Term
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Definition
| enz required for cutting out a mis-paired base after replication is finished |
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Term
| photoreactivation repair protein |
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Definition
| *removes thymine dimers caused by UV light |
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Term
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Definition
*C to T polymorphisms, G to A polymorphisms
*same class of NA |
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Term
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Definition
| *molecular lesions formed from ADENINE or GLYCINE bases in DNA via photochemical rxns |
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Term
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Definition
| *a process by which genetic material carried by an individual cell is altered by the incorporation of foreign (exogenos) DNA into its genome |
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Term
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Definition
| *extra bonds formed between THYMINE or CYTOSINE in DNA (cause of mutations) |
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Term
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Definition
| *uses sunlight to prevent mutations |
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Term
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Definition
| a chemical reaction requiring E that can alter which NA is base paired to another NA |
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Term
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Definition
| *the repair mech in DNAP that cuts out DNA to repair it when there is a mismatched base pair |
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Term
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Definition
| repair that creates random DNA |
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Term
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Definition
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Term
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Definition
| *a spontaneous chemical analog that can alter which NA is base paired to another NA |
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Term
| double strand break repair |
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Definition
| DNA repair mech helps prevent the rapid formation of new species |
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Term
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Definition
| *DNA consists of very large arrays of tandemly repeating, noncoding DNA |
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Term
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Definition
| slipped mispairing would not cause a deletion in this DNA sequence |
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Term
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Definition
*purine to pyrimidine
*pyrimidine to purine
G to C polymorphisms, T to A polymorphisms
*C to A polymorphisms, T to G polymorphisms
*diff class of NA |
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Term
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Definition
| synt of RNA molecule from DNA template |
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Term
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Definition
| cellular process that is always mutagenic |
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Term
| excision/ mismatch repair |
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Definition
| the repair mech uses Cytosine methylation to know which strand is newer or which has error |
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Term
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Definition
| the scientific study of heredity |
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Term
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Definition
| *method used to analyze protein interactions on a genomic scale |
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Term
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Definition
| *detect binding between protein and DNA |
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Term
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Definition
| *approach that could help predict if two genes might be epistatic using information about protein amount |
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Term
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Definition
| *an approach that could help predict if two genes might be epistatic using information about transcript accumulation |
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Term
| interaction cluster/ modules |
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Definition
| tool that is used to test if a gene correlates to other genes controlling the phenotype |
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Term
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Definition
| *work in trans to move DNA |
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Term
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Definition
| telomere variation between species is studied in this field |
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Term
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Definition
| centromeres w/in a species studied in this field |
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Term
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Definition
| combining different DNA seq to get a whole genome |
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Term
| gene knockout library/ collection |
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Definition
| *used to test hypothesis generated by transcriptomics |
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Term
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Definition
| *can move DNA between them if 2 work together |
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Term
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Definition
| *the global study of all genes simultaneously |
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Term
| next generation sequencing |
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Definition
| *tool used to both measure RNA abundance and seq a whole genome |
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Term
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Definition
| *genetics cares predominantly about |
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Term
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Definition
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Term
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Definition
| *key genes that connect clusters of interacting genes |
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Term
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Definition
| centromere variation within a species studied in this field |
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Term
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Definition
| *influenced by a single gene |
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Term
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Definition
| *mutation repaired by a protein that uses light |
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Term
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Definition
| *type of transposable element |
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Term
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Definition
| *involved passing a DNA seq through a small nanopore and measuring the change in current (shape) |
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Term
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Definition
| *small, selfish gentic elements |
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Term
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Definition
| *technique used to determine series of base pairs in DNA |
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Term
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Definition
| DNA can be moved but cannot move itself |
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Term
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Definition
| protein involved in retrotransposon but not DNA transposon movement |
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Term
| TTA,GAA,GAA,GAA,GAA,GAA,CTT |
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Definition
| *slipped mispariring would cause an insertion/deletion in this DNA seq |
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Term
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Definition
| *sole component of polypeptide |
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Term
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Definition
| *translational component comprised primarily of protein |
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Term
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Definition
| *RNA involved in DNA replication |
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Term
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Definition
| *DNA protein involved in packaging |
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Term
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Definition
| *small chem involved in both transcriptional/ translational control |
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Term
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Definition
| *bonds to the prokaryotic promoter to ID the transcription start |
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Term
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Definition
| makes new DNA and can do proofreading and cut out RNA |
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Term
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Definition
| allows for rapid regulation of a process |
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Term
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Definition
| *genomics tool studies protein-proetin interact in test tube |
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Term
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Definition
| *a chemical approach to seq a genome |
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Term
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Definition
| *a field of research focused on studying complex traits |
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Term
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Definition
| activity prevents mutations both during and after DNA replication |
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Term
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Definition
| prevents mutations caused by UVB |
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Term
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Definition
| the only direct DNA repair mech |
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Term
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Definition
| splits thymine dimers in the presence of visible light |
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Term
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Definition
| prevents mutations during replication |
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Term
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Definition
| a chem process that can alter NA bind sites that is inherent to the NA |
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Term
| double strand break repair |
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Definition
| broke DNA initiates homologous recomb between sister/non chromatids and results in rejoining of broken ends DNA |
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Term
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Definition
| main component of func centromeres |
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Term
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Definition
| form main structural constituent of heterochromatin |
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Term
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Definition
| repair mech cuts out DNA to repair when have mismatched(unnatural) base pair in DNA |
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Term
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Definition
| an approach that could help predict if 2 genes might be epistatic using protein info |
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Term
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Definition
| genomics tool studies protein-protein interactions in living cells |
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Term
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Definition
| if yeast cells test + for particular reporter protein, then 2 proteins had to have interaction w/in yeast nuc |
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Term
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Definition
| bait inserted upstream b4 promoter, prey fused to activating domain (activates reporter) |
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Term
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Definition
| analyzes proteins on genomic scale |
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Term
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Definition
| study of structure and func of proteins in human body |
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Term
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Definition
| a genomic analysis of mRNA accumulation |
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Term
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Definition
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Term
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Definition
| allows a piece of DNA to become mobile |
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Term
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Definition
| enz recognizes host DNA and cuts/ glues transposons in/out of genome |
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Term
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Definition
| field of research interested in change (centromeres) |
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Term
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Definition
| sim/diff in gene content, func, and organization amoung genomes of diff org |
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Term
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Definition
| organization/ seq of genetic info in a genome |
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Term
| gene knockout library/ collection |
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Definition
| can be used to ask how many genes are essential in org |
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Term
| gene knockout library/ collection |
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Definition
| tests if a gene alters a phenotype |
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Term
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Definition
| a piece of DNA that is mobile |
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Term
|
Definition
| the study of whole genomes including genes/ func |
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Term
| next generation sequencing |
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Definition
| measures global seq polymorphism or transcript abundance (microarray) |
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Term
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Definition
| what genomics is trying to predict |
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Term
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Definition
| leads to hairpin form on the RNA during transcription |
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Term
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Definition
| proteomics/transcriptomics have led research to puzzle about this |
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Term
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Definition
| large scale comparison of DNA seq of populations |
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Term
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Definition
| pair of abnormally chem bonded thymine bases in DNA resulting from damage by UV radiation |
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Term
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Definition
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Term
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Definition
| encode the ability to move themselves around and /or replicate themselves w/in genome |
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Term
|
Definition
| studies all chem /in a cell |
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Term
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Definition
| changes AA b/c changed base |
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Term
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Definition
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Term
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Definition
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Term
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Definition
*the fraction of the phenotypic variation that is caused by genetically inherited variation
*determines the response to selection
*describes the ability to predict the progeny phenotype from parents phenotype |
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Term
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Definition
| *genetic distance between ind |
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Term
| phylogenetic tree does not show |
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Definition
*time since last common ancestor
*direction of evolution of optimal genotype
*who was the last common ancestor
*rate of evolution |
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Term
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Definition
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Term
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Definition
*own DNA inserted
*important for finding sp seq of DNA |
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Term
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Definition
*insert DNA
*restriction enzymes
*choose fragments, move to Lac Z
*multiple cloning site |
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Term
|
Definition
*w/ AMPr= untransformed cells
* view diff DNA/ vector that got in |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
1) CG and AT present in different amounts
2) purine A = pyrimidine T
purine G = pyrimdine C
*purine (A,G) = pyrimidine (C,T) |
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Term
|
Definition
*triosphosphate
*dideoxyribose
*flourescent tag
**lacks 3’OH (stop synth, see last base) |
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Term
| molecule that regulates transcription by directly interacting w/ TF |
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Definition
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Term
|
Definition
*deoxyribose
*triosphosphate |
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