Term
| mortality is high (highest of any disease) |
|
Definition
|
|
Term
| one or more manic episodes; no depression required, but frequently occurs |
|
Definition
|
|
Term
| hypomania; one or more depressive episodes; without psychosis |
|
Definition
|
|
Term
| hypomanic episodes and without major depression; low grade cycling which interferes with functioning |
|
Definition
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|
Term
| diagnosis doesn't fit in other subtypes; significantly impair and adversely affect quality of life |
|
Definition
|
|
Term
| Used primarily in maintenance |
|
Definition
|
|
Term
| considered drug of choice in treating patinets with "pure" mania |
|
Definition
| Lithium (eskalith, lithobid) |
|
|
Term
| MOA: nature of action uncertain; appears to alter cation transport across cell membrane; influences uptake of serotonin and/or norepinephrine |
|
Definition
|
|
Term
| tremors, polydipsia, polyuria, nausea, diarrhea; weight gain, decrease memory, confusion; hypothyroidism, transient leukocytosis; teratogenic risk |
|
Definition
|
|
Term
| particularly effective in patients who rapid cycle, mixed episodes, schizoaffective; used also in seizure control; used in patients with behavior problems as result of organic brain disease; head injuries |
|
Definition
|
|
Term
| exact MOA unknown; may cuase increase availability of GABA to neurons of the brain; may mimic action of GABA at postsynaptic receptor sites |
|
Definition
|
|
Term
| nausea, tremors, weight gain; lethargy, alopecia; benign increase in liver function tests; rare: hepatotoxicity, agranulocytosis, pancreatitis |
|
Definition
| Valproate adverse effects |
|
|
Term
| is structurally similar to imipramine, tricyclic antidepressant; used to treat seizure disorders and trigeminal neuralgia; is used in schizoaffective disorders; has properties of muscle relaxant, antidiuretic, antiarrhythmic, anticholinergic |
|
Definition
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|
Term
| MOA not really understood; effects may be due to stabilizations of sodium channels on neurons |
|
Definition
|
|
Term
| nausea, sedation, dizziness, elevated liver function tests |
|
Definition
| Carbamazepine adverse effects) |
|
|
Term
| use in partial seizures; used in bipolar |
|
Definition
| Oxcarbazepine (Trileptal) |
|
|
Term
| hyponatremia, steven-johnson syndrome, thrombocytopenia, leucopenia; dizziness, somnolence, diplopia, fatigue; nausea, confusion, nervousness |
|
Definition
| Oxcarbazepine adverse effects |
|
|
Term
| primary use is for adjunctive treatment of partial seizures in adults with epilepsy; no problems with wt. gain, tremors, or memory deficit; may be effective as antidepressant |
|
Definition
|
|
Term
| acts on sodium channels to stabilizer neuronal membranes, therefore, inhibiting transmitter release of glutamate |
|
Definition
|
|
Term
| nausea nad vomiting, dizziness, ataxia, blurred vision; skin rash, severe Steven-Johnson Syndrome (may be fatal) |
|
Definition
| Lamotrigine (Lamictal) adverse effects |
|
|
Term
| nightmares or dreams may become more vivid; literature shows taper up to 13 mg |
|
Definition
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