Term
|
Definition
| Parvovirus B19/Erythrovirus |
|
|
Term
| Dome-shaped papule with “central dimple” |
|
Definition
| Molluscum contagiosum (DNA poxvirus) |
|
|
Term
| Pustule with honey-colored crust |
|
Definition
|
|
Term
| Panton-Valentine Leukocidin |
|
Definition
|
|
Term
| Rash with centripetal spread |
|
Definition
| Rocky Mountain Spotted Fever (Rickettsia rickettsii) |
|
|
Term
| Rash with centrifugal spread |
|
Definition
| Typhus (R. prowazekii, R. typhi, Orienta tsutsugamushi) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Painful genital ulcer (2) |
|
Definition
|
|
Term
| Painless genital ulcer (3) |
|
Definition
| T. pallidum, C. trachomatis (L1-L3), K. granulomatis |
|
|
Term
|
Definition
| UTI E. coli (especially in pyelonephritis) |
|
|
Term
|
Definition
|
|
Term
| Bipolar staining (“safety pin”) |
|
Definition
|
|
Term
|
Definition
| Borrelia burgdorferi (Lyme Disease), Erythema migrans |
|
|
Term
| Targetoid lesions (usually multiple) |
|
Definition
|
|
Term
| Drug rxn: severe frontal headache |
|
Definition
| Indomethacin (15-25% of patients) |
|
|
Term
|
Definition
| (sudden occurrence of multiple seborrheic keratosis) indicates paraneoplastic syndrome |
|
|
Term
| Papule with “stuck on” appearance |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Malignant Melanoma (asymmetry, borders, color, diameter, evolution) |
|
|
Term
| Firm papule with “dimple sign” when squeezed |
|
Definition
| Benign Fibrous Histiocytoma/Dermatofibroma |
|
|
Term
|
Definition
|
|
Term
|
Definition
| (cerebriform nuclei) Mycosis Fungoides |
|
|
Term
|
Definition
|
|
Term
| Red plaques with silvery scale |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Pruritic, purple, polygonal papules |
|
Definition
|
|
Term
|
Definition
| (necrotic keratinocytes in the dermis) Lichen Planus |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| IgA in tips of dermal papillae |
|
Definition
| Dermatitis Herpetiformis (associated with Celiac disease) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Benign genital wart (condyloma acuminatum) |
|
|
Term
|
Definition
| (haloed keratinocytes in s. granulosum) HPV |
|
|
Term
|
Definition
| Myeloblasts (AML; high grade myelodysplastic syndrome) |
|
|
Term
|
Definition
|
|
Term
| MPO positive (myeloperoxidase) |
|
Definition
|
|
Term
| SBB positive (Sudan black B) |
|
Definition
|
|
Term
| NSE positive (Nonspecific esterase) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| AML promyelocytic type (all trans-retinoic acid treatment) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| bcr-abl, Philadelphia chromosome, CML*, ALL, AML - *required for diagnosis |
|
|
Term
| “soccer ball” or “cracked earth” nuclei |
|
Definition
|
|
Term
|
Definition
| Unmutated CLL (poorer prognosis) |
|
|
Term
|
Definition
| CLL à diffuse large B-cell lymphoma |
|
|
Term
|
Definition
|
|
Term
| Hypercellular bone marrow + peripheral cytopenia |
|
Definition
|
|
Term
| Plethora + intense pruritis after bathing |
|
Definition
|
|
Term
|
Definition
| (throbbing/burning of hands and feet) essential thrombocytosis |
|
|
Term
| “B” symptoms: fever, loss of appetite, weight loss |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Bcl-2, Follicular lymphoma (& DLBCL) |
|
|
Term
|
Definition
| cyclin D1, Mantle cell lymphoma |
|
|
Term
|
Definition
| Endemic Burkitt’s Lymphoma (EBV-associated) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| c-MYC, Burkitt’s lymphoma |
|
|
Term
| Lacunar type RS cell + collagen bands |
|
Definition
| Nodular Sclerosis Hodgkin Lymphoma |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| “punched out” lesions in bone |
|
Definition
|
|
Term
| Hyperviscosity syndrome; Waldenstrom macroglobulinemia |
|
Definition
| Lymphoplasmacytic Lymphoma, over secretion of IgM |
|
|
Term
| >20% plasma cells on WBC differential |
|
Definition
|
|
Term
| Effacement of podocytes only |
|
Definition
|
|
Term
| Effacement of podocytes + focal detachment of epithelial cell |
|
Definition
|
|
Term
| Diffuse capillary membrane thickening + spikes/domes |
|
Definition
| Membranous glomerulonephritis/ glomerulopathy/ nephrits/ idk why this has so many names |
|
|
Term
| Subendothelial and mesangial immune complexes |
|
Definition
| Membranoproliferative glomerulonephritis type I |
|
|
Term
| Ribbon-like deposits on EM, Subepithelial humps, “lumpy bumpy” IF |
|
Definition
| (immune complexes in bm) Membranoproliferative glomerulonephritis type II, (immune complexes above the bm) Acute proliferative glomerulonephritis, Acute proliferative glomerulonephritis, (and, according to our notes, RPGN II) |
|
|
Term
|
Definition
| Goodpasture’s syndrome, RPGN type I |
|
|
Term
| Crescent formation in glomeruli |
|
Definition
|
|
Term
| ANCA-associated glomerulonephritis |
|
Definition
|
|
Term
|
Definition
| IgA Nephropathy (Berger disease), HSP |
|
|
Term
| Diffuse thinning of glomerular bm |
|
Definition
| Thin basement membrane disease (benign familial hematuria) |
|
|
Term
| Defect in alpha-5 chain of type-4 collagen |
|
Definition
| Alport’s disease (X-linked), autosomal forms involve alpha 3 and 4 as wel |
|
|
Term
| Splitting of glomerular bm |
|
Definition
| MPGN Type I, alport's disease |
|
|
Term
| Lamination of lamina densa |
|
Definition
|
|
Term
|
Definition
| Autosomal dominant, polycystin genes (PKD1 and PDK2) |
|
|
Term
|
Definition
| Autosomal recessive Fibrocystin gene (PKHD1) |
|
|
Term
| Cysts at corticomedullary junction |
|
Definition
| Familial Nephronophthisis (Medullary cystic disease complex) |
|
|
Term
|
Definition
| (bacteria, Ca, and Mg—degradation products) Malacoplakia |
|
|
Term
|
Definition
| Syncytiotrophoblasts present in tumor |
|
|
Term
| Testicular tumor positive for AFP +/- A1AT |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Testicular mass + hormonal change (gynecomastia; sexual precosity in kids) |
|
Definition
|
|
Term
|
Definition
| Organ-specific but NOT cancer-specific |
|
|
Term
|
Definition
|
|
Term
| Uniform acanthosis with confluent parakeratosis |
|
Definition
|
|
Term
| Auspitz sign (pinpoint bleeding) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Spongiform pustules of Kogoj |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| IgG antibodies against hemidesmosome proteins |
|
Definition
|
|
Term
|
Definition
| Celicas/ Dermatitis Herpetiformis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Explosive Seborrheic keratosis, normally indicating adenocarcinoma |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Nevoid basal cell carcinoma syndrome |
|
Definition
|
|
Term
| PTCH gene on chromosome 9q22.3l |
|
Definition
| Nevoid basal cell carcinoma syndrome |
|
|
Term
| Sonic Hedge Hog (SHH) gene product mutation |
|
Definition
| Nevoid basal cell carcinoma syndrome |
|
|
Term
| Medullo blastomas, ovarian fibromas, odontogenic keratocysts, intracranial calficiations, rib abnormalities, palmar/plantar pits |
|
Definition
| Nevoid basal cell carcinoma syndrome |
|
|
Term
|
Definition
| Nevoid basal cell carcinoma syndrome |
|
|
Term
| Cup-shaped squamous proliferation and keratin plug |
|
Definition
|
|
Term
| cup-shaped tumor filled with keratin debris |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Melanoma in Asian and African American |
|
Definition
| Acral Lentiginous Melanoma |
|
|
Term
|
Definition
| Dermatofibroma/Benign Fibrous Histiocytoma (BFH) |
|
|
Term
| p16INK4A (CDNK2) mutations |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Prautrier's microabscesses |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Mucin deposited in dermis |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Vitiligo, Psoriasis, Lichen Planus |
|
|
Term
|
Definition
|
|
Term
| Wedge-shaped hypergranulosis |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Dermatitis Herpetiformis disease association |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Acute Myeloid Leukemia (AML) |
|
|
Term
|
Definition
|
|
Term
|
Definition
| T cell markers (seen in Precursor T-cell ALL/LBL) |
|
|
Term
|
Definition
| Polycythemia Vera, Essential Thrombocythemia (50%), Primary Myelofibrosis (PMF) (50-60%) |
|
|
Term
| Large megakaryocytes with highly lobulated nuclei |
|
Definition
| Essential Thrombocythemia (ET) |
|
|
Term
| WBC Toxic granulation, Dohle Body, Cytoplasmic vacuoles |
|
Definition
| Leukemoid Reaction (signs of fighting infection) |
|
|
Term
| Gingival hyperplasia (gum hypertrophy) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| earth or soccer ball nuclei |
|
Definition
| Chronic Lymphocytic Leukemia (CLL) |
|
|
Term
| Most common leukemia in the Western world |
|
Definition
| Chronic Lymphocytic Leukemia (CLL) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Red cell lakes in spleen sinusoids |
|
Definition
|
|
Term
| TRAP(+) lymphocyte cells (Tartrate Resistant Acid Phosphatase) |
|
Definition
|
|
Term
| CD5, CD20 (+) - co-expression |
|
Definition
| Chronic Lymphocytic Leukemia |
|
|
Term
| ↑ basophils in peripheral blood |
|
Definition
|
|
Term
|
Definition
| Primary Myelofibrosis (PMF)) |
|
|
Term
| Wickham striae (oral mucosa) |
|
Definition
|
|
Term
| Reed-Sternburg (RS) cells |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| KSHV/HHV8, and EBV viruses |
|
Definition
| Body cavity Diffuse large B cell lymphoma |
|
|
Term
|
Definition
| Diffuse large B cell lymphoma |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| lacunar type RS cells + collagen bands |
|
Definition
| Nodular Sclerosis Hodgkin Lymphoma |
|
|
Term
| "punched out" bone lesions |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Down Syndrome before the age of 5 (Leukemia association) |
|
Definition
| Acute Megakaryoblastic leukemia |
|
|
Term
| Down Syndrome afer the age of 5 (Leukemia association) |
|
Definition
| Acute Lymphoblastic Leukemia |
|
|
Term
|
Definition
| Chronic Lymphocytic Leukemia |
|
|
Term
|
Definition
| Reed-Sternberg Cell (Hodkins Lymphoma) |
|
|
Term
| Endodermal Sinuses/ Schiller-Duval bodies |
|
Definition
| Yolk Sac Tumor (Endodermal Sinus Tumor) |
|
|
Term
| Eosinophilic hyaline globules containing AFP |
|
Definition
| Yolk Sac Tumor (Endodermal Sinus Tumor) |
|
|
Term
|
Definition
|
|
Term
| Homogenous testicular mass with no hemorrhage or necrosis |
|
Definition
|
|
Term
| most common cancer in men |
|
Definition
|
|
Term
| spike and dome appearance on EM |
|
Definition
|
|
Term
|
Definition
| Membranoproliferative Glomerulonephritis |
|
|
Term
|
Definition
| Membranoproliferative Glomerulonephritis- Type II |
|
|
Term
| Kimmelstiel Wildson nodules |
|
Definition
| Nephrotic syndrome caused by DM |
|
|
Term
| Congo-Red staining with apple-green birefringence under polarized light |
|
Definition
| Systemic Amyloidosis = nephrotic syndrome |
|
|
Term
| crescents ( fibrin/macrophages) in Bowman's Space |
|
Definition
| Rapidly Progressive Nephritic Syndrome |
|
|
Term
| Cortical scarring and blunted calyces of kidney |
|
Definition
|
|
Term
| Thyroidization of the kidney |
|
Definition
|
|
Term
| staghorn calculi in renal calyces in adults |
|
Definition
| Ammonium Magnesium Phosphate Kidney Stone |
|
|
Term
| staghorn calculi in renal calyces in kids |
|
Definition
|
|
Term
|
Definition
| Acute Proliferative (Poststreptococcal, Postinfection) Glomerulonephritis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Infectious endocarditis (think S. aureus!) |
|
|
Term
| Most common cause of all fungal infections |
|
Definition
|
|
Term
|
Definition
| Sporotrichoisis - caused by Sporothrix schenckii |
|
|
Term
| noncancerous laryngeal papillomas |
|
Definition
| Recurrent Respiratory Papillomatosis |
|
|
Term
|
Definition
| Recurrent Respiratory Papillomatosis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| progressive multifocal leukoencephalopathy |
|
|
Term
|
Definition
| erythema infectiousum (erythrovirus/parvovirus B19) |
|
|
Term
| globoside (group P antigen) |
|
Definition
| erythrovirus/parvovirus B19 |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Granuloma inguinale (Donovanosis) |
|
|
Term
| "swimming pool granulomas" |
|
Definition
| Mycobacterium marinum- slow growing/atypical |
|
|
Term
| The only extracellular Mycobacterium |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Loss of temperature sensitivity & (+) lepromin skin test |
|
Definition
| Tuberculoid leprosy (M. leprae) |
|
|
Term
| Most common Rickettsial infection |
|
Definition
| Rickettsial rickettsii- Rocky Mountain Spotted Fever (RMSF) |
|
|
Term
| Severe frontal Headache & centripetal rash |
|
Definition
| Rickettsial rickettsii- Rocky Mountain Spotted Fever (RMSF) |
|
|
Term
| trunk to extremities (centrifugal) rash |
|
Definition
|
|
Term
| localized esher at bite site and centrifugal rash |
|
Definition
| Orientia tsutsugamushi - Scrub Thyphus |
|
|
Term
| co-transmitted w/ Lyme Disease |
|
Definition
| Human granulocytotrophic anaplasmosis (HGA) - Anaplasma phagocytophlilum |
|
|
Term
|
Definition
| Human granulocytotrophic anaplasmosis (HGA) - Anaplasma phagocytophlilum |
|
|
Term
|
Definition
| Borrelia burgdorferi- Lyme disease |
|
|
Term
|
Definition
| Human ewingii erlichiosis (HEE) - Ehrlichia eqingii |
|
|
Term
| distinctive bone pain (shins) |
|
Definition
| Bartonella quintana- Trench Fever |
|
|
Term
| AIDs pt w/ Bacillary peliosis hepatitis |
|
Definition
| Bartonella henselae - Cat Scratch Disease |
|
|
Term
|
Definition
| Leptospira interrogans: Leptospirosis |
|
|
Term
|
Definition
| Treponema pallidum - Syphilis |
|
|
Term
|
Definition
| Treponema pallidum - Syphilis |
|
|
Term
| Jarish-Herxheimer reaction following Penicillin |
|
Definition
| Treponema pallidum - Syphilis |
|
|
Term
| Arthritis/Tenosynovitis & Dermatitis |
|
Definition
|
|
Term
| Most common sexually transmitted pathogen |
|
Definition
| C. trachomatis servars D-K: |
|
|
Term
| large mucoid capsule = virulence factor |
|
Definition
|
|
Term
|
Definition
| Pneumonia: Klebsilla pneuomiae |
|
|
Term
| Urease (+) organism causing kidney stones |
|
Definition
|
|
Term
| contaminated dry powdered infant formula |
|
Definition
| Enterobacter sakazakii (cronobacter) |
|
|
Term
| UTI with swarming motility on agar surface |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Bipolar staining with safety pin appearance |
|
Definition
|
|
Term
|
Definition
| Yersinia pestis- The Plague |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| lung infiltrate, liver involvement, animal exposure |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Francisella tularensis (Tularemia) |
|
|
Term
|
Definition
| Puerperal sepsis (S. pyogenes) |
|
|
Term
| Muriform cells/Medlar bodies |
|
Definition
|
|
Term
| thick-walled, dark brown rounded sclerotic cells |
|
Definition
|
|
Term
| planar splitting division |
|
Definition
|
|
Term
| lesions that resemble cauliflower |
|
Definition
|
|
Term
| mycelial lesions of the tissue |
|
Definition
|
|
Term
| contaminated epidural steroid injections |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Pus with white or black fungal granules/grains |
|
Definition
|
|
Term
|
Definition
|
|
Term
| pteridine that fluoresces bright blue-green under long wave UV light (Wood Lamp) |
|
Definition
| Microsporum (Dermatophyte) |
|
|
Term
| extensive ground-glass changes |
|
Definition
| Pneumocystisi jiroveci pneumonia (PCP) |
|
|
Term
| MCC of morbidity & mortality or AIDs pts |
|
Definition
| Pneumocystisi jiroveci pneumonia (PCP) |
|
|
Term
|
Definition
|
|
