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Block 3
Week 6
25
Biology
Graduate
02/10/2009

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Cards

Term
Bladder filling/emptying is under sympathetic/parasympathetic control, what receptors are involved with each process?
Definition
Sympathetic- b3 relax dome and a1 contracts preprostatic sphincter; Parasym- m2 and m3 receptors induce contractions in detrusor muscle
Term
The external urethral spincter is under voluntary control in micturition, what somatic nerve controls that?
Definition
Pudendal
Term
Why is that hormonal deficiency in women can reduce the effectiveness of the internal and external urethral sphincter as well as various other urinary tract structures?
Definition
Many of these structures have estrogen receptors and will degrade and atrophy without them, leading to problems like trigonitis, urethritis, etc.
Term
What is normal bladder capacity and when do you first feel the urge to void?
Definition
300-600cc; 150-300cc
Term
The brain stem-pons facilitates urination but which part of the brain is responsible for voluntary inhibitory control?
Definition
Cerebral cortex
Term
Which of the following are normal urinary changes that increase with aging - postvoid residual volume, involuntary bladder contractions, nocturia 1-2x/night?
Definition
All of them
Term
In reference to the Inguinal triangle, how do you differentiate between a direct and indirect inguinal hernia?
Definition
Direct begins herniating in the triangle and pressing thru the conjoint tendon and superficial ring; Indirect begins outside the triangle and thus indirectly through the deep inguinal ring and canal(because of a patent processus vaginalis)
Term
The Mullerian (female) duct ____________ if Mullerian Inhibiting factor is produced by sertoli cells.
Definition
Degenerates
Term
The Wolffian (male) duct differentiates if Testosterone is produced by what cells?
Definition
Leydig; the wolffian tracts induce the formation of seminal vesicles, epididymes, vas deferens.
Term
The male internal genital tracts and external genitalia(including prostate) form due to what hormones respectively?
Definition
Testosterone and DHT
Term
What genes induce the zygote to becomes a male and differentiate so?
Definition
TDF/SRY
Term
In the development of the zygote, if there is no MIF or DHT circulating what happens?
Definition
Female sexual development occurs
Term
What percentage of the testis is seminiferous tubules/sertoli cells and leydig?
Definition
80%, 20%
Term
How long does spermatogenesis take?
Definition
64 days, no matter what it cannot be sped up or slowed
Term
What is the functional purpose of prostatic secretions and seminal fluid?
Definition
The alkaline prostatic secretions aid in sperm motility and protect against acidic vaginal environment and the seminal fluid has fructose to give energy to sperm
Term
An infertile male with Sertoli Cell Only Syndrome does not produce sperm and has small testicles, what problems does he have with the leydig cells?
Definition
They are usually normal
Term
If a man suffers from andropause, wilting testosterone production, and he chooses testosterone replacement therapy what must you test for first?
Definition
Prostate cancer
Term
True or False: the product of the SRY gene is a transcription factor that determines the fate of the indifferent gonads in the developing genital system.
Definition
True
Term
The epithelium of the urethra in both sexes is derived from ___________ while the muscle and surrounding connective tissue is derived from splachnic ____________.
Definition
Endoderm, mesoderm
Term
Briefly review Trelease’s lecture on development because there will only be one quiz question on it, no need to know it completely.
Definition
Do it, lazy ass.
Term
Since epithelial-mesenchymal interactions induce differentiation in developing kidneys, which of the following growth factors induce nephron growth - WT1, GDNF, HGF, FGF-2, BMP-7, PAX2, or WNT4?
Definition
All of the them
Term
The forming nephrons in development and thus the kidneys stem from what type of tissue?
Definition
Intermediate mesoderm
Term
Sertoli cells generate inhibin, what is its function?
Definition
Negative feedback on pituitary to reduce secretion of FSH
Term
true or false: estrogen exerts negative feeback at high levels, and positive feedback at low levels.
Definition
false, low=negative, high=positive
Term
describe what layers form the spermatic chord coverings.
Definition
transversalis= deep ring, internal spermatice fascia; internal oblique=cremaster; external oblique=superficial ring,external spermatic fascia.
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