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Biopsychology
Biological Psychology
199
Psychology
Undergraduate 2
12/09/2010

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Term
Franz Joseph Gall
Definition
Described "phrenology" as the belief that certain areas of the brain performed specific functions, and the development of these functions was differential to individuals.
Term
Cranial nerve I
Definition
Olfactory- a sensory nerve for the nose
Term
Cranial Nerve II
Definition
Optic- a sensory nerve for carrying information from the eye
Term
Oculomotor Nerve
Definition
Cranial nerve #3, controls eye movement (motor)
Term
Trochlear Nerve
Definition
Cranial Nerve #4, controls the movement of the eye (motor)
Term
Trigeminal Nerve
Definition
Cranial nerve #5- facial nerve plus chewing, swallowing, and biting. (sensorimotor)
Term
Abducens Nerve
Definition
Cranial Nerve 6-Controls a muscle of the eye-(motor)
Term
Facial Nerve
Definition
Cranial Nerve 7- responsible for facial expression and gustation (sensorimotor)
Term
Auditory Nerve
Definition
Cranial Nerve 8- receives input from areas of balance and audition (sensory)
Term
Glossopharyngeal Nerve
Definition
Cranial Nerve 9- throat muscles & taste from the last 1/3 of the tongue (sensorimotor)
Term
Vagus Nerve
Definition
Cranial Nerve 10-organs (sensorimotor)
Term
Spinal Accessory Nerve
Definition
Cranial Nerve 11- muscles of the neck (motor)
Term
Hypoglossal Nerve
Definition
Movement of the tongue (cranial nerve 12, motor)
Term
Telencephalon
Definition
most advanced part of the brain. Contains the four lobes, and is most massive of all brain areas.
Term
Frontal Lobe (general functions)
Definition
executive function, planning, planning motor control, prioritization, contains primary motor cortex
Term
Parietal Lobe (general functions)
Definition
Attention, contains primary somatosensory cortex, spatial processing, location
Term
Occipital
Definition
Primary visual cortex.
Term
Temporal Lobe (general functions)
Definition
hearing, understanding, object recognition, knowledge & major association cortices
Term
Layerization of the Cerebral Cortex
Definition
1-axons incoming from other brain areas
2-densely packed stellate cells
3. loosely packed stellate cells and intermediate sized pyramidal cells
4. densely packed stellate cells. No pyramidal cells
5. Very large pyramidal cells, a few loosely packed stellate cells
6. Pyramidal cells of various sizes and stellate cells
Term
Cytoarchitectonic Mapping
Definition
Broadman- made maps of cell types & densities
Term
The Limbic System
Definition
Amygdala- emotion
Hippocampus- Memory acquisition
Term
The Basal Ganglia (parts)
Definition
Caudate Nucleus, Putamen, Thalamus, Hypothalamus, Globus Pallidus responsible for movement, stabilization, associating stimulus & action
Term
Diencephalon (contents)
Definition
Thalamus, Hypothalamus, and Pituitary
Term
Thalamus
Definition
Sensory hub/highway to brain. All senses processed THROUGH thalamus
Term
Hypothalamus
Definition
controls autonomic and endocrine system. 4 F's= Fighting, Fleeing, Feeding, and (F) mating
Term
Mesencephalon (parts)
Definition
Tectum, Tagmentum
Term
Tectum
Definition
"roof" inferior and superior colliculus. Inferior colliculus= sound info superior colluculus = visual maps and auditory maps, integration,
Term
Superior Colliculus
Definition
visual maps & auditory maps, integration, location in space (quick)
Term
Inferior Colliculus
Definition
Sound information
Term
Metencephalon (parts)
Definition
Pons, cerebellum
Term
Pons
Definition
responsible for sleep, portions of the reticular formation, arousal, communication with cerebelum, pons limits motor signals in respons to dreams
Term
Cerebellum
Definition
Motor, coordinated movements, fine motor control, input from all sensory modalities
Term
Myelencephalon
Definition
primitive brain area, medulla oblongata, HR, Respiration rate, blood pressure, vital functions
Term
Somatic Nervous System
Definition
voluntary nervous system
Term
Autonomic Nervous System
Definition
involuntary nervous system, controls smooth muscle
Term
DERMATOMES
Definition
AREAS OF SKIN INNERVATED BY X NERVE
Term
SPINAL CORD (LAYOUT)
Definition
MIDDLE IS GREY MATTER, TWO DORSAL HORNS (SENSORY) TWO VENTRAL HORNS (MOTOR)
Term
DORSAL SPINAL CORD
Definition
RECEIVES & SENDS SENSORY INFORMATION
Term
VENTRAL SPINAL CORD
Definition
SENDS & RECEIVES MOTOR INFORMATION
Term
SOMATIC NERVOUS SYSTEM (MUSCLE TYPE)
Definition
CONTROLS SKELETAL MUSCLE
Term
SYMPATHETIC NERVOUS SYSTEM
Definition
ACTIVATION! PRIMING FOR FIGHTING, RAISES HR, BP, ECT
Term
PARASYMPATHETIC
Definition
CALM NERVOUS SYSTEM, AIDS IN DIGESTION
Term
BRAIN PRINCIPLE 1/8 INTEGRATION AND OUTPUT
Definition
At any given time, a number of inputs will be received. True at system level, organismal level, and cellular level. All inputs will be integrated and a specific output will be given based on results of integration
Term
BRAIN PRINCIPLE 2/8 Sensory & Motor Division
Definition
these two natures are separated! One gyrus will control motor, one gyrus will sense it. Same with the dorsal and ventral horns of the spinal cord.
Term
BRAIN PRINCIPLE 3/8 Crossed Circuits
Definition
the right side of the world is controlled by the left side of the brain, the left side of the world is controlled by the right side. Occurs in ocular div. as well
Term
BRAIN PRINCIPLE 4/8 Symmetry & Asymmetry
Definition
The brain is both symmetrical and asymmetrical. Left + right side for EVERY structure, however the functions are distributed asymetrically
Term
BRAIN PRINCIPLE 5/8 Excitation & Inhibition
Definition
The brain works through excitation and inhibition at the cellular level, system level, and organismal level.
Term
BRAIN PRINCIPLE 6/8 Duplication
Definition
Duplication of systems ensures redundant and reliable function
Term
BRAIN PRINCIPLE 7/8 Heirarchy & Parallels
Definition
different systems both work ascendingly & concurrently
Term
BRAIN PRINCIPLE 8/8 Localization & Distribution
Definition
Functions are both localized and distributed, areas mainly responsible, however in conjunction with others.
Term
Axon Hillock
Definition
closest to axon, generates & begins action potential
Term
Site of Manufacture for Neurotransmitters
Definition
cell body
Term
Axodendritic Synapsing
Definition
Axon to dendrite
Term
Dendritic Spines
Definition
Increase surface area of dendrite, more binding area
Term
Unipolar Neuron
Definition
one entry, one exit to cell body. Tend to be sensory
Term
Bipolar neurons
Definition
two exits/entries to cell body
Term
Multipolar neurons
Definition
multiple inputs!, still only 1 axon, receives info from many different cells
Term
Pyramidal Cell
Definition
deeper layers of cortex, integrate info coming from higher layers of the cortex
Term
Perkinje Cells
Definition
Extremely extremely complex cell that is found in the cerebellum and integrates ALOT of information for fine motor movement
Term
Sensory subtype neuron
Definition
sensory
Term
Motor subtype neuron
Definition
efferent, to muscle. Usually multipolar, synapses with muscle
Term
Interneuron
Definition
neuron to neuron, most neurons are interneurons
Term
Ependymal Cells
Definition
on walls of ventricles, present in central canal of spinal cod, produce CSF, carry particles, nutrients, waste
Term
Astrocytes
Definition
provide physical structure to CNS, keep things in place, anchor to circulatory system, form the BBB, act as buffer, feeds neurons, removes excess neurotransmitters, disposes of wastes.
Term
Microglia
Definition
originate in bloodstream, migrate to brain, release growth factor act as phagocytes (eat foreign matter, digest things)
Term
Myelin Sheath Glia
Definition
Oligodendrocytes, Schwann cells
Term
Oligodendrocytes
Definition
-provides myelin sheath in the CNS wraps itself AROUND MANY NEURONS, many axons
Term
Schwann Cells
Definition
wraps around only one axon, not full axon, guide regrowth of severed axons. "outline path"
Term
Multiple Sclerosis
Definition
Immune system attacks myelin sheath, presenting symptoms can be varied depending on brain area experiencing degeneration
Term
Amyotrophic Lateral Sclerosis
Definition
myelin sheath degeneration in peripheral neurons
Term
Microtubules
Definition
support, maintain shape, transport stuff all way down axon to terminal
Term
Tau Proteins
Definition
stabilize microtubules
Term
Gated Channel
Definition
gates controlling movement can be opened or closed depending on neurotransmitter activity
Term
Pump
Definition
ATP powered passages that have specific mechanisms to pump things in and out, depending on co-presence of other ions or ATP
Term
Huntington's Chorea
Definition
dominant gene disease that attacks the basal ganglia
Term
Resting potential
Definition
-70mv maintained by DIFUSSION, tendency for substances moving from areas of high concentration to low concentration, voltage gradient: ions tend to move from areas of higher charge to areas of lower charge
Term
-70Mc
Definition
Term
-70Mv
Definition
K+ and potasium are present in large quantities inside membrane. Outside has low content of K+ and high content of Cl- and Na+. Electrostatic pressure acts on K+ and force of difussion cancel e/o out
Term
Graded Potential
Definition
small voltage fluctuations, restricted to vicinity, brief change in electrical charge
Term
Hyperpolarization
Definition
increase in electrical charge, inhibitory potential, IPSP
Term
Depolarization
Definition
decrease in electric charge, caused by EPSP
Term
Distance from Axon Hillock
Definition
far = small effect near= larger effect.
if IPSP>EPSP, no action potential
EPSP > IPSP = fire!
Term
Action Potential at -50mV
Definition
1. Na+ channels open
2. Na+ rushes in! forced in by electro & diffusion
3. K+ begins to leave cell
4. At peak, NA+ close and clamp, no more Na+ enters cell
5. K+ continues to leave cell (difussion)
6. Overshoots negativity (refractory)
Term
Acetylcholine Precursor
Definition
Choline
Term
Acetylcholine EPSP/IPSP?
Definition
excitatory
Term
Nicotinic Acetylcholine Receptors
Definition
Ionotropic. Also react to nicotine
Term
Muscarinic Acetylcholine Receptor
Definition
Metabotropic
Term
Muscarinic AcH Location
Definition
found in CNS, manage learning
Term
Monoamines
Definition
include dopamine, sero
Term
Monoamine Pathway
Definition
Tyrosine--> L-Dopa-->Dopamine-->norepi-->epi
Term
Dopamine precursors
Definition
L-Dopa, Tyrosine
Term
Rate Limiting Factor (neurotrans synthesis)
Definition
by limiting a precursor, the amt. of neurotrans can be controlled. Also, the enzymes can be controlled for the same effect.
Term
Dopamine (effect)
Definition
can be both inhibitory and excitatory
Term
Dopamine (receptor type?)
Definition
ALL METABOTROPIC
Term
Nigrostriatal Pathway of Dopamine
Definition
begins in substatia nigra, ends in the cuadate & putamen. Main function: control of movement. Initiating & stopping
Term
Mesolimbic Pathway
Definition
Ventral Tagmental Area with terminals in the limbic system, and the nucleus accumbens. *REWARD, *MEMORY, *ADDICTION
Term
Mesocortical Pathway
Definition
VTA--> frontal lobes. Fxn not well understood
Term
Tuberoinfindibular Pathway
Definition
begins: hypothalamus ends: pituitary (secretion of hormones)
Term
Origin of Norepinephrin
Definition
Locus Coreuleus
Term
Terminals of Norepinephrine pathways
Definition
everywhere
Term
Norepinephrine receptor (type?)
Definition
all metabotropic, respond to epinephrine too.
Term
Functions of norepinephrine & epi
Definition
VIGILANCE, emotions, Increased NE: mania, too little ne: depression
Term
Axonal Varicosities
Definition
bead like swellings along axon that release norepi
Term
Serotonin precursor
Definition
tryptophan
Term
Serotonin receptor (types?)
Definition
those involved in vomiting & nausea are ionotropic, the rest are metabotropic
Term
Locations for Serotonin
Definition
Raphe Nucleus-->
Dorsal raphe--> projections to basal ganglia
Medial raphe--> projects to hippocampus
projects to cortex
Term
Functions of Serotonin
Definition
depression, anxiety, apettite, 5-HT neuromodulator?
Term
Glutamate
Definition
main excitatory neurotransmitter
Term
Glutamate receptor (types?)
Definition
1 metabotropic, 3 ionotropic
Term
NMDA receptor for Glutamate
Definition
a complex glutamate receptor involved in learning. Both ligand and voltage dependent! Wire together fire together
Term
GABA
Definition
hyperpolarizes cells
Term
GABA-a receptor (type?)
Definition
ionotropic
Term
GABA-b receptor (type?)
Definition
metabotropic
Term
Precursor supplementation
Definition
agonist
Term
interfering w/production cascade (enzyme blockade)
Definition
antagonist
Term
Prevention of storage
Definition
antagonist
Term
stimulate release of a neurotransmitter (phrm)
Definition
agonist
Term
inhibit release of a NT (pharm)
Definition
antagonist
Term
Stimulate post-synaptic receptors
Definition
agonist
Term
block post synaptic receptors
Definition
antagonist
Term
Stimulate autoreceptors
Definition
initiate negative feedback cascade--> antagonist
Term
Block autoreceptors
Definition
ruin negative feedback cascade--> agonist
Term
Reuptake inhibition
Definition
agonist
Term
Prevent breakdown
Definition
agonist
Term
Direct Action of a Pharm
Definition
takes place of NT, binds competitively
Term
Indirect action in a pharm
Definition
attaches to receptor at a DIFFERENT site, potentiates
Term
Lipid Solubility
Definition
increases absorption
Term
Depot binding
Definition
decreases bioavailability
Term
Physical Dependence
Definition
increased receptors, unpleasant withdrawal symptoms
Term
Psychological dependence
Definition
when a drug induces a pleasure state, people may continue to seek the drug to maintain state. CRAVING
Term
Alcohol and Behavior
Definition
usually, urge comes in, frontal lobes hold you back
with alcohol, urge comes in, but circuits to hold you back are not available to hold you back, so you ignore future consequences
Term
Nucleus Accumbens
Definition
ADDICTION
Term
Hippocampus
Definition
memory acquisition
Term
Critical Period
Definition
a period of time where neurons are particularly plastic
Term
Vitreous humor
Definition
fills eyeball
Term
myopia
Definition
eye is longer, images focuses in front of retina not on it, "shortsightedness"
Term
Hyperopia
Definition
eye is shorter, image focuses behind the retina (farsightedness)
Term
Cataract
Definition
clouding of the lens
Term
6 Layers of the retina
Definition
1. retinal ganglion cells
2. Acamcrine cells
3. Bipolar cells
4. Horizontal cells
5. Cone
6. Rod
Term
Complexity progression in the retina
Definition
most complex outside, simplest towards the back
Term
Rod
Definition
light sensitive
Term
Cone
Definition
color sensitive
Term
Cone to ganglion convergence
Definition
low convergence, high specificity
Term
Rod to ganglion convergence
Definition
high convergence, low specificity
Term
Protonopia
Definition
most common, deficit in long wavelength cone pigment (red)
Term
Deuteronopia
Definition
green
Term
Tritanopia
Definition
blue
Term
Rhodopsin
Definition
light hits rhodopsin, rhodopsin breaks, channels close, cells hyperpolarize, secretion of glutamate stops!
Term
Rods/Cones in the dark
Definition
release glutamate because rhodopsin and cyclic AMP are keeping the channels open
Term
Receptor hyperpolarization of bipolar cells
Definition
usually, the receptors inhibits the bipolar cells. If the rhodopsin is bleached and the photoreceptor stops inhibiting the bipolar cell, it will FIRE
Term
Geniculostriate pathway
Definition
optic nerve--> optic chiasm--> optic tracts--> thalamus--> lateral geniculate nucleus--> optic radiation--> primary visual cortex
Term
Visual field decussation
Definition
temporal retina are ipsilateral, nasal retina are contralateral
Term
Magnocellular layers of the LGN
Definition
MOVEMENT
Term
Parvocellular layers of the LGN
Definition
color & detail
Term
Tectopulvinar system
Definition
fed by magnocellular cells, detects MOVEMENT, sends info to superior colliculus, used for eye tracking. superior collic-->pulvinar area of the thalamus--> parietal. BYPASSES LGN and terminates in the optic textum. ALL INFO CARRIED BY THIS SYSTEM IS FROM RODS
Term
Superior Colliculus as related to vision
Definition
contains a retinotropic crude map similar to the lgn important for SACCADIC EYE MOVEMENTS and attention. ORIENTING REFLEXES
Term
Calcarine Sulcus
Definition
receives alot of info from fovea.
Term
Simple Cell (visual cx)
Definition
best stimulation is AN ORIENTED BAR OF LIGHT
Term
Complex cell (visual sys)
Definition
oriented bar of light MUST be moving in a specific direction
Term
End-Stopped cell (visual sys)
Definition
bar of light of a specific orientation AND specific length
Term
Hypercomplex cells
Definition
smaller area of activity, indiscriminate (so not really that hypercomplex)
Term
Hemispheric specialization for frequencies.
Definition
Left: better at high spatial frequencies
right: better at low spatial frequencies
Term
Dorsal Stream
Definition
fast response, visually guided actions, magnocellular input, superior colluclus, absolute metrics, moment to moment, location in space
Term
Ventral Stream
Definition
slow response, conscious, parvocellular & magnocellular input, scene-based metrics, long term representation, object recognition & association
Term
Medial Superior Temporal Area
Definition
acknowledges continuity of MOVING images, specific kinds of motions
Term
Middle Temporal (mt)
Definition
perception of movement)
Term
Damage to MT or MST
Definition
akinetopsia (inability to detect movement)
Term
Akinetopsia
Definition
inability to detect movement
Term
Balints Syndrome
Definition
damage of dorsal path. Parieto-occipital lesion at junction. Includes optic ataxia: visually guided actions impossible, ocular apraxia: fixating, scanning, initiating eye movements would be difficult, and simultagnosia: inability to see more than one object at a time
Term
Simultagnosia
Definition
inability to see more than one object at a time
Term
Ocular Apraxia
Definition
fixating, scanning, initiating eye movements difficult
Term
Optic Ataxia
Definition
visually guided actions are impossible
Term
Optic Ataxia exclusive to the parietal lobe
Definition
will be unilateral
Term
Dorsal stream damage
Definition
hemispatial neglect results from right hemis. damage. Inability to respond or attend to people or objects in contralesional space.
Term
Ventral stream heirarchy
Definition
increases in complexity! Dots--> shapes--> blobs--> items
Term
Visual Agnosia
Definition
cannot recognize objects presented in a visual modality
Term
Apperceptive Agnosia
Definition
visual form agnosia, perception of shape is difficult
Term
Associative agnosia
Definition
can identify shapes but not what they are (damage further near temporal lobe)
Term
Appercetive agnosia and Global Shape Properties
Definition
cannot detect global shape properties
Term
Associative Agnosia and Object Drawing from Memory
Definition
cannot draw from memory
Term
Category Specific Visual Agnosia
Definition
subtype of associative agnosia. has problems recognizing some objects but not others. A problem of high differentiation vs. low differentiation
Term
Prosopagnosia
Definition
inability to recognize faces or people in the visual modality from face cues
Term
Amplitude of a Wave (perceptual dimension)
Definition
loudness
Term
Frequency of a wave (perceptual dimension)
Definition
pitch
Term
Complexity of a wave (perceptual dimension)
Definition
(timbre)
Term
Pathway of sound info
Definition
ear--> superior olivary nucleus--> lateral lemniscus--> inferior colliculus-->auditory cortex
Term
Phase Lock
Definition
below 200 hertz, cells code by using neurons that fire at certain points in a wave (apex)
Term
high frequency location of sensitivity in the basilar membrane
Definition
entry of cochlea
Term
low frequency response in the basilar membrane
Definition
end of basilar membrane end of cochlea
Term
Linking of hair cells
Definition
linked by actin that opens the gated channels by SHEARING FORCE
Term
Loudness at high frequencies
Definition
the loudness of high frequency sounds will be recored by neural firing rate. Cannot be used for low sounds
Term
Loudness at lower frequencies is believed to be coded by x amount of neurons firing at the same time
Definition
ok
Term
Perception of Location
Definition
@ low freq, time of arrival is used. There is a slight difference in time of arrival.
Term
Perception of location at high frequencies
Definition
sound location is coded using intensity. High freq will be dampened by head shadow
Term
Coincidence Detectors
Definition
a coincidence measures two things happening at once. Differences in arrival time does it come from left first? right first?
Term
Semicircular canals of the vestibular system
Definition
1. respond to angular acceleration and changes in head rotation
Term
Vestibular sacs
Definition
respons to gravity and tilting of head (orientation)
Term
Semicircular canals
Definition
filled w/ endolymph, respond to rotation on a single plane, rotation causes endolymph to flow and cupula to move.
Term
Uticle/Saccule/Otoliths
Definition
shift their weight when head is tilted, causes membrane to move cilia, K+ enters and action potentials are sent to vestibular sys
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