
Definition
Pemphigus Vulgaris -
Term
tombstone basal layer
Definition
Pemphigus Vulgaris -
Term
IgG antibodies against hemidesmosome proteins
Definition
Bullous Pemphigoid
Term
anti-basement membrane
Definition
Celicas/ Dermatitis Herpetiformis
Term
honey-colored crust
Definition
Impetigo
Term
Psuedo-horn cysts
Definition
Seborrheic keratosis
Term
Sign of Leser-Trelat
Definition
Explosive Seborrheic keratosis, normally indicating adenocarcinoma
Term
Squamous pearls
Definition
Squamous cell carcinoma
Term
"Rodent Ulcer"
Definition
Basal Cell Carcinoma
Term
retraction artifact
Definition
Basal Cell Carcinoma
Term
Peripheral Palisading
Definition
Basal Cell Carcinoma
Term
"Gorlin syndrome"
Definition
Basal Cell Carcinoma
Term
Nevoid basal cell carcinoma syndrome
Definition
Basal Cell Carcinoma
Term
PTCH gene on chromosome 9q22.3l
Definition
Nevoid basal cell carcinoma syndrome
Term
Sonic Hedge Hog (SHH) gene product mutation
Definition
Nevoid basal cell carcinoma syndrome
Term
Medullo blastomas, ovarian fibromas, odontogenic keratocysts, intracranial calficiations, rib abnormalities, palmar/plantar pits
Definition
Nevoid basal cell carcinoma syndrome
Term
Smoothened activation
Definition
Nevoid basal cell carcinoma syndrome
Term
Cup-shaped squamous proliferation and keratin plug
Definition
Keratoacanthoma
Term
cup-shaped tumor filled with keratin debris
Definition
Keratoacanthoma
Term
"Mask of Pregnancy"
Definition
Melasma
Term
elongation of rete pegs
Definition
Lentigo
Term
Melanocyte nests
Definition
Nevi
Term
Bridging of nests
Definition
Dysplastic nevus
Term
Melanoma in Asian and African American
Definition
Acral Lentiginous Melanoma
Term
Dimple Sign
Definition
Dermatofibroma/Benign Fibrous Histiocytoma (BFH)
Term
p16INK4A (CDNK2) mutations
Definition
Melanoma
Term
p14ARF mutations
Definition
Melanoma
Term
BRAF mutations
Definition
Melanoma
Term
NRAS mutations
Definition
Melanoma
Term
Epidermotropism
Definition
Mycosis fungoides
Term
Cerebriform nuclei
Definition
Sezary-Lutzner cell
Term
Prautrier's microabscesses
Definition
Mycosis fungoides
Term
Targetoid lesions
Definition
Erythema Multiforme
Term
Mucin deposited in dermis
Definition
Lupus
Term
Malar Rash
Definition
Lupus
Term
Koebner phneomenon
Definition
Vitiligo, Psoriasis, Lichen Planus
Term
Wickham striae
Definition
Lichen Planus
Term
Wedge-shaped hypergranulosis
Definition
Lichen Planus
Term
Civatte/colloid bodies
Definition
Lichen Planus
Term
Dermatitis Herpetiformis disease association
Definition
Celiacs
Term
Koilocytes
Definition
HPV infection
Term
Myeloblast count > 20%
Definition
Acute Myeloid Leukemia (AML)
Term
Auer rods
Definition
Acute Myeloid Leukemia
Term
CD2, CD5, CD7
Definition
T cell markers (seen in Precursor T-cell ALL/LBL)
Term
JAK 2 mutation
Definition
Polycythemia Vera, Essential Thrombocythemia (50%), Primary Myelofibrosis (PMF) (50-60%)
Term
Large megakaryocytes with highly lobulated nuclei
Definition
Essential Thrombocythemia (ET)
Term
WBC Toxic granulation, Dohle Body, Cytoplasmic vacuoles
Definition
Leukemoid Reaction (signs of fighting infection)
Term
Gingival hyperplasia (gum hypertrophy)
Definition
Monoblastic AML
Term
Myeloid sarcoma
Definition
AML
Term
earth or soccer ball nuclei
Definition
Chronic Lymphocytic Leukemia (CLL)
Term
Most common leukemia in the Western world
Definition
Chronic Lymphocytic Leukemia (CLL)
Term
fried egg cells
Definition
Hairy Cell Leukemia
Term
(+) CD19, CD20, 11c
Definition
Hairy Cell Leukemia
Term
Red cell lakes in spleen sinusoids
Definition
Hairy Cell Leukemia
Term
TRAP(+) lymphocyte cells (Tartrate Resistant Acid Phosphatase)
Definition
Hairy Cell Leukemia
Term
CD5, CD20 (+) - co-expression
Definition
Chronic Lymphocytic Leukemia
Term
↑ basophils in peripheral blood
Definition
CML
Term
teardrop shaped RBCs
Definition
Primary Myelofibrosis (PMF))
Term
Wickham striae (oral mucosa)
Definition
Lichen Planus
Term
Reed-Sternburg (RS) cells
Definition
Hodgkin Lymphoma
Term
Bence Jones proteins
Definition
Multiple Myeloma
Term
paraprotein
Definition
Multiple Myeloma
Term
KSHV/HHV8, and EBV viruses
Definition
Body cavity Diffuse large B cell lymphoma
Term
Jellyfish- like cells
Definition
Diffuse large B cell lymphoma
Term
cyclin D1
Definition
Mantle Cell Lymphoma
Term
starry sky pattern
Definition
Burkitt's Lymphoma
Term
c-MYC gene
Definition
Burkitt's Lymphoma
Term
lacunar type RS cells + collagen bands
Definition
Nodular Sclerosis Hodgkin Lymphoma
Term
"punched out" bone lesions
Definition
Multiple Myeloma
Term
(+) TdT in nucleus
Definition
Lymphoblast Stain (ALL)
Term
·       CD10, CD19, CD20
Definition
·       B- ALL (most common)
Term
·       range from CD2-CD8
Definition
·       T-ALL
Term
Myeloperoxidase (+)
Definition
Myeloblast stain (AML)
Term
Down Syndrome before the age of 5 (Leukemia association)
Definition
Acute Megakaryoblastic leukemia
Term
Down Syndrome afer the age of 5 (Leukemia association)
Definition
Acute Lymphoblastic Leukemia
Term
Smudge cells
Definition
Chronic Lymphocytic Leukemia
Term
"Owl-eyed nucleus"
Definition
Reed-Sternberg Cell (Hodkins Lymphoma)
Term
Endodermal Sinuses/ Schiller-Duval bodies
Definition
Yolk Sac Tumor (Endodermal Sinus Tumor)
Term
Eosinophilic hyaline globules containing AFP
Definition
Yolk Sac Tumor (Endodermal Sinus Tumor)
Term
crytaslloids of Reinke
Definition
Leydig Cell Tumor-
Term
Homogenous testicular mass with no hemorrhage or necrosis
Definition
Seminoma
Term
most common cancer in men
Definition
Prostate Adenocarcinoma
Term
spike and dome appearance on EM
Definition
Membranous Nephropathy
Term
"tram-track" appearance
Definition
Membranoproliferative Glomerulonephritis
Term
anti-C3 nephritic factor
Definition
Membranoproliferative Glomerulonephritis- Type II
Term
Kimmelstiel Wildson nodules
Definition
Nephrotic syndrome caused by DM
Term
Congo-Red staining with apple-green birefringence under polarized light
Definition
Systemic Amyloidosis = nephrotic syndrome
Term
crescents ( fibrin/macrophages) in Bowman's Space
Definition
Rapidly Progressive Nephritic Syndrome
Term
Cortical scarring and blunted calyces of kidney
Definition
Chronic Pyelonephritis
Term
Thyroidization of the kidney
Definition
Chronic Pyelonephritis
Term
staghorn calculi in renal calyces in adults
Definition
Ammonium Magnesium Phosphate Kidney Stone
Term
staghorn calculi in renal calyces in kids
Definition
Cysteine Kidney Stones
Term
Hematuria (Cola-colored)
Definition
Acute Proliferative (Poststreptococcal, Postinfection) Glomerulonephritis
Term
Michaelis-Gutmann bodies
Definition
Malacoplakia
Term
MCC of osteomyelitis
Definition
S.     Aureus
Term
Janeway lesions
Definition
Infectious endocarditis (think S. aureus!)
Term
Most common cause of all fungal infections
Definition
Candida
Term
"Rose Handler's Disease"
Definition
Sporotrichoisis - caused by Sporothrix schenckii
Term
noncancerous laryngeal papillomas
Definition
Recurrent Respiratory Papillomatosis
Term
HPV 6 or 11
Definition
Recurrent Respiratory Papillomatosis
Term
HPV 16 or 18
Definition
Cervical Cancer
Term
Reactive JC polyoma:
Definition
progressive multifocal leukoencephalopathy
Term
fever and "slapped face"
Definition
erythema infectiousum (erythrovirus/parvovirus B19)
Term
globoside (group P antigen)
Definition
erythrovirus/parvovirus B19
Term
Adeno-associated virus
Definition
parvovirus
Term
"bulls-eye" skin rash
Definition
Lyme Disease
Term
Donovian bodies
Definition
Granuloma inguinale (Donovanosis)
Term
"swimming pool granulomas"
Definition
Mycobacterium marinum- slow growing/atypical
Term
The only extracellular Mycobacterium
Definition
Mycobacteria ulcerans
Term
Mycolactone production
Definition
Mycobacteria ulcerans
Term
Buruli ulcer disease
Definition
Mycobacteria ulcerans
Term
Loss of temperature sensitivity & (+) lepromin skin test
Definition
Tuberculoid leprosy (M. leprae)
Term
Most common Rickettsial infection
Definition
Rickettsial rickettsii- Rocky Mountain Spotted Fever (RMSF)
Term
Severe frontal Headache & centripetal rash
Definition
Rickettsial rickettsii- Rocky Mountain Spotted Fever (RMSF)
Term
trunk to extremities (centrifugal) rash
Definition
Typhus
Term
localized esher at bite site and centrifugal rash
Definition
Orientia tsutsugamushi - Scrub Thyphus
Term
co-transmitted w/ Lyme Disease
Definition
Human granulocytotrophic anaplasmosis (HGA) - Anaplasma phagocytophlilum
Term
black-legged deer ticks
Definition
Human granulocytotrophic anaplasmosis (HGA) - Anaplasma phagocytophlilum
Term
black-legged deer ticks
Definition
Borrelia burgdorferi- Lyme disease
Term
Lone star tick
Definition
Human ewingii erlichiosis (HEE) - Ehrlichia eqingii
Term
distinctive bone pain (shins)
Definition
Bartonella quintana- Trench Fever
Term
AIDs pt w/ Bacillary peliosis hepatitis
Definition
Bartonella henselae - Cat Scratch Disease
Term
Weil's disease
Definition
Leptospira interrogans: Leptospirosis
Term
Saddle nose
Definition
Treponema pallidum - Syphilis
Term
Hutinson's teeth
Definition
Treponema pallidum - Syphilis
Term
Jarish-Herxheimer reaction following Penicillin
Definition
Treponema pallidum - Syphilis
Term
Arthritis/Tenosynovitis & Dermatitis
Definition
Gonorrhea
Term
Most common sexually transmitted pathogen
Definition
C. trachomatis servars D-K:
Term
large mucoid capsule = virulence factor
Definition
Klebsilla pneuomiae
Term
"currant jelly sputum"
Definition
Pneumonia: Klebsilla pneuomiae
Term
Urease (+) organism causing kidney stones
Definition
Proteus
Term
contaminated dry powdered infant formula
Definition
Enterobacter sakazakii (cronobacter)
Term
UTI with swarming motility on agar surface
Definition
Proteus
Term
owl's eye cell
Definition
CMV
Term
Bipolar staining with safety pin appearance
Definition
Yersinia
Term
Bubo
Definition
Yersinia pestis- The Plague
Term
Fra1 antibody
Definition
Yersinia pestis
Term
enhanced by erythritol
Definition
Brucella abortus
Term
lung infiltrate, liver involvement, animal exposure
Definition
Brucella
Term
minute granulomas
Definition
Brucella
Term
milker's nodes
Definition
Parapoxvirus
Term
"rabbit fever"
Definition
Francisella tularensis (Tularemia)
Term
"child-bed fever"
Definition
Puerperal sepsis (S. pyogenes)
Term
Muriform cells/Medlar bodies
Definition
Chromoblastomycosis
Term
thick-walled, dark brown rounded sclerotic cells
Definition
Chromoblastomycosis
Term
planar splitting division
Definition
Chromoblastomycosis
Term
lesions that resemble cauliflower
Definition
Chromoblastomycosis
Term
mycelial lesions of the tissue
Definition
Phaeohyphomycosis
Term
contaminated epidural steroid injections
Definition
Phaeohyphomycosis
Term
Madura foot
Definition
Mycetoma
Term
Pus with white or black fungal granules/grains
Definition
Mycetoma
Term
keratinophilic fungi
Definition
Dermatophytes
Term
pteridine that fluoresces bright blue-green under long wave UV light (Wood Lamp)
Definition
Microsporum (Dermatophyte)
Term
extensive ground-glass changes
Definition
Pneumocystisi jiroveci pneumonia (PCP)
Term
MCC of morbidity & mortality or AIDs pts
Definition
Pneumocystisi jiroveci pneumonia (PCP)
Term
dewdrops on rose petals
Definition
Varicella-Zoster Virus
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