Term
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Definition
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Term
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Definition
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Term
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Definition
| Maxzide-25MG, Dyazide, Maxzide (75 mg triamterene, 50 mg HCTZ) |
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Term
|
Definition
| only generic in USA, Bumex DSC; loop diuretic |
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Term
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Definition
| Edecrin, loop diuretic, Tab; inj, powder for soln. |
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Term
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Definition
| Lasix, loop diuretic; tabs, soln, inj |
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Term
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Definition
| Demadex, loop diuretic; tabs |
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Term
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Definition
| Midamor, K sparing diuretic; tab |
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Term
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Definition
| Aldactone, K-sparing diuretic; tab; BBW: tumorigen |
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Term
|
Definition
| Dyrenium, K-sparing diuretic; cap |
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Term
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Definition
| Diuril, thiazide; tab, susp, inj powder |
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Term
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Definition
| Thalitone, Hygroton; thiazide; tabs |
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Term
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Definition
| HydroDIURIL, Hydro-Par, Ezide, Microzide capsules; thiazide; tab, cap |
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Term
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Definition
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Term
|
Definition
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Term
|
Definition
| thiazide; Zaroxolyn; tab; BBW--do not interchange Zaroxylon tab & other formulations |
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Term
|
Definition
Indications: Suppression of intestinal bacteria. 2) Hepatic coma.
PK: poorly absorbed. Unabsorbed excreted in feces |
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Term
|
Definition
aminoglycoside; Amikin; BBW--Ototoxicity, nephrotoxicity, neuromuscular blockade, Monitoring--toxic > 35 mcg/ml.
Pharmacology: g(-) infections. Irreversible bind 30S subunit.
PK: IM--rapidly absorbed, Peak 12 mcg/ml (250 mg); E: 92% urine
IV--500 mg over 30 min, Peak 38 mcg/ml; repeat inf 7.5 mg/kg q12h |
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Term
|
Definition
aminoglycoside; inj.
A/D: IM--peak in 30-60 min. IV inf over 2 h, same. May accumulate. Peak is 4x's the IM dose.
M/E: 70% urine. |
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Term
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Definition
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Term
|
Definition
aminoglycoside
TB agent
Nephro, oto, neurotoxic
May be 4th drug in initial phase of TB tx. |
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Term
|
Definition
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Term
| Erythromycin & Sulfisoxasole |
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Definition
| Granules for Oral Suspension |
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Term
| Trimethoprim/Sulfamethoxazole |
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Definition
Bactrim, Bactrim DS, Septra DS, Cotrim Pediatric, Sulfatrim
Indications: acute ex of chronic bronchitis, AOM, enteritis, PJP proph, PJP tx, Traveler's diarrhea, UTI |
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Term
|
Definition
| Isonicotinic acid hydrazide; Nydrazid. BBW--hepatitis. Actions--inhibits synthesis of mycolic acids of cell wall. |
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Term
|
Definition
Paser
Pharm: bacteriostatic agains M. tuberculosis. Inhibits onset resistance to streptomycin & isoniazid. Inhibits folic acid synthesis & mycobactin of cell wall, thus reducing iron uptake by M. tuber. |
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Term
|
Definition
Capastat; BBW--ototoxic, nephrotoxic
Pharm: polypeptide AB.
2nd Line antiTB drug |
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Term
|
Definition
Seromycin Pulvules
Inhibits cell-wall synthesis
2nd line TB drug |
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Term
|
Definition
Myambutol
Diffuses into mycob cells.
Monthly eye exams advised |
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Term
|
Definition
Trecator
For active TB resistant to INH, RIF.
Directly observed therapy for all TB pts
Get baseline AST/ALT, glucose, thyroid, eye exam
Give pyridoxine |
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Term
| Tab: 120 mg RIF, 50 mg INH, 300 mg PYR |
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Definition
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|
Term
| Cap: 300 mg RIF, 150 mg INH |
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Definition
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Term
|
Definition
| use with INH, RIF, ETH for 2 mo |
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Term
|
Definition
Mycobutin; inhibits RNA polymerase.
For MAC in HIV pts
Less-potent enzyme induceer than rifampin; may be used in pts on protease inhibitors |
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Term
|
Definition
| Rifadin; Initial tx INH, PYR, RIF, & either streptomycin or ethambutol |
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Term
|
Definition
Priftin
Ong-acting rifamycin that can be used once weekly in continuation phase of tx in carefully selected HIV pts.
85% as potent an enzyme inducer as rifampin |
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Term
|
Definition
Baci-IM. BBW--can cause renal failure
Use limited to infants w/ pneumonia & empyema caused by staph. |
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Term
|
Definition
carbapenem; Doribax.
For complicated IAI, UTIs.
Active against aerobic & anaerobic g(+) and g(-) bacteria. Inhibits cell-wall synthesis. Inactivates multpile essentail PBP, resulting in inhibition of cell-wall synthesis & death. Binds to PBP 2, 3, 4. |
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Term
|
Definition
carbapenem; Invanz; inj
For API, CAP, IAI, SSSIs, UTIs |
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Term
|
Definition
carbapenem; Primaxin I.V., Primaxin I.M.
For LRTI, UTI, IAI, GynI, sepsis, BJI, SSSI, Endoc,
Cilastatin--inhibits dehydropeptidase 1, which inactivates imipenem when given alone. Cilastatin increases urinary recovery of imipenem & decreases renal toxicity. Imipenem high affinity for PBP 1A, 1B, 2,4,5,6. |
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Term
|
Definition
Merrem I.V.
For meningitis, SSSI, IAI |
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Term
|
Definition
1st gen cephalosporin; generic only
cap, tab, powder for oral susp. |
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Term
|
Definition
1st gen ceph; generic only
only formulation: Powder for Injection |
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Term
|
Definition
1st gen ceph; Keflex
tab, cap; powder for oral susp. |
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Term
|
Definition
2nd gen ceph; Raniclor, Ceclor Puvules, Ceclor,
Tab, chewable; tab, ext release; cap; powder oral susp; |
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Term
|
Definition
2nd gen ceph; generic only
Injection, powder for solution |
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Term
|
Definition
3rd gen ceph; Omnicef
Cap, powder for oral susp |
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Term
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Definition
| 3rd gen ceph; Spectrcef tablets |
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Term
|
Definition
4th gen ceph; Maxipime injection
Inj, sol; Inj, powder for solution |
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Term
|
Definition
3rd gen ceph; Claforan injection
Powder for injection; Injection premixed |
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Term
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Definition
2nd gen ceph; generic only
Injection, powder for soln. |
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Term
|
Definition
| 3rd gen ceph; Suprax powder for oral susp |
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Term
|
Definition
2nd gen ceph; generic only
Powder for inj |
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Term
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Definition
3rd gen ceph; Vantin.
Tab, granules for oral susp |
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Term
|
Definition
2nd gen ceph; generic only
Tab, powder for oral susp |
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Term
|
Definition
3rd gen ceph; Fortaz, Ceptaz, Tazicef, Tazidime
Injection, powder for soln; Inj |
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Term
|
Definition
| 3rd gen ceph; Cedax cap, powder for oral susp. |
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Term
|
Definition
| 3rd gen ceph; Cefizox injection; powder for injection |
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Term
|
Definition
| 3rd gen ceph; Rocephin injection, powder for soln |
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Term
|
Definition
2nd gen ceph; Ceftin tab, oral susp
Zinacef injection, powder for injection |
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Term
|
Definition
| 1st gen ceph; Keflex tab, cap, powder for oral susp |
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Term
|
Definition
| fluroquinolone; Cipro, Cipro XR, Proquin XR tab, tax extended release, microcap for oral susp; Cipro I.V. inj sol. BBW: tendinitis & tendon rupture |
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Term
|
Definition
| fluroquinolone; Factive tab |
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Term
|
Definition
fluorquinolone; Levaquin tab, soln, inj soln
2nd line TB drug |
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Term
|
Definition
fluoroquinolone; Avelox tab, Avelox I.V.
2nd line TB drug |
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Term
|
Definition
| fluroquinolone; Noroxin tab |
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Term
|
Definition
| fluoroquinolone; Floxin tab |
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Term
|
Definition
fluoroquinolone; Tequin tab, inj soln
2nd line TB drug |
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Term
|
Definition
alpha beta blocker; Coreg tab
Coreg CR cap, extended release |
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Term
|
Definition
| alpha beta blocker; Trandate tab, inj |
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Term
|
Definition
antiadrenergic-centrally acting. stimulates alpha-adrenoreceptors in brain;
Catapres tab |
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Term
|
Definition
antiadrenergic-centrally acting;
Wytensin tab |
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Term
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Definition
antiadrenergic-centrally acting;
Tenex tab, tab XR |
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Term
| Methyldopa & Methyldopa HCl |
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Definition
antiadrenergic-centrally acting; stimulates alpah-adrenoreceptors in brain;
generic only; tab, inj |
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Term
|
Definition
antiadrenergic-peripherally acting;
generic only; tab |
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Term
|
Definition
antiadrenergic-peripherally acting; alpha-1 blockers;
Cardura tab; Cardura XL tab XR |
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Term
|
Definition
alpha-1 blocker
Minipress cap |
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Term
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Definition
| alpha-1 blocker; Hytrin tab, cap |
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Term
|
Definition
cardioselective beta-blocker
Sectral cap |
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Term
|
Definition
beta-1 selective (cardioselective) blocker;
Tenormin tab
BBW: do not D/C abruptly, or may cause angina and MI. |
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Term
|
Definition
| cardioselective; Kerlone tab |
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Term
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Definition
| beta-1 selective; Zebeta tab |
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Term
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Definition
ISA, long-acting, non-selective;
Cartrol tab
No favorable effect on arrhythmias |
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Term
|
Definition
beta-1 selective with rapid onset, very short duration of action;
Brevibloc injection |
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Term
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Definition
| beta-1 preferential; Lopressor tab, injection. BBW: gradually reduce dose. Bronchospastic dz pts should not receive beta-blockers. Major surgery, Diabetes, Pheochromocytoma: if beta-blocker req'd, give w alpha blocker & only after alpha blocker initiated. Thyrotoxicosis: masks tachy |
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Term
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Definition
| beta-1 prefer; Toprol XL tablet extended release |
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Term
|
Definition
nonselective beta-blocker;
Corgard tab
BBW: exacerbation of ischemic heart disease after abrupt withdrawal |
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Term
|
Definition
beta-1 selective, but in poor metabolizers & high doses, beta-2 also.
Bystolic tab |
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Term
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Definition
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Term
|
Definition
ISA, non-selective beta blocker
Visken tab |
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Term
|
Definition
nonselective beta-blocker;
tab, soln, inj; Inderal LA, InnoPran XL--cap ext rele; Propranolol Intensol--concentrated soln; Inderal injection |
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Term
|
Definition
nonselective beta-blocker & cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties.
BBW: 3 days in facility for ECG, cardiac resuscitation, CrCl.
tab, inj; Betapace, Betapace AF tab, inj |
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Term
|
Definition
nonselective beta-blocker;
BBW: do not abruptly DC
Blocadren tab |
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Term
| Amlodipine Besylate/Benazepril HCl |
|
Definition
| Lotrel cap 2.5, 5, 10 mg amlodipine/10,20, 40 mg benazepril |
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Term
|
Definition
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Term
|
Definition
| Tenoretic 50 Tab, Tenoretic 100 Tab (50, 100 mg atenolol/25 mg chlorthalidone) |
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Term
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Definition
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Term
| Bisoprolol Fumarate & HCTZ |
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Definition
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|
Term
| Candesartan Cilexetil & HCTZ |
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Definition
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Term
|
Definition
| Capozide 25/15, Capozide 50/15, 25/25, 50/25 |
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Term
| Clonidine & Chlorthalidone |
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Definition
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|
Term
| Enalapril Maleate & Felodipine |
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Definition
| Lexxel Extended-Release Tab |
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Term
| Enalapril Maletate & HCTZ |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
|
Definition
| Accuretic, Quinaretic tab |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
|
Definition
dihydropyridine
Cleviprex injection |
|
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Term
|
Definition
| Cardizem tab, inj, powder for inj; Cardizem LA tab, extended release; Cardizem CD, Cartia XT, Dilacor XR, Dilt-CD, Dilt-XR, Diltia XT, Diltzac, Taztia XT, Tiazac capsules, extended-release; |
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Term
|
Definition
dihydropyridine
generic only |
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Term
|
Definition
dihydropyridine
DynaCirc CR, DynaCirc tab, cap |
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Term
|
Definition
| Cardene cap, cap (sust-release), inj |
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Term
|
Definition
| Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia XL tab (ext release); Procardia cap |
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Term
|
Definition
| CCB; generic cap (liquid filled) only |
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Term
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Definition
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Term
|
Definition
| tab, inj; Calan tab; Calan SR, Calan-HS, Isoptin SR tablet (ext release); Verelan, Verelan PM capsule (ext release); |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
|
Definition
direct renin inhibitor--decreases plasma renin activity
Tekturna |
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Term
|
Definition
selective aldosterone receptor antagonist
Inspra tab |
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Term
|
Definition
peripheral vasodilator
Apresoline tab, injection |
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Term
|
Definition
peripheral vasodilator
generic tab only |
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Term
|
Definition
1,4 benzodiazepine; antianxiety agent
Xanax, Xanax XR tab, Alprazolam Intensol sol. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Valium tab; Diastat gel (rectal) |
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Term
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Definition
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Term
|
Definition
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Term
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Definition
macrolide; binds 50S ribosomal subunit; does not affect nucleic acid synthesis
Zithromax tab, powder for oral susp, inj; Zmax powder for ext release oral susp; |
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Term
|
Definition
macrolide; binds 50S ribosomal subunit & inhibits protein synthesis
Biaxin tab, granules for oral susp; Biaxin XL ext release tab; |
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Term
|
Definition
macrolide; inhibits protein synthesis by binding 50 S ribosomal subunit. Does not affect nucleic acid synthesis.
Erythrocin Stearate tab; |
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Term
|
Definition
| cap (delayed release); Ery-Tab, PCE Dispertab tab (delayed release); Erythromycin Filmtab tab (film-coated); |
|
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Term
| Erythromycin ethylsuccinate |
|
Definition
| E.E.X. 400 Filmtab tablets; E.E.S. 400 Liquid susp, oral; EryPed Drops powder for susp; EryPed 200 powder for susp; E.E.S. Granules for oral susp; EryPed 400 powder for oral susp. |
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Term
|
Definition
Ketolide; structurally related to macrolides; blocks protein synthesis by binding 23S RNA of 50S ribosomal subunit.
Ketek tab; oral |
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Term
|
Definition
| Lincosamide; binds exclusively to 50S ribosomal subunit & suppresses protein synthesis. Indicated for: anaerobes, pneumococci, serious infections caused by strep, pneumococci, staph. Reserve for pen allergic. Serious resp tract inf & serious SSTI caused by strep/staph. |
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Term
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Definition
inhibits cell wall synthesis;
Vancocin pulvules, powder for inj; Vancoled powder for inj; |
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