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Biopsychology
CHAPTER FOUR: Psychopharmacology
60
Psychology
Undergraduate 4
10/09/2013

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Term
Neurotransmitter
Definition
A chemical messenger that communicates across a synapse.
Term
Neuromodulator
Definition
A chemical messenger that communicates with target cells more distant than the synapse by diffusing away from the point of release.
Term
Neurohormone
Definition
A chemical messenger that communicates with target cells at great distance, often by traveling through the circulation.
Term
Small-molecule transmitter
Definition
One of a group of chemical messengers that includes amino acids and amines.
Term
Neuropeptide
Definition
A peptide that acts as a neurotransmitter, a neuromodulator, or a neurohormone.
Term
Amino Acid
Definition
An essential component of proteins.
Term
Acetylcholine (ACh)
Definition
A major small-molecule neurotransmitter used at the neurotransmitter used at the neuromuscular junction, in the autonomic nervous system, and in the central nervous system.
Term
Acetylcholinesterase (AChE)
Definition
An enzyme that breaks down the neurotransmitter acetylcholine.
Term
Nicotinic Receptor
Definition
A postsynaptic receptor that responds to nicotine and ACh.
Term
Muscarinic Receptor
Definition
A postsynaptic receptor that responds to both ACh and muscarine.
Term
Monomine
Definition
One of a major group of biogenic amine neurotransmitters, including dopamine, norepinephrine, epinephrine, and serotonin.
Term
Catecholamine
Definition
A member of a group of related biogenic amines that includes dopamine, epinephrine, and norepinephrine.
Term
Indoleamine
Definition
One of a subgroup of monoamines, including serotonin and melatonin.
Term
Monoamine Oxidase (MAO)
Definition
An enzyme that breaks down monoamines.
Term
L-Dopa
Definition
A substance produced during the synthesis of catecholamines that is also administered as a treatment for Parkinson's disease.
Term
Dopamine
Definition
A major monoamine and catecholamine neurotransmitter implicated in motor control, reward, and psychosis.
Term
Norepinephrine
Definition
A major monoamine and catecholamine neurotransmitter.
Term
Epinephrine
Definition
One of the monoamine/catecholamine neurotransmitters; also known as adrenaline.
Term
Serotonin
Definition
A major monoamine and indoleamine neurotransmitter believed to participate in the regulation of mood, sleep, and appetite.
Term
Glutamate
Definition
A major excitatory amino acid neurotransmitter.
Term
Gamma-aminobutyric acid
Definition
A major inhibitory amino acid neurotransmitter.
Term
Adenosine
Definition
A byproduct of adenosine triphosphate (ATP) that functions as a neurotransmitter.
Term
Nitric Oxide (NO)
Definition
A gas that performs a type of signaling between neurons.
Term
Agonist
Definition
Substance that promotes the activity of a neurotransmitter.
Term
Antagonist
Definition
Substance that reduces the action of a neurotransmitter.
Term
Reserpine
Definition
A substance derived from a plant that depletes supplies of monoamines by interfering with the uptake of monoamines into synaptic vesicles; used to treat high blood pressure but often produces depression.
Term
Botulism
Definition
A fatal condition produced by bacteria in spoiled food, in which a toxin produced by the bacteria prevents the release of ACh.
Term
Curare
Definition
A substance derived from Amazonian plants that causes paralysis by blocking the nicotinic ACh receptor.
Term
Benzodiazepine
Definition
A major tranquilizer that acts as a GABA agonist.
Term
Barbituate
Definition
A drug that produces strong sedation by acting as a GABA agonist.
Term
Reuptake Inhibitor
Definition
Substance that interferes with the transport of released neurotransmitter molecules back into the presynaptic terminal.
Term
Area Postrema
Definition
A brainstem area, in which the blood-brain barrier is more permeable, that triggers vomitting in response to the detection of circulating toxins.
Term
Placebo effect
Definition
Perceived benefit from inactive substances or procedures.
Term
Double-blind experiment
Definition
A research design in which neither the participant nor the experimenter knows whether the participant is receiving a drug or a placebo until after the research is concluded.
Term
Tolerance
Definition
The process in which more of a drug is needed to produce the same effect.
Term
Withdrawal
Definition
The symptoms that occur when certain addictive drugs are no longer administered or are administered in smaller quantities.
Term
Addiction
Definition
A compulsive craving for drug effects or other experience.
Term
Nucleus accumbens
Definition
A dopaminergic structure believed to participate in reward and addiction.
Term
Psychoactive drug
Definition
A drug that produces changes in mental processes.
Term
Caffeine
Definition
A stimulant drug found in coffee, tea, cola, and chocolate that acts as an antagonist to adenosine.
Term
Nicotine
Definition
A stimulant drug that is the major active component found in tobacco.
Term
Cocaine
Definition
A powerful, addictive dopamine agonist derived from the leaves of coca plant of South America.
Term
Amphetamine
Definition
A highly addictive drug that acts as a potent dopamine agonist.
Term
Methamphetamine
Definition
A variation of amphetamine that is cheaply produced and widely abused in the United States.
Term
Ectasy (MDMA)
Definition
A close relative of amphetamine that produces its behavioral effects by stimulating the release of serotonin.
Term
Gamma-Hydroxybutyrate
Definition
An illegal liquid sedative that appears to affect the threshold of response for a number of neurotransmitters.
Term
Morphine
Definition
A compound extracted from opium, used to treat pain.
Term
Codeine
Definition
An opium derivative used medicinally for cough suppression and pain relief.
Term
Opiate
Definition
An active substance derived from the opium poppy.
Term
Endorphin
Definition
A naturally occurring neuropeptide that is very closely related to opioids.
Term
Codeine
Definition
An opium derivative used medicinally for cough suppression and pain relief.
Term
Opiate
Definition
An active substance derived from the opium poppy.
Term
Endorphin
Definition
A naturally occurring neuropeptide that is very closely related to opioids.
Term
Tetrahydrocannabinol (THC)
Definition
The major ingredient of cannabis.
Term
Anandamide
Definition
A naturally occurring brain chemical that interacts with cannabinoid receptors.
Term
sn-2 arachidonylglycerol (2-AG)
Definition
A possible candidate for a naturally occurring cannabinoid in the nervous system.
Term
Mescaline
Definition
The active hallucinogenic ingredient found in the peyote cactus.
Term
Phencyclidine (PCP)
Definition
A hallucinogen that acts as an antagonist at the NMDA glutamate receptor.
Term
Lysergic Acid Diethylamide (LSD)
Definition
A hallucinogenic drug that resembles serotonin.
Term
St. John's Wort
Definition
An herb that is frequently used to self-treat mild depression.
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