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BioPsych15
Striatal Structures
7
Psychology
Undergraduate 1
06/11/2010

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Term
striatum
Definition
connects many non-motor structures with the primary motor cortex via the basal ganglia
Term
nucleus accumbens
Definition
ventral striatum
-highly involved in turning motivation into ACTION
-start of motor output of limbic system
-approach or avoid
NAC ACTIVATED!
-rich in dopamine receptors (receives signals from VTA)
Term
reward center
Definition
all things good increase activity in nucleus accumbens
-food, water, sex, drugs
damage=reduction in eating, drinking, sex, drug-taking (depression=low activity here)
Term
dopamine hypothesis of addiction
Definition
ability of drugs of abuse to elevate and to sensitize elevation in nucleus accumbens levels of dopamine is responsible for motivation for the effects of the drug!
Term
basal ganglia
Definition
circuit of inter-connected brain regions
-initiation, coordination, and control of motor movements
-procedural memory
Term
huntington's
Definition
loss of striatal inhibitory GABA interneurons
-hyperactivity of NSDS
Term
parkinson's
Definition
loss of SN dopamine neurons
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